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Proteins are the most important biomolecules for living organisms. The understanding of protein structure, function, dynamics and transport is one of most challenging tasks in biological science. In the present work, persistent homology is,…

Biomolecules · Quantitative Biology 2014-12-10 Kelin Xia , Guo-Wei Wei

Information security is of great importance for modern society with all things connected. Physical unclonable function (PUF) as a promising hardware primitive has been intensively studied for information security. However, the widely…

Cryptography and Security · Computer Science 2021-09-09 Yongbiao Wan , Pidong Wang , Feng Huang , Jun Yuan , Dong Li , Kun Chen , Jianbin Kang , Qian Li , Taiping Zhang , Song Sun , Zhiguang Qiu , Yao Yao

We explore optical manipulation of sculpted light based on phase dependent electromagnetically induced transparency through a five level atomic system. A transverse magnetic field (TMF) and a suitable spatially inhomogeneous control field…

Optics · Physics 2019-03-27 Sandeep Sharma , Tarak N. Dey

A novel technique was demonstrated that overcome important drawbacks to crosslink cells by irradiation with ultrashort UV laser pulses (L-crosslinking). To use this technique coupled to Chromatin ImmunoPrecipitation (ChIP) in a high…

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

Modulating the amplitude and phase of light is at the heart of many applications such as wavefront shaping, transformation optics, phased arrays, modulators and sensors. Performing this task with high efficiency and small footprint is a…

Nonlinear metasurfaces are multifunctional photonic elements that generate and control light, enabling multiple proof-of-principle applications, such as in nonlinear holography, beam shaping, and nanoscale sources of entangled photon pairs.…

Topological photonics has revolutionized our understanding of light propagation, but most of current studies are focused on designing a static photonic structure. Developing a dynamic photonic topological platform to switch multiple…

Applied Physics · Physics 2021-10-04 Jian Wei You , Qian Ma , Zhihao Lan , Qiang Xiao , Nicolae C. Panoiu , Tie Jun Cui

Advances in optical trapping design principles have led to tremendous progress in manipulating nanoparticles (NPs) with diverse functionalities in different environments using bulky systems. However, efficient control and manipulation of…

The so-called Mixed Feedback Loop (MFL) is a small two-gene network where protein A regulates the transcription of protein B and the two proteins form a heterodimer. It has been found to be statistically over-represented in statistical…

Molecular Networks · Quantitative Biology 2009-11-11 Paul Francois , Vincent Hakim

In the present paper we address the problem of the energy downconversion of the light absorbed by a protein into its internal vibrational modes. We consider the case in which the light receptors are fluorophores either naturally…

Biological Physics · Physics 2023-06-05 Elham Faraji , Roberto Franzosi , Stefano Mancini , Marco Pettini

Photochromic molecular structures constitute a unique platform for constructing molecular switches, sensors and memory devices. One of their most promising applications is as light-switchable electron acceptor or donor units. Here, we…

Chemical Physics · Physics 2020-07-21 Jakub K. Sowa , Emily A. Weiss , Tamar Seideman

The combinations of artificial intelligence and lasers provide powerful ways to form smart light sources with ground-breaking functions. Here, a Raman fiber laser (RFL) with reconfigurable and programmable spectra in an ultra-wide bandwidth…

Optics · Physics 2022-04-12 Yanli Zhang , Shanshan Wang , Mingzhu She , Weili Zhang

Neuromorphic devices have gained significant attention as potential building blocks for the next generation of computing technologies owing to their ability to emulate the functionalities of biological nervous systems. The essential…

A full density-matrix simulation is performed for optical deflection of a barium monofluoride ($^{138}$Ba$^{19}$F) beam using the bichromatic force, which employs pairs of counter-propagating laser beams that are offset in frequency. We…

Atomic Physics · Physics 2023-07-26 A. Marsman , M. Horbatsch , E. A. Hessels

Using a first principles approach, we study the electron transport properties of a new class of molecular wires containing fluorenone units, whose features open up new possibilities for controlling transport through a single molecule. We…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 C. J. Lambert , I. M. Grace , T. Papadopoulos

We describe the effect of optical aberrations on fluorescence fluctuations microscopy (FFM), when focusing through a single living cell. FFM measurements are performed in an aqueous fluorescent solution and prove to be a highly sensitive…

Biological Physics · Physics 2014-03-13 Charles-Edouard Leroux , Alexei Grichine , Irène Wang , Antoine Delon

Purple membranes from the archaeon Halobacterium salinarum consist of two-dimensional crystals of the light-driven proton pump bacteriorhodopsin, which convert photons into a proton gradient across the cell membrane. This functional feature…

We demonstrate experimentally a method of varying the degree of directionality in laser-induced molecular rotation. To control the ratio between the number of clockwise and counter-clockwise rotating molecules (with respect to a fixed…

Chemical Physics · Physics 2021-05-05 Alexander A. Milner , Valery Milner

Natural Killer (NK) cell activation is dynamically regulated by numerous activating and inhibitory surface receptors that accumulate at the immune synapse. Quantitative analysis of receptor dynamics has been limited by methodologies which…

Cell Behavior · Quantitative Biology 2015-06-17 Sophie V. Pageon , Gerardo Aquino , Kathryn Lagrue , Karsten Köhler , Robert G. Endres , Daniel M. Davis