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Biological membranes are host to proteins and molecules which may form domain-like structures resulting in spatially-varying material properties. Vesicles with such heterogeneous membranes can exhibit intricate shapes at equilibrium and…

Soft Condensed Matter · Physics 2023-06-22 Prerna Gera , David Salac , Saverio E. Spagnolie

We examine the shape of droplets atop deformable thin elastomeric films prepared with an anisotropic tension. As the droplets generate a deformation in the taut film through capillary forces, they assume a shape that is elongated along the…

Soft Condensed Matter · Physics 2017-05-17 Rafael D. Schulman , René Ledesma-Alonso , Thomas Salez , Elie Raphaël , Kari Dalnoki-Veress

We consider the role of nonlamellar-forming lipids in biological membranes by examining fluctuations, within the random phase approximation, of a model mixture of two lipids, one of which forms lamellar phases while the other forms inverted…

Soft Condensed Matter · Physics 2009-10-31 Xiao-jun Li , M. Schick

Nature uses elongated shapes and filaments to build stable structures, generate motion, and allow complex geometric interactions. In this Review, we examine the role of biological filaments across different length scales. From the molecular…

Soft Condensed Matter · Physics 2025-07-25 Jan Cammann , Hannah Laeverenz-Schlogelhofer , Kirsty Y. Wan , Marco G. Mazza

Recent progress in the fusion of biological membranes is reviewed to highlight the central role played by the line tension, which permits exquisite control of the process.

Soft Condensed Matter · Physics 2009-11-11 M. Schick , K. Katsov , M. Mueller

Diffusion in cell biology is important and complicated. Diffusing particles must contend with a complex environment as they make their way through the cell. We analyze a particular type of complexity that arises when diffusing particles…

Subcellular Processes · Quantitative Biology 2018-09-06 Ben Fogelson , James P. Keener

In the framework of a phase field model of a single cell crawling on a substrate, we investigate how the properties of the cell membrane affect the shape and motility of the cell. Since the membrane influences the cell dynamics on multiple…

Soft Condensed Matter · Physics 2016-03-23 Benjamin Winkler , Igor S. Aranson , Falko Ziebert

A coarse-grained computational model is used to investigate the effect of a fluid membrane on patchy-particle assembly into biologically-relevant structures motivated by viral cores and clathrin. For cores, we demonstrate a non-monotonic…

Soft Condensed Matter · Physics 2012-11-09 Richard Matthews , Christos N. Likos

Formation and rupture of vesicles is a fundamental process underlying diverse phenomena in biology, materials science, and biomedical applications. Vesicles form when the area of a growing disk-like membrane exceeds a critical value at…

Soft Condensed Matter · Physics 2025-11-11 Seungwoo Shin , Federico Cao , Robert A. Pelcovits , Thomas R. Powers , Zvonimir Dogic

A feature of current membrane systems is the fact that objects and membranes are persistent. However, this is not true in the real world. In fact, cells and intracellular proteins have a well-defined lifetime. Inspired from these biological…

Formal Languages and Automata Theory · Computer Science 2009-10-08 Bogdan Aman , Gabriel Ciobanu

Biological and biomimetic membranes often contain aggregates of embedded or adsorbed macromolecules. In this article, the indirect interactions of cylindrical objects adhering to a planar membrane are considered theoretically. The adhesion…

Soft Condensed Matter · Physics 2009-11-10 Thomas R. Weikl

Tuning cell rearrangements is essential in collective cell movement that underlies cancer progression, wound repair, and embryonic development. A key question is how tissue material properties and morphology emerge from cellular factors…

Biological Physics · Physics 2025-07-15 Soumyadipta Ray , Santidan Biswas , Dipjyoti Das

We set up the statistical mechanics for a nearly flat, thermally equilibrated fluid membrane, attached to an elastic network through one of its sides. We predict that the resulting structural (inversion) asymmetry of the membrane, notably…

Soft Condensed Matter · Physics 2016-10-07 Tirthankar Banerjee , Niladri Sarkar , Abhik Basu

We carry out Monte Carlo simulations of a colloidal fluid membrane composed of chiral rod-like viruses. The membrane is modeled by a triangular mesh of beads connected by bonds in which the bonds and beads are free to move at each Monte…

Soft Condensed Matter · Physics 2020-09-23 Lijie Ding , Robert A. Pelcovits , Thomas R. Powers

We study the morphology of a fluid membrane in spherical confinement. When the area of the membrane is slightly larger than the area of the outer container, a single axisymmetric invagination is observed. For higher area, self-contact…

Biological Physics · Physics 2012-03-26 Osman Kahraman , Norbert Stoop , Martin Michael Mueller

Biological cells can actively tune their intracellular architecture according to their overall shape. Here we explore the rheological implication of such coupling in a minimal model of a dense cellular material where each cell exerts an…

Soft Condensed Matter · Physics 2022-04-13 Shao-Zhen Lin , Matthias Merkel , Jean-François Rupprecht

When a ribbon or tube is twisted far enough it forms buckles and wrinkles. Its new geometry can be strikingly ordered, or hopelessly disordered. Here we study this process in a tube with hybrid boundary conditions: one end a cylinder, and…

Soft Condensed Matter · Physics 2025-11-27 Pan Dong , Nathan C. Keim , Joseph D. Paulsen

Lipid membranes, the barrier defining living cells and many of their sub-compartments, bind to a wide variety of nano- and micro-meter sized objects. In the presence of strong adhesive forces, membranes can strongly deform and wrap the…

We carry out Monte Carlo simulations on fluid membranes with orientational order and multiple edges in the presence and absence of external forces. The membrane resists bending and has an edge tension, the orientational order couples with…

Soft Condensed Matter · Physics 2023-11-01 Lijie Ding , Robert A. Pelcovits , Thomas R. Powers

We construct a micromechanical version of an early model for topologically constrained polymers -- a 2D chain amongst point-like uncrossable obstacles -- which allows us to explicitly elucidate the role of topological forces beyond…

Soft Condensed Matter · Physics 2022-07-13 Ahmad K. Omar , Yuyuan Lu , Lijia An , Zhen-Gang Wang