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The macroscopic curvature of double helical DNA induced by regularly repeated adenine tracts is well-known but still puzzling. Its physical origin remains controversial even though it is perhaps the best-documented sequence modulation of…

Biological Physics · Physics 2007-05-23 Alexey K. Mazur , Dimitri E. Kamashev

Charge diffusion through desoxyribonucleic acid (DNA) is a physico-chemical phenomenon that on the one hand is being explored for technological purposes, on the other hand is applied by nature for various informational processes in life.…

Biological Physics · Physics 2024-07-22 Mirko Rossini , Ole Ammerpohl , Reiner Siebert , Joachim Ankerhold

DNA has a well-defined structural transition -- the denaturation of its double-stranded form into two single strands -- that strongly affects its thermal transport properties. We show that, according to a widely implemented model for DNA…

Soft Condensed Matter · Physics 2013-02-12 Chih-Chun Chien , Kirill A. Velizhanin , Yonatan Dubi , Michael Zwolak

We consider a prototype polyene chain: donor-$\pi$(bridge)-acceptor. The distance between the donor and the acceptor is varied by increasing the number of bridged atoms and rate of electron transfer, k$_{et}$ is studied for a series of…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 S. Lakshmi , Ayan Datta , Swapan K. Pati

The Poland-Scheraga model for DNA denaturation, besides playing a central role in applications, has been widely studied in the physical and mathematical literature over the past decades. More recently a natural generalization has been…

Probability · Mathematics 2017-03-31 Quentin Berger , Giambattista Giacomin , Maha Khatib

We study the structural transition from `B' form of DNA to 'A' form of DNA using group theoretic methods. The transition is not of the order-disorder type and hence to construct a Landau kind of theory for the transition we define a higher…

Statistical Mechanics · Physics 2015-05-18 Devashish Sanyal

In order to interpret recent experimental studies of the dependence of conductance of ds-DNA as the DNA is pulled from the 3'end1-3'end2 ends, which find a sharp conductance jump for a very short (4.5 %) stretching length, we carried out…

Soft Condensed Matter · Physics 2016-08-26 Saientan Bag , Santosh Mogurampelly , William A Goddard , Prabal K Maiti

A theory of the unzipping of double-stranded (ds) DNA is presented, and is compared to recent micromanipulation experiments. It is shown that the interactions which stabilize the double helix and the elastic rigidity of single strands (ss)…

Statistical Mechanics · Physics 2009-11-07 S. Cocco , R. Monasson , J. Marko

Finding a theoretical formula for the persistence length of polyelectrolytes for the whole experimental range of salt concentration is a long standing challenge. Using the Tethered Particle Motion technique, the double-stranded DNA…

Soft Condensed Matter · Physics 2023-06-27 Manoel Manghi , Audrey Denis , Nicolas Destainville , Emmanuel Trizac , Catherine Tardin

We investigate the localization property of an electron in the disordered two-chain system (ladder model) with long-range correlation as a simple model for electronic property in DNA sequence. The chains are constructed by repetition of the…

Disordered Systems and Neural Networks · Physics 2009-11-10 Hiroaki Yamada

The denaturation of the double helix is a template for fundamental biological functions such as replication and transcription involving the formation of local fluctuational openings. The denaturation transition is studied for heterogeneous…

Biomolecules · Quantitative Biology 2014-06-03 Marco Zoli

In the demanding biosensing environment, improving selection efficiency strategies has become an issue of great significance. DNA minicircles containing between 200 and 400 base-pairs, also named microDNA, are representative of the…

Biological Physics · Physics 2018-05-14 François Sicard , Nicolas Destainville , Philippe Rousseau , Catherine Tardin , Manoel Manghi

The sequence-dependent elasticity of double-helical DNA on a nm length scale can be captured by the rigid base-pair model, whose strains are the relative position and orientation of adjacent base-pairs. Corresponding elastic potentials have…

Biomolecules · Quantitative Biology 2013-05-29 Nils B. Becker , Ralf Everaers

We calculate the equation of state of DNA under tension for the case that the DNA features loops. Such loops occur transiently during DNA condensation in the presence of multivalent ions or sliding cationic protein linkers. The…

Biomolecules · Quantitative Biology 2007-05-23 I. M. Kulic , H. Mohrbach , R. Thaokar , H. Schiessel

DNA supercoiling, the under or overwinding of DNA, is a key physical mechanism both participating to compaction of bacterial genomes and making genomic sequences adopt various structural forms. DNA supercoiling may lead to the formation of…

Biological Physics · Physics 2019-06-26 Thibaut Lepage , Ivan Junier

The statistical mechanics of DNA denaturation under fixed linking number is qualitatively different from that of the unconstrained DNA. Quantitatively different melting scenarios are reached from two alternative assumptions, namely, that…

Statistical Mechanics · Physics 2015-08-06 Alkan Kabakcioglu , Amir Bar , David Mukamel

We reply to the recent Comment [cond-mat/9702231] by J.-M. Duan. Our point of view is markedly different on every issue raised. Much of the disagreement can be traced to a different preception of experimentally relevant length scales. i) We…

Superconductivity · Physics 2016-08-15 Andrei D. Zaikin , Dmitrii S. Golubev , Anne van Otterlo , Gergely T. Zimányi

DNA migration in topologically structured microchannels with periodic cavities is investigated experimentally and with Brownian dynamics simulations of a simple bead-spring model. The results are in very good agreement with one another. In…

Biological Physics · Physics 2009-11-10 Martin Streek , Friederike Schmid , Thanh Tu Duong , Dario Anselmetti , Alexandra Ros

A detailed description of the conformational plasticity of double stranded DNA (ds) is a necessary framework for understanding protein-DNA interactions. Until now, however structure and kinetics of the transition from the basic conformation…

Soft Condensed Matter · Physics 2011-03-04 Pasquale Bianco , Lorenzo Bongini , Luca Melli , Mario Dolfi , Vincenzo Lombardi

The denaturation of double-stranded DNA as function of force and temperature is discussed. At room temperature, sequence heterogeneity dominates the physics of single molecule force-extension curves starting about 7 piconewtons of below a…

Condensed Matter · Physics 2007-05-23 David R. Nelson
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