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Polymer translocation has long been a topic of interest in the field of biological physics given its relevance in both biological (protein and DNA/RNA translocation through nuclear and cell membranes) and technological processes (nanopore…

Soft Condensed Matter · Physics 2023-09-11 Alejandro Sainz-Agost , Fernando Falo , Alessandro Fiasconaro

Polymer networks formed by cross linking flexible polymer chains are ubiquitous in many natural and synthetic soft-matter systems. Current micromechanics models generally do not account for excluded volume interactions except, for instance,…

Soft Condensed Matter · Physics 2023-06-05 Pratik Khandagale , Timothy Breitzman , Carmel Majidi , Kaushik Dayal

We study by using Monte Carlo simulations the hysteresis in unzipping and rezipping of a double stranded DNA (dsDNA) by pulling its strands in opposite directions in the fixed force ensemble. The force is increased, at a constant rate from…

Soft Condensed Matter · Physics 2012-10-11 Rajeev Kapri

We consider force-induced unzipping transition for a heterogeneous DNA model with a correlated base-sequence. Both finite-range and long-range correlated situations are considered. It is shown that finite-range correlations increase…

Soft Condensed Matter · Physics 2009-11-10 A. E. Allahverdyan , Zh. S. Gevorkian , Chin-Kun Hu , Ming-Chya Wu

The force induced unzipping transition of a double stranded DNA is considered from a purely thermodynamic point of view. This analysis provides us with a set of relations that can be used to test microscopic theories and experiments. The…

Soft Condensed Matter · Physics 2015-06-18 Poulomi Sadhukhan , Somendra M. Bhattacharjee

During the life cycle of bacterial cells the non-mixing of the two ring-shaped daughter genomes is an important prerequisite for the cell division process. Mimicking the environments inside highly crowded biological cells, we study the…

Soft Condensed Matter · Physics 2014-12-24 Jaeoh Shin , Andrey G Cherstvy , Ralf Metzler

We study the unzipping of double stranded DNA (dsDNA) by applying a pulling force at a fraction $s$ $(0 \le s \le 1)$ from the anchored end. From exact analytical and numerical results, the complete phase diagram is presented. The phase…

Soft Condensed Matter · Physics 2009-11-10 Rajeev Kapri , Somendra M. Bhattacharjee , Flavio Seno

Using theory and simulations, we carried out a first systematic characterization of DNA unzipping via nanopore translocation. Starting from partially unzipped states, we found three dynamical regimes depending on the applied force, f: (i)…

Soft Condensed Matter · Physics 2023-02-08 Antonio Suma , Vincenzo Carnevale , Cristian Micheletti

We consider the phase transition induced by compressing a self-avoiding walk in a slab where the walk is attached to both walls of the slab in two and three dimensions, and the resulting phase once the polymer is compressed. The process of…

Statistical Mechanics · Physics 2025-11-19 C J Bradly , N R Beaton , A L Owczarek

In these proceedings, we first summarize some general properties of phase transitions in the presence of quenched disorder, with emphasis on the following points: the need to distinguish typical and averaged correlations, the possible…

Disordered Systems and Neural Networks · Physics 2008-03-12 Cecile Monthus , Thomas Garel

The phase diagram of unzipping of an adsorbed directed polymer in two dimensions in a random medium has been determined. Both the hard-wall and the soft-wall cases are considered. Exact solutions for the pure problem with different…

Statistical Mechanics · Physics 2009-11-11 Rajeev Kapri , Somendra M. Bhattacharjee

We examine the phase transition of polymer adsorption as well as the underlying kinetics of polymer binding from dilute solutions on a structureless solid surface. The emphasis is put on the properties of regular multiblock copolymers,…

Soft Condensed Matter · Physics 2009-09-03 A. Milchev , V. Rostiashvili , S. Bhattacharya , T. Vilgis

The strong bending of polymers is poorly understood. We propose a general quantitative framework of polymer bending that includes both the weak and strong bending regimes on the same footing, based on a single general physical principle. As…

Biological Physics · Physics 2019-12-04 Aleksander V. Drozdetski , Abhishek Mukhopadhyay , Alexey V. Onufriev

The mechanism and driving forces of chromosome segregation in the bacterial cell cycle of E. coli is one of the least understood events in its life cycle. Using principles of entropic repulsion between polymer loops confined in a cylinder,…

Soft Condensed Matter · Physics 2021-12-24 Debarshi Mitra , Shreerang Pande , Apratim Chatterji

The force-assisted desorption kinetics of a macromolecule from adhesive surface is studied theoretically, using the notion of tensile (Pincus) blobs, as well as by means of Monte-Carlo (MC) and Molecular Dynamics (MD) simulations. We show…

Soft Condensed Matter · Physics 2015-06-04 J. Paturej , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

We present a mean-field dynamical theory for single semiflexible polymers which can precisely capture, without fitting parameters, recent fluorescence correlation spectroscopy results on single monomer kinetics of DNA strands in solution.…

Soft Condensed Matter · Physics 2009-10-19 Michael Hinczewski , Roland R. Netz

We consider the dynamics of overdamped MEMS devices undergoing the pull-in instability. Numerous previous experiments and numerical simulations have shown a significant increase in the pull-in time under DC voltages close to the pull-in…

Applied Physics · Physics 2017-12-04 Michael Gomez , Derek E. Moulton , Dominic Vella

We study the effect of random forces on a double stranded DNA in unzipping the two strands, analogous to the problem of an adsorbed polymer under a random force. The ground state develops bubbles of various lengths as the random force…

Soft Condensed Matter · Physics 2007-05-23 Rajeev Kapri , Somendra M. Bhattacharjee

The unzipping of a double stranded DNA whose ends are subjected to a time dependent periodic force with frequency $\omega$ and amplitude $G$ is studied using Monte Carlo simulations. We obtain the dynamical order parameter, $Q$, defined as…

Soft Condensed Matter · Physics 2019-06-17 M. Suman Kalyan , Rajeev Kapri

Following Poland and Scheraga, we consider a simplified model for the denaturation transition of DNA. The two strands are modeled as interacting polymer chains. The attractive interactions, which mimic the pairing between the four bases,…

Soft Condensed Matter · Physics 2009-11-07 T. Garel , C. Monthus , H. Orland