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This paper is devoted to pulse solutions in FitzHugh--Nagumo systems that are coupled parabolic equations with rapidly periodically oscillating coefficients. In the limit of vanishing periods, there arises a two-scale FitzHugh--Nagumo…

Dynamical Systems · Mathematics 2017-07-27 Pavel Gurevich , Sina Reichelt

We study the dynamics of a reaction-diffusion system composed of two mutually coupled excitable fibers. We focus on the situation in which dynamical properties of the two fibers are not identical because of the parameter difference between…

Pattern Formation and Solitons · Physics 2021-01-29 Hiromichi Suetani , Tatsuo Yanagita , Kazuyuki Aihara

We establish the existence and nonlinear stability of travelling pulse solutions for the discrete FitzHugh-Nagumo equation with infinite-range interactions close to the continuum limit. For the verification of the spectral properties, we…

Dynamical Systems · Mathematics 2019-06-07 W. M. Schouten , H. J. Hupkes

We study the effects of nonlocal control of pulse propagation in excitable media. As a generic example for an excitable medium the FitzHugh-Nagumo model with diffusion in the activator variable is considered. Nonlocal coupling in form of an…

Pattern Formation and Solitons · Physics 2015-06-19 Clemens A. Bachmair , Eckehard Schöll

The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture,…

Neurons and Cognition · Quantitative Biology 2007-05-23 F. Berezovskaya , E. Camacho , S. Wirkus , G. Karev

We introduce a geometrical extension of the FitzHugh-Nagumo equations describing propagation of electrical impulses in nerve axons. In this extension, the axon is modeled as a warped cylinder, rather than a straight line, as is usually…

Analysis of PDEs · Mathematics 2021-05-12 Afroditi Talidou , Almut Burchard , Israel Michael Sigal

We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

Pattern Formation and Solitons · Physics 2019-05-07 Aleksandra Gawlik , Vsevolod Vladimirov , Sergii Skurativskyi

Many multicellular communities propagate signals in a directed manner via excitable waves. Cell-to-cell heterogeneity is a ubiquitous feature of multicellular communities, but the effects of heterogeneity on wave propagation are still…

Biological Physics · Physics 2020-04-22 Xiaoling Zhai , Joseph W. Larkin , Gürol M. Süel , Andrew Mugler

The FitzHugh-Nagumo equation, which was derived as a simplification of the Hodgkin-Huxley model for nerve impulse propagation, has been extensively studied as a paradigmatic activator-inhibitor system. We consider the version of this system…

Dynamical Systems · Mathematics 2018-03-15 Paul Cornwell , Christopher K. R. T. Jones

In this paper, we report on the generation and propagation of traveling pulses in a homogeneous network of diffusively coupled, excitable, slow-fast dynamical neurons. The spatially extended system is modelled using the nearest neighbor…

Pattern Formation and Solitons · Physics 2024-06-19 Arnab Mondal , Argha Mondal , M. A. Aziz-Alaoui , Ranjit Kumar Upadhyay , Sanjeev Kumar Sharma , Chris G. Antonopoulos

We design and study splitting integrators for the temporal discretization of the stochastic FitzHugh--Nagumo system. This system is a model for signal propagation in nerve cells where the voltage variable is solution of a one-dimensional…

Numerical Analysis · Mathematics 2022-07-22 Charles-Edouard Bréhier , David Cohen , Giuseppe Giordano

A quantitative description of pulses and wave trains in the spatially discrete Hodgkin-Huxley model for myelinated nerves is given. Predictions of the shape and speed of the waves and the thresholds for propagation failure are obtained. Our…

Neurons and Cognition · Quantitative Biology 2009-11-11 A. Carpio

For a coupled slow--fast FitzHugh--Nagumo(FHN) equation derived from a reaction-diffusion-mechanics (RDM) model, Holzer, Doelman and Kaper in 2013 studied existence and stability of the travelling pulse, which consists of two fast orbit…

Dynamical Systems · Mathematics 2023-02-14 Qi Qiao , Xiang Zhang

We consider the problem of initiation of propagating wave in a one-dimensional excitable fiber. In the FitzHugh-Nagumo theory, the key role is played by ``critical nucleus'' and ``critical pulse'' solutions whose (center-)stable manifold is…

Pattern Formation and Solitons · Physics 2009-11-13 I. Idris , V. N. Biktashev

Motivated by pulse-replication phenomena observed in the FitzHugh--Nagumo equation, we investigate traveling pulses whose slow-fast profiles exhibit canard-like transitions. We show that the spectra of the PDE linearization about such…

Pattern Formation and Solitons · Physics 2021-02-15 Paul Carter , Jens D. M. Rademacher , Björn Sandstede

Understanding how external stimuli propagate in neural systems is an important challenge in the fields of neuroscience and nonlinear dynamics. Despite extensive studies over several decades, this problem remains poorly understood. In this…

Neurons and Cognition · Quantitative Biology 2025-03-13 L. Messee Goulefack , C. Masoller , R. Yamapi , C. Anteneodo

The FitzHugh-Nagumo equation, originally conceived in neuroscience during the 1960s, became a key model providing a simplified view of excitable neuron cell behavior. Its applicability, however, extends beyond neuroscience into fields like…

Pattern Formation and Solitons · Physics 2025-01-08 Daniel Cebrián-Lacasa , Pedro Parra-Rivas , Daniel Ruiz-Reynés , Lendert Gelens

Pulse propagation in nonlinear arrays continues to be of interest because it provides a possible mechanism for energy transfer with little dispersion. Here we show that common measures of pulse dispersion might be misleading; in strongly…

Soft Condensed Matter · Physics 2009-11-10 Alexandre Rosas , Katja Lindenberg

We introduce discrete and p-adic continuous versions of the FitzHugh-Nagumo system on the one-dimensional p-adic unit ball. We provide criteria for the existence of Turing patterns. We present extensive simulations of some of these systems.…

Pattern Formation and Solitons · Physics 2023-11-23 L. F. Chacón-Cortés , C. A. Garcia-Bibiano , W. A. Zúñiga-Galindo

A commonly accepted feature of an excitable medium is that a local excitation leads to a propagation of circular or spiral excitation wave-fronts. This is indeed the case in fully excitable medium. However, with a decrease of an…

Emerging Technologies · Computer Science 2019-04-16 Andrew Adamatzky
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