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A protein residue network (PRN) is a network of interacting amino acids within a protein. We describe characteristics of a sparser, highly central and more volatile sub-network of a PRN called the short-cut network (SCN), as a protein folds…

Molecular Networks · Quantitative Biology 2015-08-13 Susan Khor

Specific protein-protein interactions are crucial in the cell, both to ensure the formation and stability of multi-protein complexes, and to enable signal transduction in various pathways. Functional interactions between proteins result in…

Biological Physics · Physics 2016-11-21 Anne-Florence Bitbol , Robert S. Dwyer , Lucy J. Colwell , Ned S. Wingreen

Evaluating accessible conformational space is computationally expensive and thermal motions are partly neglected in computer models of molecular interactions. This produces error into the estimates of binding strength. We introduce a method…

Quantitative Methods · Quantitative Biology 2016-12-13 Riku Hakulinen , Santeri Puranen

In structure-based models of proteins, one often assumes that folding is accomplished when all contacts are established. This assumption may frequently lead to a conceptual problem that folding takes place in a temperature region of very…

Biomolecules · Quantitative Biology 2016-05-23 Karol Wołek , Marek Cieplak

Improvements in technique in conjunction with an evolution of the theoretical and conceptual approach to neuronal networks provide a new perspective on living neurons in culture. Organization and connectivity are being measured…

Disordered Systems and Neural Networks · Physics 2010-08-02 Jean-Pierre Eckmann , Ofer Feinerman , Leor Gruendlinger , Elisha Moses , Jordi Soriano , Tsvi Tlusty

Mapping between sequence and structure is currently an open problem in structural biology. Despite many experimental and computational efforts it is not clear yet how the structure is encoded in the sequence. Answering this question may…

Biomolecules · Quantitative Biology 2013-10-08 Iddo Friedberg

In forced wetting, a rapidly moving surface drags with it a thin layer of trailing fluid as it is plunged into a second fluid bath. Using high-speed interferometry, we find characteristic structure in the thickness of this layer with…

Soft Condensed Matter · Physics 2019-01-16 Mengfei He , Sidney R. Nagel

The ''polymer reference interaction site model'' (PRISM) integral equation theory is used to determine the structure factor of rigid dendrimers in solution. The theory is quite successful in reproducing experimental structure factors for…

Soft Condensed Matter · Physics 2009-11-13 L. Harnau , S. Rosenfeldt , M. Ballauff

Advances in statistical learning theory present the opportunity to develop statistical models of quantum many-body systems exhibiting remarkable predictive power. The potential of such ``theory-thin'' approaches is illustrated with the…

Nuclear Theory · Physics 2008-11-26 John W. Clark , Haochen Li

Yet in spite of advances in hospital treatment, hospitals continue to be a breeding ground for several airborne diseases and for diseases that are transmitted through close contacts like SARS, methicillin-resistant Staphylococcus aureus…

Other Quantitative Biology · Quantitative Biology 2007-11-06 Fredrik Liljeros , Petter Holme , Johan Giesecke

In the course of evolution, proteins show a remarkable conservation of their three-dimensional structure and their biological function, leading to strong evolutionary constraints on the sequence variability between homologous proteins. Our…

Quantitative Methods · Quantitative Biology 2014-04-07 Carlo Baldassi , Marco Zamparo , Christoph Feinauer , Andrea Procaccini , Riccardo Zecchina , Martin Weigt , Andrea Pagnani

In this paper, we study the structure and dynamical properties of protein contact networks with respect to other biological networks, together with simulated archetypal models acting as probes. We consider both classical topological…

Biomolecules · Quantitative Biology 2015-09-04 Lorenzo Livi , Enrico Maiorino , Andrea Pinna , Alireza Sadeghian , Antonello Rizzi , Alessandro Giuliani

It has been argued that the iso-scalar and iso-vector mesons play significant roles in nuclear matter and neutron star structures. We improve the extended linear sigma model with baryons, proposed in our previous work, by introducing the…

Nuclear Theory · Physics 2025-10-07 Yao Ma , Yong-Liang Ma

Functional protein-protein interactions are crucial in most cellular processes. They enable multi-protein complexes to assemble and to remain stable, and they allow signal transduction in various pathways. Functional interactions between…

Biomolecules · Quantitative Biology 2018-11-14 Anne-Florence Bitbol

The Gene or DNA sequence in every cell does not control genetic properties on its own; Rather, this is done through translation of DNA into protein and subsequent formation of a certain 3D structure. The biological function of a protein is…

Computational Engineering, Finance, and Science · Computer Science 2019-05-30 Leila Khalatbari , Mohammad Reza Kangavari , Saeid Hosseini , Hongzhi Yin , Ngai-Man Cheung

The aim of this paper and its sequel is to introduce and classify the holonomy algebras of the projective Tractor connection. After a brief historical background, this paper presents and analyses the projective Cartan and Tractor…

Differential Geometry · Mathematics 2007-05-23 Stuart Armstrong

We present the first application of statistical spectroscopy to study the root-mean-square value of the parity nonconserving (PNC) interaction matrix element M determined experimentally by scattering longitudinally polarized neutrons from…

Nuclear Theory · Physics 2009-10-31 S. Tomsovic , Mikkel B. Johnson , A. Hayes , J. D. Bowman

The general nuclear contact matrices are defined, taking into consideration all partial waves and finite-range interactions, extending Tan's work for the zero range model. The properties of these matrices are discussed and the relations…

Nuclear Theory · Physics 2015-11-25 Ronen Weiss , Betzalel Bazak , Nir Barnea

Interactive molecular graphics applications facilitate analysis of three dimensional protein structures. Naturally, non-interactive 2-D snapshots of the protein structures do not convey the same level of geometric detail. Several 2-D…

Quantitative Methods · Quantitative Biology 2014-02-24 Francis Bell , Chunyu Zhao , Ahmet Sacan

Stochastic modeling of disease dynamics has had a long tradition. Among the first epidemic models including a spatial structure in the form of local interactions is the contact process. In this article we investigate two extensions of the…

Probability · Mathematics 2007-05-23 L. Belhadji , N. Lanchier
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