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We describe a simple ansatz to approximate the low temperature behavior of proteins and peptides by a mean-field-like model which is analytically solvable. For a small peptide some thermodynamic quantities are calculated and compared with…

Condensed Matter · Physics 2015-06-25 Ulrich H. E. Hansmann , Philippe de Forcrand

We present a statistical mechanics approach to the protein folding problem. We first review some of the basic properties of proteins, and introduce some physical models to describe their thermodynamics. These models rely on a random…

Disordered Systems and Neural Networks · Physics 2008-02-03 T. Garel , H. Orland , E. Pitard

This article describes our hypothesis on how transmutations may be induced by solid state effects in a crystalline lattice. We discuss the chemical reaction case, our extension to the nuclear binding case, and a tri-body model of a heavy…

Nuclear Theory · Physics 2020-08-14 Anthony Zuppero , Thomas J. Dolan

We report that binary dispersions of like-charged colloidal particles with large charge asymmetry but similar size exhibit phase separation into crystal and fluid phases under very low salt conditions. This is unexpected because the…

Soft Condensed Matter · Physics 2017-12-27 Koki Yoshizawa , Nao Wakabayashi , Masakatsu Yonese , Junpei Yamanaka , C. Patrick Royall

In multi-resolution simulations, different system components are simultaneously modelled at different levels of resolution, these being smoothly coupled together. In the case of enzyme systems, computationally expensive atomistic detail is…

Biological Physics · Physics 2016-11-03 Aoife C. Fogarty , Raffaello Potestio , Kurt Kremer

We present a kinetic model of crystal growth of polymers of finite molecular weight. Experiments help to classify polymer crystallization broadly into two kinetic regimes. One is observed in melts or in high molar mass polymer solutions and…

Soft Condensed Matter · Physics 2009-11-11 Arindam Kundagrami , M. Muthukumar

Theories of solvation free energies often involve electrostatic potentials at the position of a solute charge. Simulation calculations that apply cutoffs and periodic boundary conditions based on molecular centers result in center-dependent…

Chemical Physics · Physics 2008-02-03 Gerhard Hummer , Lawrence R. Pratt , Angel E. Garcia , Bruce J. Berne , Steven W. Rick

Rigidity analysis using the "pebble game" can usefully be applied to protein crystal structures to obtain information on protein folding, assembly and the structure-function relationship. However, previous work using this technique has not…

Molecular Networks · Quantitative Biology 2009-09-25 Stephen A. Wells , J. Emilio Jimenez-Roldan , Rudolf A. Römer

The folding of biological macromolecules is a fundamental process of which we lack a full comprehension. Mostly studied in proteins and RNA, single-stranded DNA (ssDNA) also folds, at physiological salt conditions, by forming non-specific…

Soft Condensed Matter · Physics 2021-09-23 X. Viader Godoy , C. R. Pulido , B. Ibarra , M. Manosas , F. Ritort

Electrostatic properties and stability of charged virus-like nano-shells are examined in ionic solutions with monovalent and multivalent ions. A theoretical model based on a thin charged spherical shell and multivalent ions within the…

Soft Condensed Matter · Physics 2015-06-12 Leili Javidpour , Anže Lošdorfer Božič , Ali Naji , Rudolf Podgornik

We study the spontaneous charging and the crystallization of spherical micron-sized water-droplets dispersed in oil by numerically solving, within a Poisson-Boltzmann theory in the geometry of a spherical cell, for the density profiles of…

Soft Condensed Matter · Physics 2013-06-06 Joost de Graaf , Jos Zwanikken , Markus Bier , Arjen Baarsma , Yasha Oloumi , Mischa Spelt , Rene van Roij

Cell polarization plays a central role in the development of complex organisms. It has been recently shown that cell polarization may follow from the proximity to a phase separation instability in a bistable network of chemical reactions.…

Statistical Mechanics · Physics 2009-03-24 A. Gamba , I. Kolokolov , V. Lebedev , G. Ortenzi

We develop a thermodynamic description of particles held at a fixed surface potential. This system is of particular interest in view of the continuing controversy over the possibility of a fluid-fluid phase separation in aqueous colloidal…

Soft Condensed Matter · Physics 2009-11-10 Yan Levin , Emmanuel Trizac , Lyderic Bocquet

Polarization properties of the photons emitted in the two-photon decay of hydrogen-like ions are studied within the framework of the density matrix and second-order perturbation theory. In particular, we derive the polarization correlation…

Atomic Physics · Physics 2011-08-23 Filippo Fratini , Andrey Surzhykov

Correlated anion and cation motion can significantly reduce the overall ion conductivity in electrolytes versus the ideal conductivity calculated based on the diffusion constants alone. Using coarse-grained molecular dynamics simulations,…

Soft Condensed Matter · Physics 2020-06-01 Kuan-Hsuan Shen , Lisa M. Hall

We use Small Angle Neutron Scattering (SANS), with an original analysis method, to obtain both the characteristic sizes and the inner composition of lysozyme-pectin complexes depending on the charge density. Lysozyme is a globular protein…

Soft Condensed Matter · Physics 2010-05-11 Isabelle Schmidt , Fabrice Cousin , Christophe Huchon , François Boué , Monique A. V. Axelos

Predicting protein secondary structure using lattice model is one of the most studied computational problem in bioinformatics. Here secondary structure or three dimensional structure of protein is predicted from its amino acid sequence.…

Computational Engineering, Finance, and Science · Computer Science 2014-07-18 Dipan Lal Shaw , M. Sohel Rahman , A. S. M. Sohidull Islam , Shuvasish Karmaker

Salt crystallization is a major cause of weathering of artworks, monuments and rocks. Damage will occur if crystals continue to grow in confinement, i.e. within the pore space of these materials generating mechanical stresses. We report on…

Materials Science · Physics 2016-01-26 Julie Desarnaud , Daniel Bonn , Noushine Shahidzadeh

Freezing of charged colloids on square or triangular two-dimensional periodic substrates has been recently shown to realize a rich variety of orientational orders. We propose a theoretical framework to analyze the corresponding structures.…

Statistical Mechanics · Physics 2009-11-10 R. Agra , F. van Wijland , E. Trizac

It has been shown that to calculate the parameters of the electrostatic field of the ion crystal lattice it sufficient to take into account ions located at a distance of 1-2 lattice spacings. More distant ions make insignificant…

General Physics · Physics 2010-01-26 Alexander Ivanchin
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