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In this paper, a new method to efficiently simulate diffusion controlled second order chemical reactions is derived and applied to site-specific DNA-binding proteins. The protein enters a spherical cell and propagates via two competing…

Biological Physics · Physics 2009-11-11 Holger Merlitz , Konstantin V. Klenin , Chen-Xu Wu , Jörg Langowski

Intransitivity is supposed to be a main reason for deficits in coevolutionary progress and inheritable superiority. Besides, coevolutionary dynamics is characterized by interactions yielding subjective fitness, but aiming at solutions that…

Neural and Evolutionary Computing · Computer Science 2016-11-30 Hendrik Richter

Binding interactions between proteins and other molecules mediate numerous cellular processes, including metabolism, signaling, and regulation of gene expression. These interactions evolve in response to changes in the protein's chemical or…

Populations and Evolution · Quantitative Biology 2015-02-19 Michael Manhart , Alexandre V. Morozov

Protein evolution underpins life, and understanding its behavior as a system is of great importance. However, our current models of protein evolution are arguably too simplistic to allow quantitative interpretation and prediction of…

The evolution of economic and innovation systems at the national scale is shaped by a complex dynamics, the footprint of which is the nested structure of the activities in which different countries are competitive. Nestedness is a…

General Economics · Economics 2023-08-15 Aurelio Patelli , Lorenzo Napolitano , Giulio Cimini , Emanuele Pugliese , Andrea Gabrielli

Prion and prion-like molecules are a type of self replicating aggregate protein that have been implicated in a variety of neurodegenerative diseases. Over recent decades the molecular dynamics of prions have been characterized both…

Populations and Evolution · Quantitative Biology 2022-07-06 Saul Acevedo , Alexander J. Stewart

Plasticity-led evolution is a form of evolution where a change in the environment induces novel traits via phenotypic plasticity, after which the novel traits are genetically accommodated over generations under the novel environment. This…

Populations and Evolution · Quantitative Biology 2023-01-18 Eden Tian Hwa Ng , Akira R. Kinjo

To our knowledge, the populations are generally assumed to be homogeneous in the traditional approach to evolutionary game dynamics. Here, we focus on the inhomogeneous populations. A simple model which can describe the inhomogeneity of the…

Physics and Society · Physics 2007-05-23 Xiaojie Chen , Feng Fu , Long Wang , Tianguang Chu

A simple cellular automata model for a two-group war over the same territory is presented. It is shown that a qualitative advantage is not enough for a minority to win. A spatial organization as well a definite degree of aggressiveness are…

Disordered Systems and Neural Networks · Physics 2016-08-31 Serge Galam , Bastien Chopard , Alexander Masselot , Michel Droz

The influence of an external random field on the competition process in a nonlinear open spatially extended system is analyzed numerically. A three-component model is chosen as the competition model in which a "weak" species can move in…

Pattern Formation and Solitons · Physics 2015-12-02 S. E. Kurushina , V. V. Maximov , E. A. Shapovalova , Yu. M. Romanovskii , I. P. Zavershinskii , D. S. Garipov

Population dynamics in systems composed of cyclically competing species has been of increasing interest recently. Here, we investigate a system with four or more species. Using mean field theory, we study in detail the trajectories in…

Populations and Evolution · Quantitative Biology 2015-05-27 C. H. Durney , S. O. Case , M. Pleimling , R. K. P. Zia

Evolutionary algorithms have been widely applied for solving dynamic constrained optimization problems (DCOPs) as a common area of research in evolutionary optimization. Current benchmarks proposed for testing these problems in the…

Neural and Evolutionary Computing · Computer Science 2019-07-10 Maryam Hasani-Shoreh , María-Yaneli Ameca-Alducin , Wilson Blaikie , Frank Neumann , Marc Schoenauer

One strategy for winning a coevolutionary struggle is to evolve rapidly. Most of the literature on host-pathogen coevolution focuses on this phenomenon, and looks for consequent evidence of coevolutionary arms races. An alternative…

Populations and Evolution · Quantitative Biology 2014-12-17 Erick Chastain , Rustom Antia , Carl T. Bergstrom

Non-uniform rates of morphological evolution and evolutionary increases in organismal complexity, captured in metaphors like "adaptive zones", "punctuated equilibrium" and "blunderbuss patterns", require more elaborate explanations than a…

Populations and Evolution · Quantitative Biology 2020-07-01 Iaroslav Ispolatov , Evgeniia Alekseeva , Michael Doebeli

Rich out of equilibrium collective dynamics of strongly interacting large assemblies emerge in many areas of science. Some intriguing and not fully understood examples are the glassy arrest in atomic, molecular or colloidal systems,…

Statistical Mechanics · Physics 2023-05-03 Leticia F. Cugliandolo

In this paper we study collective decision making on a multi-population, represented by a regular network of groups of individuals. Each group consists of a collection of players and every player can choose between two options. A group is…

Optimization and Control · Mathematics 2020-11-18 Wouter Baar , Dario Bauso

We study the evolution of asexual microorganisms with small mutation rate in fluctuating environments, and develop techniques that allow us to expand the formal solution of the evolution equations to first order in the mutation rate. Our…

Biological Physics · Physics 2009-11-06 Claus Wilke , Christopher Ronnewinkel

We analyze an interacting particle system with a Markov evolution of birth-and-death type. We have shown that a local competition mechanism (realized via a density dependent mortality) leads to a globally regular behavior of the population…

Mathematical Physics · Physics 2015-01-27 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy

In living cells, proteins combine 3D bulk diffusion and 1D sliding along the DNA to reach a target faster. This process is known as facilitated diffusion, and we investigate its dynamics in the physiologically relevant case of confined DNA.…

Soft Condensed Matter · Physics 2015-06-12 G. Foffano , D. Marenduzzo , E. Orlandini

The nonequilibrium stationary state of an exclusive genetic switch is considered. The model comprises two competing species and a single binding site which, when bound to by a protein of one species, causes the other species to be…

Statistical Mechanics · Physics 2013-01-24 J. Venegas-Ortiz , M. R. Evans