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This paper presents a theoretical analysis of the closure kinetics of a polymer with hydrodynamic interactions. This analysis, which takes into account the non-Markovian dynamics of the end-to-end vector and relies on the preaveraging of…

We investigate theoretically the physics of diffusion-limited intramolecular polymer reactions. The present work completes and goes beyond a previous study [Nat. Chem. 4, 268 (2012)] that showed that the distribution of the polymer…

Statistical Mechanics · Physics 2015-06-12 T. Guérin , O. Bénichou , R. Voituriez

The computation of the probability of the first-passage time through a given threshold of a stochastic process is a classic problem that appears in many branches of physics. When the stochastic dynamics is markovian, the probability admits…

Statistical Mechanics · Physics 2009-05-05 Michele Maggiore , Antonio Riotto

Dimerization and subsequent aggregation of polymers and biopolymers often occur under nonequilibrium conditions. When the initial state of the polymer is not collapsed or the final folded native state, the dynamics of dimerization can…

Soft Condensed Matter · Physics 2024-11-19 Sangita Mondal , Ved Mahajan , Biman Bagchi

How much time does it take for a fluctuating system, such as a polymer chain, to reach a target configuration that is rarely visited -- typically because of a high energy cost ? This question generally amounts to the determination of the…

Statistical Mechanics · Physics 2020-03-18 Nicolas Levernier , Olivier Bénichou , Raphaël Voituriez , Thomas Guérin

Splitting probabilities quantify the likelihood of a given outcome out of competitive events. This key observable of random walk theory, historically introduced as the gambler's ruin problem, is well understood for memoryless (Markovian)…

Statistical Mechanics · Physics 2025-04-01 M. Dolgushev , T. V. Mendes , B. Gorin , K. Xie , N. Levernier , O. Bénichou , H. Kellay , R. Voituriez , T. Guérin

Describing the kinetics of polymer reactions, such as the formation of loops and hairpins in nucleic acids or polypeptides, is complicated by the structural dynamics of their chains. Although both intramolecular reactions, such as…

Chemical Physics · Physics 2012-09-10 Thomas Guérin , Olivier Bénichou , Raphaël Voituriez

We develop a simple recursive approach to treat reversible condensation polymerization with cyclization. Based upon a minimum set of balance equations, the law of mass action, Gaussian chain statistics, and the assumption of independent…

Soft Condensed Matter · Physics 2023-02-10 Michael Lang , Kiran Suresh Kumar

The process of polymer condensation, i.e. the formation of bonds between reactive end-groups, is ubiquitous in both industry and biology. Here we study generic systems undergoing polymer condensation in competition with cyclisation. Using a…

This study deals with polymer looping, an important process in many chemical and biological systems. We investigate basic questions on the looping dynamics of a polymer under tension using the freely-jointed chain (FJC) model. Previous…

Statistical Mechanics · Physics 2024-10-03 Wout Laeremans , Anne Floor den Ouden , Jef Hooyberghs , Wouter G. Ellenbroek

The non-Markovian nature of polymer motions is accounted for in folding kinetics, using frequency-dependent friction. Folding, like many other problems in the physics of disordered systems, involves barrier crossing on a correlated energy…

Statistical Mechanics · Physics 2009-10-30 Steven S. Plotkin , Peter G. Wolynes

In this paper, we investigate a stochastic model describing the time evolution of a polymerization process. A polymer is a macro-molecule resulting from the aggregation of several elementary sub-units called monomers. Polymers can grow by…

Probability · Mathematics 2018-08-24 Philippe Robert , Wen Sun

We study the dynamics of a polymer when it is quenched from a $\theta$ solvent into a good or bad solvent by means of a Langevin equation. The variation of the radius of gyration is studied as a function of time. For the first stage of…

Soft Condensed Matter · Physics 2008-02-03 E. Pitard , H. Orland

By simulating the first order globule-crystal transition of a flexible homopolymer chain, both by collision dynamics and Monte Carlo with non-kinetic moves, we show that the effective and the thermodynamic transition temperatures are…

Soft Condensed Matter · Physics 2017-08-23 S. Ruzicka , D. Quigley , M. P. Allen

Abstract polymer models are systems of weighted objects, called polymers, equipped with an incompatibility relation. An important quantity associated with such models is the partition function, which is the weighted sum over all sets of…

Probability · Mathematics 2025-12-12 Tobias Friedrich , Andreas Göbel , Martin S. Krejca , Marcus Pappik

Polymer models are a widely used tool to study the prebiotic formation of metabolism at the origins of life. Counts of the number of reactions in these models are often crucial in probabilistic arguments concerning the emergence of…

Molecular Networks · Quantitative Biology 2021-04-14 Oliver Weller-Davies , Mike Steel , Jotun Hein

We study a stochastic model of a copolymerization process that has been extensively investigated in the physics literature. The main questions of interest include: (i) what are the criteria for transience, null recurrence, and positive…

Probability · Mathematics 2025-12-12 David F. Anderson , Jingyi Ma , Praful Gagrani

Hybrid molecular dynamics/Monte Carlo simulations used to study melts of unentangled, thermoreversibly associating supramolecular polymers. In this first of a series of papers, we describe and validate a model that is effective in…

Soft Condensed Matter · Physics 2015-05-13 Robert S. Hoy , Glenn H. Fredrickson

In a number of experimental situations, single polymer molecules can be suspended in a vacuum. Here collisions between such molecules are considered. The limit of high collision velocity is investigated numerically for a variety of…

Soft Condensed Matter · Physics 2015-05-19 J. M. Deutsch

While the dynamics of polymer chains in equilibrium media is well understood by now, the polymer dynamics in active non-equilibrium environments can be very different. Here we study the dynamics of polymers in a viscous medium containing…

Soft Condensed Matter · Physics 2017-06-23 Jaeoh Shin , Andrey G. Cherstvy , Won Kyu Kim , Vasily Zaburdaev
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