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We study the dynamics of the passage of a stiff chain through a pore into a cell containing particles that bind reversibly to it. Using Brownian Molecular Dynamics simulations we investigate the mean-first-passage time as a function of the…

Soft Condensed Matter · Physics 2009-11-10 Roya Zandi , David Reguera , Joseph Rudnick , William M. Gelbart

Kinetic of a reversible structural transition between insulating (2H) and metallic (1T') phases in a monolayer MoTe2 due to an electrostatic doping is studied using first-principle calculations. The driving force for the structural…

Materials Science · Physics 2018-06-20 O. Rubel

Designing a miniature microscale engine that can override the role of thermal fluctuations has remained elusive and is an important open challenge. Here we provide the design and theoretical framework for a unique information-based engine -…

Biological Physics · Physics 2025-12-04 Suraj Deshmukh , Sougata Guha , Basudha Roy , Shivprasad Patil , Arnab Saha , Sudipto Muhuri

Non-linear dynamical systems represent a compact, flexible, and robust tool for reactive motion generation. The effectiveness of dynamical systems relies on their ability to accurately represent stable motions. Several approaches have been…

Robotics · Computer Science 2020-06-01 Matteo Saveriano

Biomolecular machines consume free energy to break symmetry and make directed progress. Nonequilibrium ATP concentrations are the typical free energy source, with one cycle of a molecular machine consuming a certain number of ATP, providing…

Statistical Mechanics · Physics 2017-10-23 Aidan I Brown , David A Sivak

We propose a dynamical theory of how the chemical energy stored in a battery generates the electromotive force (emf). In this picture, the battery's half-cell acts as an engine, cyclically extracting work from its underlying chemical…

Chemical Physics · Physics 2021-04-23 Robert Alicki , David Gelbwaser-Klimovsky , Alejandro Jenkins , Elizabeth von Hauff

We study the dynamic properties of a thermal autonomous machine made up of two quantum Brownian particles, each of which is in contact with an environment at different temperature and moves on a periodic sinusoidal track. When such tracks…

Quantum Physics · Physics 2019-11-06 Michael Drewsen , Alberto Imparato

We consider several multiscale-in-time kinetic Monte Carlo models, in which some variables evolve on a fast time scale, while the others evolve on a slow time scale. In the first two models we consider, a particle evolves in a…

Probability · Mathematics 2015-06-12 Salma Lahbabi , Frederic Legoll

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

To address the large gap between time scales that can be easily reached by molecular simulations and those required to understand protein dynamics, we propose a rapid self-consistent approximation of the side chain free energy at every…

Biomolecules · Quantitative Biology 2017-09-15 John M. Jumper , Karl F. Freed , Tobin R. Sosnick

Protein dynamics underlie many biological functions, yet remain difficult to characterize due to the high computational cost of molecular dynamics simulations and the scarcity of dynamic structural data. This survey reviews recent advances…

Biomolecules · Quantitative Biology 2026-04-29 Haocheng Tang , Liang Shi , Ya-Shi Zhang , Xixian Liu , Jian Tang , Jiarui Lu

We introduce a method of exploring potential energy contours in complex dynamical systems based on potentiostatic kinematics wherein the systems are evolved with minimal changes to their potential energy. We construct a simple iterative…

Computational Physics · Physics 2022-04-13 Michael J. Waters , James M. Rondinelli

Maintaining energy balance and economical operation is significant for multi-energy systems such as the energy hub. However, it is usually challenged by the frequently changing and unpredictable uncertainties at different timescales. Under…

Computational Engineering, Finance, and Science · Computer Science 2022-03-03 Jiaxin Cao , Bo Yang , Shanying Zhu , Chi Yung Chung , Xinping Guan

The pervasive phenomenon of friction has been studied at the nanoscale by controlled manipulation of single atoms and molecules, which permitted a precise determination of the static friction force necessary to initiate motion. However,…

Mesoscale and Nanoscale Physics · Physics 2023-10-04 Norio Okabayashi , Thomas Frederiksen , Alexander Liebig , Franz J. Giessibl

Thermal machines are physical systems designed to convert thermal energy into practical work through cyclic state transformations. A key component in such a machine is a clock-equipped control element that dictates which interaction…

Molecular machines composed of coupled subsystems transduce free energy between different external reservoirs, in the process internally transducing energy and information. While subsystem efficiencies of these molecular machines have been…

Statistical Mechanics · Physics 2023-05-23 Matthew P. Leighton , David A. Sivak

By converting energy into mechanical work, engines play a central role in most biological and technological processes. In particular, within the current trend towards the development of nanoscience and nanotechnology, microscopic engines…

Soft Condensed Matter · Physics 2018-02-14 Falko Schmidt , Alessandro Magazzu , Agnese Callegari , Luca Biancofiore , Frank Cichos , Giovanni Volpe

In this study, we examine the dynamics of a one-dimensional Frenkel-Kontorova chain consisting of nanosize clusters (the ''particles'') and photochromic molecules (the ''bonds''), and being subjected to a periodic substrate potential.…

Materials Science · Physics 2009-11-07 Bambi Hu , Jian-Yang Zhu

Inspired by recent experiments on the dynamics of particles and polymers in artificial cytoskeletons and in cells, we introduce a modified Langevin equation for a particle in an environment that is a viscoelastic medium and that is brought…

Soft Condensed Matter · Physics 2016-11-08 Hans Vandebroek , Carlo Vanderzande

Conventional kinesin is a two-headed homodimeric motor protein, which is able to walk along microtubules processively by hydrolyzing ATP. Its neck linkers, which connect the two motor domains and can undergo a docking/undocking transition,…

Biomolecules · Quantitative Biology 2015-05-27 András Czövek , Gergely J Szöllősi , Imre Derényi