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Fitness landscapes are a useful concept to study the dynamics of meta-heuristics. In the last two decades, they have been applied with success to estimate the optimization power of several types of evolutionary algorithms, including genetic…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Nuno M. Rodrigues , Sara Silva , Leonardo Vanneschi

This paper is concerned with the evolution of haploid organisms that reproduce asexually. In a seminal piece of work, Eigen and coauthors proposed the quasispecies model in an attempt to understand such an evolutionary process. Their work…

Populations and Evolution · Quantitative Biology 2012-03-07 Narendra M. Dixit , Piyush Srivastava , Nisheeth K. Vishnoi

After an introduction to the general topic of models for a given locus of a diploid population whose quadratic dynamics is determined by a fitness landscape, we consider more specifically the models that can be treated using genetic (or…

Populations and Evolution · Quantitative Biology 2016-07-08 Nicolas Grosjean , Thierry Huillet , Geneviève Rollet

We study the long-time behaviour of phenotype-structured models describing the evolutionary dynamics of asexual species whose phenotypic fitness landscape is characterised by multiple peaks. First we consider the case where phenotypic…

Analysis of PDEs · Mathematics 2020-10-28 Tommaso Lorenzi , Camille Pouchol

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Evolution on neutral networks of genotypes has been found in models to concentrate on genotypes with high mutational robustness, to a degree determined by the topology of the network. Here analysis is generalized beyond neutral networks to…

Populations and Evolution · Quantitative Biology 2015-09-01 Lee Altenberg

We study evolution equations on networks that can be modeled by means of hyperbolic systems. We extend our previous findings in \cite{KraMugNic20} by discussing well-posedness under rather general transmission conditions that might be…

Analysis of PDEs · Mathematics 2020-07-17 Marjeta Kramar Fijavž , Delio Mugnolo , Serge Nicaise

We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutuation rate limit, which we model as a biased Langevin process in the genotype space. We show analytically and numerically that, if the fitness…

Populations and Evolution · Quantitative Biology 2014-02-04 Jakub Otwinowski , Sorin Tanase-Nicola , Ilya Nemenman

The $NK$ model, introduced by Kauffman, Levin, and Weinberger, is a random field used to describe the fitness landscape of certain species with $N$ genetic loci, each interacting with $K$ others. The model has wide applications in…

Probability · Mathematics 2025-08-19 Wei-Kuo Chen , Si Tang

One of the key problems related to the Bak-Sneppen evolution model on the circle is to compute the limit distribution of the fitness at a fixed observation vertex in the stationary regime, as the size of the system tends to infinity.…

Disordered Systems and Neural Networks · Physics 2007-05-23 R. Meester , D. Znamenski

Many important real-world networks manifest "small-world" properties such as scale-free degree distributions, small diameters, and clustering. The most common model of growth for these networks is "preferential attachment", where nodes…

Quantitative Methods · Quantitative Biology 2009-11-13 Samarth Swarup , Les Gasser

Phase field evolutions are obtained by means of time discrete schemes, providing (or selecting) at each time step an equilibrium configuration of the system, which is usually computed by descent methods for the free energy (e.g.staggered…

Analysis of PDEs · Mathematics 2025-02-17 Eleonora Maggiorelli , Matteo Negri

The parallel mutation-selection evolutionary dynamics, in which mutation and replication are independent events, is solved exactly in the case that the Malthusian fitnesses associated to the genomes are described by the Random Energy Model…

Biological Physics · Physics 2009-10-14 David B. Saakian , José F. Fontanari

We study the probabilistic evolution of a birth and death continuous time measure-valued process with mutations and ecological interactions. The individuals are characterized by (phenotypic) traits that take values in a compact metric…

Probability · Mathematics 2009-04-23 Pierre Collet , Servet Martinez , Sylvie Méléard , Jaime San Martin

This work presents a population genetic model of evolution, which includes haploid selection, mutation, recombination, and drift. The mutation-selection equilibrium can be expressed exactly in closed form for arbitrary fitness functions…

Populations and Evolution · Quantitative Biology 2023-02-28 Jenny M. Poulton , Lee Altenberg , Chris Watkins

Proteins evolve through complex sequence spaces, with fitness landscapes serving as a conceptual framework that links sequence to function. Fitness landscapes can be smooth, where multiple similarly accessible evolutionary paths are…

Populations and Evolution · Quantitative Biology 2024-11-21 Mahakaran Sandhu , John Chen , Dana Matthews , Matthew A Spence , Sacha B Pulsford , Barnabas Gall , James Nichols , Nobuhiko Tokuriki , Colin J Jackson

The mean field limit for systems of many fermions is naturally coupled with a semiclassical limit. This makes the analysis of the mean field regime much more involved, compared with bosonic systems. In this paper, we study the dynamics of…

Mathematical Physics · Physics 2015-06-15 Niels Benedikter , Marcello Porta , Benjamin Schlein

Evolutionary dynamics is often viewed as a subtle process of change accumulation that causes a divergence among organisms and their genomes. However, this interpretation is an inheritance of a gradualistic view that has been challenged at…

Populations and Evolution · Quantitative Biology 2018-07-27 Jacobo Aguirre , Pablo Catalán , José A. Cuesta , Susanna Manrubia

A population evolving in an inhomogeneous environment will adapt differently to different regions. We study the conditions under which such a population can maintain adaptations to a particular region when that region is not stationary, but…

Populations and Evolution · Quantitative Biology 2007-05-23 Michael M. Desai , David R. Nelson

We study adaptation of a haploid asexual population on a fitness landscape defined over binary genotype sequences of length $L$. We consider greedy adaptive walks in which the population moves to the fittest among all single mutant…

Populations and Evolution · Quantitative Biology 2016-03-21 Su-Chan Park , Johannes Neidhart , Joachim Krug