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The entropy loss due to the formation of one or multiple loops in circular and linear DNA chains is calculated from a scaling approach in the limit of long chain segments. The analytical results allow to obtain a fast estimate for the…

Statistical Mechanics · Physics 2009-11-07 Andreas Hanke , Ralf Metzler

Double stranded DNA chain is known to have nontrivial elasticity. We study the effect of this elasticity on the denaturation profile of DNA oligomer by constraining one base pair at one end of the oligomer to remain in unstretched (or…

Soft Condensed Matter · Physics 2007-05-23 Navin Singh , Yashwant Singh

Extreme deformations of the DNA double helix attracted a lot of attention during the past decades. Particularly, the determination of the persistence length of DNA with extreme local disruptions, or kinks, has become a crucial problem in…

Biological Physics · Physics 2018-10-30 Kyryło A. Simonov

The denaturation dynamics of a long double-stranded DNA is studied by means of a model of the Poland-Scheraga type. We note that the linking of the two strands is a locally conserved quantity, hence we introduce local updates that respect…

Statistical Mechanics · Physics 2009-01-28 Marco Baiesi , Roberto Livi

A lattice model of RNA denaturation which fully accounts for the excluded volume effects among nucleotides is proposed. A numerical study shows that interactions forming pseudoknots must be included in order to get a sharp continuous…

Soft Condensed Matter · Physics 2007-05-23 M. Baiesi , E. Orlandini , A. L. Stella

The influence of decoherence and bonding on the linear conductance of single double-stranded DNA molecules is examined by fitting a phenomenological statistical model developed recently (EPJB {\bf 68}, 237 (2009)) to experimental results.…

Soft Condensed Matter · Physics 2010-09-30 M. Zilly , O. Ujsaghy , D. E. Wolf

Recent experiments [J. van Mameren et al. PNAS 106, 18231 (2009)] provide a detailed spatial picture of overstretched DNA, showing that under certain conditions the two strands of the double helix separate at about 65 pN. It was proposed…

Soft Condensed Matter · Physics 2011-03-14 Stephen Whitelam , Phillip L. Geissler , Sander Pronk

The experiment that the high spin selectivity and the length-dependent spin polarization are observed in double-stranded DNA [Science ${\bf 331}$, 894 (2011)], is elucidated by considering the combination of the spin-orbit coupling, the…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ai-Min Guo , Qing-feng Sun

We study electronic transport in long DNA chains using the tight-binding approach for a ladder-like model of DNA. We find insulating behavior with localizaton lengths xi ~ 25 in units of average base-pair seperation. Furthermore, we observe…

Soft Condensed Matter · Physics 2007-05-23 Antonio Rodriguez , Rudolf A. Roemer , Matthew S. Turner

Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different. Taking into account long-range correlations…

Soft Condensed Matter · Physics 2015-05-14 A. A. Krokhin , V. M. K. Bagci , F. M. Izrailev , O. V. Usatenko , V. A. Yampol'skii

Most living systems rely on double-stranded DNA (dsDNA) to store their genetic information and perpetuate themselves. This biological information has been considered the main target of evolution. However, here we show that symmetries and…

Biomolecules · Quantitative Biology 2025-05-01 Piero Fariselli , Cristian Taccioli , Luca Pagani , Amos Maritan

The replacment of mutual avoidance of polymers by a long-range interaction of the type proposed by Garel etal (Europhys. Lett. 55, 132 (2001), cond-mat/0101058) is inconsistent with the prevalent renormalization group arguments.

Statistical Mechanics · Physics 2009-11-07 Somendra M. Bhattacharjee

Unbinding of a double-stranded DNA reduces to an unscreened long range interaction and maps on various problems. Heterogeneity renormalizes interaction. Renormalization is temperature dependent. At an unbinding transition it approaches…

Statistical Mechanics · Physics 2007-05-23 Mark Ya. Azbel'

Using Brownian dynamics simulations, we study the migration of long charged chains in an electrophoretic microchannel device consisting of an array of microscopic entropic traps with alternating deep regions and narrow constrictions. Such a…

Biological Physics · Physics 2007-05-23 Martin Streek , Friederike Schmid , Thanh Tu Duong , Alexandra Ros

Charge transfer in a DNA duplex chain is studied by constructing a system with virtual electrodes connected at the ends of each DNA strand. The systeym is described by the tight-binding model and its transport is analyzed by the transfer…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 X. F. Wang , Tapash Chakraborty

Chain-like macromolecules in solution, whether biological or synthetic, transform from a spatially extended conformation to a compact one upon change of temperature or solvent qualities. This sharp transition plays a key role in various…

Soft Condensed Matter · Physics 2007-05-23 H. Diamant , D. Andelman

The chiral nature of DNA plays a crucial role in cellular processes. Here we use magnetic tweezers to explore one of the signatures of this chirality, the coupling between stretch and twist deformations. We show that the extension of a…

Biomolecules · Quantitative Biology 2009-09-29 Timothee Lionnet , Sylvain Joubaud , Richard Lavery , David Bensimon , Vincent Croquette

We present a short review of various experiments that measure charge transfer and charge transport in DNA. Some general comments are made on the possible connection between 'chemistry-style' charge transfer experiments that probe…

Disordered Systems and Neural Networks · Physics 2009-11-10 N. P. Armitage , M. Briman , G. Gruner

We investigate the voltage-driven transport of hybridized DNA through membrane channels. As membrane channels are typically too narrow to accommodate hybridized DNA, the dehybridization of the DNA is the critical rate limiting step in the…

Statistical Mechanics · Physics 2007-05-23 G. Lakatos , T. Chou , B. Bergersen , G. Patey

A theory is presented of DNA hairpins enclosed in a nanochannel. A hairpin becomes constrained as it approaches the wall of a channel which leads to an entropic force causing the hairpin to tighten. The free energy of the hairpin computed…

Soft Condensed Matter · Physics 2009-11-11 Theo Odijk