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It often is emphasized that gene expression is noisy. A seemingly contradictory view is that control mechanisms have been optimized to squeeze as much information as possible out of a limited number of molecules. Here we revisit these…

Biological Physics · Physics 2025-12-17 Nicholas Lawson , William Bialek

Precortical neural systems encode information collected by the senses, but the driving principles of the encoding used have remained a subject of debate. We present a model of retinal coding that is based on three constraints: information…

Neurons and Cognition · Quantitative Biology 2016-04-08 Honghao Shan , Matthew H. Tong , Garrison W. Cottrell

Over repeat presentations of the same stimulus, sensory neurons show variable responses. This "noise" is typically correlated between pairs of cells, and a question with rich history in neuroscience is how these noise correlations impact…

Neurons and Cognition · Quantitative Biology 2015-06-16 Yu Hu , Joel Zylberberg , Eric Shea-Brown

Intercellular signaling has an important role in organism development, but not all communication occurs using the same mechanism. Here, we analyze the energy efficiency of intercellular signaling by two canonical mechanisms: diffusion of…

Quantitative Methods · Quantitative Biology 2022-11-30 Hyunjoong Kim , Yoichiro Mori , Joshua B. Plotkin

Neurons process sensory stimuli efficiently, showing sparse yet highly variable ensemble spiking activity involving structured higher-order interactions. Notably, while neural populations are mostly silent, they occasionally exhibit highly…

Neurons and Cognition · Quantitative Biology 2025-07-17 Ulises Rodríguez-Domínguez , Hideaki Shimazaki

In the field of interactive coding, two or more parties wish to carry out a distributed computation over a communication network that may be noisy. The ultimate goal is to develop efficient coding schemes that can tolerate a high level of…

Data Structures and Algorithms · Computer Science 2022-08-04 Ran Gelles , Yael T. Kalai , Govind Ramnarayan

Intelligent and low-power retinal prostheses are highly demanded in this era, where wearable and implantable devices are used for numerous healthcare applications. In this paper, we propose an energy-efficient dynamic scenes processing…

Neural and Evolutionary Computing · Computer Science 2022-09-19 Chuanqing Wang , Chaoming Fang , Yong Zou , Jie Yang , Mohamad Sawan

In this correspondence information theoretical tools are used to investigate the statistical properties of modeled cochlear nucleus globular bushy cell spike trains. The firing patterns are obtained from a simulation software that generates…

Neurons and Cognition · Quantitative Biology 2012-04-25 Andrea Grigorescu , Marek Rudnicki , Michael Isik , Werner Hemmert , Stefano Rini

Reducing energy consumption is a critical point for neural network models running on edge devices. In this regard, reducing the number of multiply-accumulate (MAC) operations of Deep Neural Networks (DNNs) running on edge hardware…

Neural and Evolutionary Computing · Computer Science 2022-04-05 Simon Narduzzi , Siavash A. Bigdeli , Shih-Chii Liu , L. Andrea Dunbar

Spiking Neural Networks (SNNs) offer energy-efficient and biologically plausible alternatives to traditional artificial neural networks, but their performance depends critically on the tuning of neuron model parameters. In this work, we…

Neural and Evolutionary Computing · Computer Science 2025-07-22 Szymon Mazurek , Jakub Caputa , Maciej Wielgosz

Random linear network coding (RLNC) is asymptotically throughput optimal in the wireless broadcast of a block of packets from a sender to a set of receivers, but suffers from heavy computational load and packet decoding delay. To mitigate…

Information Theory · Computer Science 2015-06-04 Mingchao Yu , Parastoo Sadeghi , Alex Sprintson

The interference management technique that treats interference as noise (TIN) is optimal when the interference is sufficiently low. Scheduling algorithms based on the TIN optimality condition have recently been proposed, e.g., for…

Information Theory · Computer Science 2018-07-03 Mudasar Bacha , Marco Di Renzo , Bruno Clerckx

By recording multiple cells simultaneously, electrophysiologists have found evidence for repeating spatiotemporal spike patterns, which can carry information. How this information is extracted by downstream neurons is unclear. In this…

Neural and Evolutionary Computing · Computer Science 2017-07-05 Timothée Masquelier

Positive correlations in the activity of neurons are widely observed in the brain. Previous studies have shown these correlations to be detrimental to the fidelity of population codes or at best marginally favorable compared to independent…

Neurons and Cognition · Quantitative Biology 2013-07-22 Rava Azeredo da Silveira , Michael J. Berry

We consider the problem of determining the power ratio between the training symbols and data symbols in order to maximize the channel capacity for transmission over uncertain channels with a channel estimate available at both the…

Information Theory · Computer Science 2015-05-13 Ather Gattami

Neural populations encode information about their stimulus in a collective fashion, by joint activity patterns of spiking and silence. A full account of this mapping from stimulus to neural activity is given by the conditional probability…

Neurons and Cognition · Quantitative Biology 2013-06-14 Einat Granot-Atedgi , Gašper Tkačik , Ronen Segev , Elad Schneidman

Reconfigurable intelligent surface (RIS) is a promising solution to deal with the blockage-sensitivity of millimeter wave band and reduce the high energy consumption caused by network densification. However, deploying large scale RISs may…

Information Theory · Computer Science 2024-02-12 Yining Xu , Sheng Zhou

Cellular behaviors such as migration, division, and differentiation rely on precise timing, and yet the molecular events that govern these behaviors are highly stochastic. We investigate regulatory strategies that decrease the timing noise…

Biological Physics · Physics 2020-07-01 Shivam Gupta , Sean Fancher , Hendrik C. Korswagen , Andrew Mugler

Random linear network coding (RLNC) has been shown to efficiently improve the network performance in terms of reducing transmission delays and increasing the throughput in broadcast and multicast communications. However, it can result in…

Systems and Control · Computer Science 2016-10-25 Emmanouil Skevakis , Ioannis Lambadaris

During mammalian development the cerebral metabolic rate correlates qualitatively with synaptogenesis, and both often exhibit bimodal temporal profiles. Despite these non-monotonic dependencies, it is found based on empirical data for…

Neurons and Cognition · Quantitative Biology 2012-04-19 Jan Karbowski
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