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Static light scattering is a popular physical chemistry technique that enables calculation of physical attributes such as the radius of gyration and the second virial coefficient for a macromolecule (e.g., a polymer or a protein) in…

Applications · Statistics 2021-11-17 Fan Yin , Domarin Khago , Rachel W. Martin , Carter T. Butts

A fast and accurate grid-based method with low memory requirement is presented to calculate volume characteristics in molecular systems. The distribution of volume and packing density is characterized in globular proteins, where void space…

Biological Physics · Physics 2018-10-23 Jenny Farmer , Sheridan B. Green , Donald J. Jacobs

The envelope of an elliptical Gaussian complex vector, or equivalently, the amplitude or norm of a bivariate normal random vector has application in many weather and signal processing contexts. We explicitly characterize its distribution in…

Statistics Theory · Mathematics 2026-02-03 Sattwik Ghosal , Ranjan Maitra

We study distributions of random vectors whose components are second order polynomials in Gaussian random variables. Assuming that the law of such a vector is not absolutely continuous with respect to Lebesgue measure, we derive some…

Probability · Mathematics 2013-05-28 Vladimir I. Bogachev , Egor D. Kosov , Ivan Nourdin , Guillaume Poly

Theories of protein crystallization based on spheres that form close-packed crystals predict optimal assembly within a `slot' of second virial coefficients and enhanced assembly near the metastable liquid-vapor critical point. However, most…

Soft Condensed Matter · Physics 2014-04-04 Thomas K. Haxton , Stephen Whitelam

The projected normal distribution, also known as the angular Gaussian distribution, is obtained by dividing a multivariate normal random variable $\mathbf{x}$ by its norm $\sqrt{\mathbf{x}^T \mathbf{x}}$. The resulting random variable…

Methodology · Statistics 2025-06-24 Daniel Herrera-Esposito , Johannes Burge

Localization properties of residue fluctuations in globular proteins are studied theoretically by using the Gaussian network model. Participation ratio for each residue fluctuation mode is calculated. It is found that the relationship…

Biological Physics · Physics 2009-11-10 Yinhao Wu , Xianzhang Yuan , Xia Gao , Haiping Fang , Jian Zi

An expression for the joint probability distribution of the principal curvatures at an arbitrary point in the ensemble of isosurfaces defined on isotropic Gaussian random fields on Rn is derived. The result is obtained by deriving symmetry…

Mathematical Physics · Physics 2007-05-23 Paulo R. S. Mendonca , Rahul Bhotika , James V. Miller

We show that by using intuitive and accessible molecular features it is possible to predict the temperature-dependent second virial coefficient of organic and inorganic compounds using Gaussian process regression. In particular, we built a…

Chemical Physics · Physics 2021-02-24 Miruna T. Cretu , Jesús Pérez-Ríos

We study the regularity of densities of distributions that are polynomial images of the standard Gaussian measure on $\mathbb{R}^n$. We assume that the degree of a polynomial is fixed and that each variable enters to a power bounded by…

Probability · Mathematics 2020-07-28 Egor Kosov

Recently, we presented a framework for understanding protein structure based on the idea that simple constructs of holding hands or touching of objects can be used to rationalize the common characteristics of globular proteins. We developed…

Soft Condensed Matter · Physics 2023-06-21 Tatjana Škrbić , Achille Giacometti , Trinh X. Hoang , Amos Maritan , Jayanth R. Banavar

Bacteria typically have a few thousand different proteins. The number of proteins with a given charge is a roughly Gaussian function of charge - centred near zero, and with a width around ten (in units of the charge on the proton). We have…

Soft Condensed Matter · Physics 2009-11-07 Richard P. Sear

In this note, we define a Gaussian probability distribution over matrices. We prove some useful properties of this distribution, namely, the fact that marginalization, conditioning, and affine transformations preserve the matrix Gaussian…

Probability · Mathematics 2018-06-22 Shane Barratt

It is shown that the density of modes of the vibrational spectrum of globular proteins is universal, i.e., regardless of the protein in question it closely follows one universal curve. The present study, including 135 proteins analyzed with…

Biological Physics · Physics 2018-06-29 Hyuntae Na , Guang Song , Daniel ben-Avraham

The spectrum profile that emerges in molecular spectroscopy and atmospheric radiative transfer as the combined effect of Doppler and pressure broadenings is known as the Voigt profile function. Because of its convolution integral…

Mathematical Physics · Physics 2008-06-12 Gianni Pagnini , Francesco Mainardi

The copy number of any protein fluctuates among cells in a population; characterizing and understanding these fluctuations is a fundamental problem in biophysics. We show here that protein distributions measured under a broad range of…

This survey for mathematicians summarizes several works by the author on protein geometry and protein function with applications to viral glycoproteins in general and the spike glycoprotein of the SARS-CoV-2 virus in particular. Background…

Biomolecules · Quantitative Biology 2022-08-19 Robert Penner

Except for certain parameter values, a closed form formula for the mode of the generalized hyperbolic (GH) distribution is not available. In this paper, we exploit results from the literature on modified Bessel functions and their ratios to…

Statistics Theory · Mathematics 2020-09-03 Robert E. Gaunt , Milan Merkle

The Fourier-discrete-peridogram are used to identify pulsation modes in variables. We have found two pulsation modes in V1 and V2 among 13 new variables as described by Abbas et al.. The five variables V9 to V13 are not shown close to…

Solar and Stellar Astrophysics · Physics 2016-06-30 Gireesh C. Joshi , R. K. Tyagi

The classical approach to diffusion processes is based on Fick's law that the flux is proportional to the concentration gradient. Various phenomena occurring during propagation of penetrating liquids in polymers show that this type of…

Analysis of PDEs · Mathematics 2010-12-10 Dmitry A. Vorotnikov
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