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Delays in protein synthesis cause a confounding effect when constructing Gene Regulatory Networks (GRNs) from RNA-sequencing time-series data. Accurate GRNs can be very insightful when modelling development, disease pathways, and drug…

Molecular Networks · Quantitative Biology 2020-10-07 Jacob Moss , Pietro Lió

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

Neural and Evolutionary Computing · Computer Science 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

The relations, rather than the elements, constitute the structure of networks. We therefore develop a systematic approach to the analysis of networks, modelled as graphs or hypergraphs, that is based on structural properties of…

Discrete Mathematics · Computer Science 2020-12-08 Marzieh Eidi , Amirhossein Farzam , Wilmer Leal , Areejit Samal , Jürgen Jost

While previous works have shown that an overwhelming number of scale-free networks are sparse, there still exist some real-world networks including social networks, urban networks, information networks, which are by observation dense. In…

Social and Information Networks · Computer Science 2020-10-29 Fei Ma , Xiaomin Wang , Ping Wang , Xudong Luo

Structural changes in a network representation of a system (e.g.,different experimental conditions, time evolution), can provide insight on its organization, function and on how it responds to external perturbations. The deeper…

Data Analysis, Statistics and Probability · Physics 2021-01-04 Leonardo L. Portes , Michael Small

Hierarchical tree structures are common in many real-world systems, from tree roots and branches to neuronal dendrites and biologically inspired artificial neural networks, as well as in technological networks for organizing and searching…

Statistical Mechanics · Physics 2025-02-04 Davide Cipollini , Lambert Schomaker

The availability of large scale streaming network data has reinforced the ubiquity of power-law distributions in observations and enabled precision measurements of the distribution parameters. The increased accuracy of these measurements…

Physics and Society · Physics 2021-08-23 Pat Devlin , Jeremy Kepner , Ashley Luo , Erin Meger

In this paper, we develop a dynamic framework for the modeling and analysis of social networks to work with web documents. We illustrate the model with features of web, design a form to analyze relationships of attributes as a modality of…

Probability · Mathematics 2012-07-18 Mahyuddin K. M. Nasution , Shahrul Azman Noah

Seeking effective neural networks is a critical and practical field in deep learning. Besides designing the depth, type of convolution, normalization, and nonlinearities, the topological connectivity of neural networks is also important.…

Computer Vision and Pattern Recognition · Computer Science 2020-08-20 Kun Yuan , Quanquan Li , Jing Shao , Junjie Yan

Networks have in recent years emerged as an invaluable tool for describing and quantifying complex systems in many branches of science. Recent studies suggest that networks often exhibit hierarchical organization, where vertices divide into…

Machine Learning · Statistics 2008-11-05 Aaron Clauset , Cristopher Moore , M. E. J. Newman

Genetic regulatory networks enable cells to respond to the changes in internal and external conditions by dynamically coordinating their gene expression profiles. Our ability to make quantitative measurements in these biochemical circuits…

Biological Physics · Physics 2015-03-17 Aleksandra M Walczak , Gašper Tkačik

A key ingredient of current models proposed to capture the topological evolution of complex networks is the hypothesis that highly connected nodes increase their connectivity faster than their less connected peers, a phenomenon called…

Statistical Mechanics · Physics 2009-11-07 H. Jeong , Z. Neda , A. -L. Barabasi

Many real networks such as the World Wide Web, financial, biological, citation and social networks have a power-law degree distribution. Networks with this feature are also called scale-free. Several models for producing scale-free networks…

Social and Information Networks · Computer Science 2016-12-23 Akmal Artikov , Aleksandr Dorodnykh , Yana Kashinskaya , Egor Samosvat

Gene regulatory networks play a crucial role in controlling an organism's biological processes, which is why there is significant interest in developing computational methods that are able to extract their structure from high-throughput…

Machine Learning · Statistics 2019-09-11 Ioan Gabriel Bucur , Tom Claassen , Tom Heskes

Molecular networks guide the biochemistry of a living cell on multiple levels: its metabolic and signalling pathways are shaped by the network of interacting proteins, whose production, in turn, is controlled by the genetic regulatory…

Soft Condensed Matter · Physics 2009-11-07 Sergei Maslov , Kim Sneppen

We use a generalised version of the individual-based Tangled Nature model of evolutionary ecology to study the relationship between ecosystem structure and evolutionary history. Our evolved model ecosystems typically exhibit interaction…

Populations and Evolution · Quantitative Biology 2007-05-23 Simon Laird , Henrik Jeldtoft Jensen

We provide a framework for modeling social network formation through conditional multinomial logit models from discrete choice and random utility theory, in which each new edge is viewed as a "choice" made by a node to connect to another…

Social and Information Networks · Computer Science 2020-05-22 Jan Overgoor , Austin R. Benson , Johan Ugander

Social network structures play an important role in the lives of animals by affecting individual fitness and the spread of disease and information. Nevertheless, we still lack a good understanding of how these structures emerge from the…

Physics and Society · Physics 2026-02-16 Josefine Bohr Brask , Andreas Koher , Darren P. Croft , Sune Lehmann

Latent variable models for network data extract a summary of the relational structure underlying an observed network. The simplest possible models subdivide nodes of the network into clusters; the probability of a link between any two nodes…

Machine Learning · Computer Science 2012-07-03 Konstantina Palla , David Knowles , Zoubin Ghahramani

Mechanistic models can provide an intuitive and interpretable explanation of network growth by specifying a set of generative rules. These rules can be defined by domain knowledge about real-world mechanisms governing network growth or may…

Social and Information Networks · Computer Science 2025-12-04 Maxwell H Wang , Till Hoffmann , Jukka-Pekka Onnela