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We calculate bubble nucleation rates in a Lennard-Jones fluid through explicit molecular dynamics simulations. Our approach -- based on a recent free energy method (dubbed reweighted Jarzynski sampling), transition state theory, and a…

Soft Condensed Matter · Physics 2022-11-16 Kristof M. Bal , Erik C. Neyts

We analyze a modification of the Richards growth model by introducing a time-dependent perturbation in the growth rate. This modification becomes effective at a special switching time, which represents the first-crossing-time of the…

Applications · Statistics 2024-10-31 Antonio Di Crescenzo , Paola Paraggio , Francisco Torres-Ruiz

Calculating relative free energies is a topic of substantial interest and has many applications including solvation and binding free energies, which are used in computational drug discovery. However, there remain the challenges of accuracy,…

Chemical Physics · Physics 2016-09-28 Asaf Farhi , Bipin Singh

We study the problem of stabilization for a class of evolution systems with fractional-damping. After writing the equations as an augmented system we prove in this article first that the problem is well posed. Second, using the LaSalle's…

Analysis of PDEs · Mathematics 2020-10-20 Kaïs Ammari , Fathi Hassine , Luc Robbiano

Adiabatic processes are important for studying the dynamics of a time-dependent system. Conventionally, the adiabatic processes can only be achieved by varying the system slowly. We speed up both classical and quantum adiabatic processes by…

Quantum Physics · Physics 2013-05-21 Jia-wen Deng , Qing-hai Wang , Jiangbin Gong

Generative models are a promising tool to address the sampling problem in multi-body and condensed-matter systems in the framework of statistical mechanics. In this work, we show that normalizing flows can be used to learn a transformation…

Computational Physics · Physics 2022-08-23 Alessandro Coretti , Sebastian Falkner , Phillip Geissler , Christoph Dellago

We propose a new method to efficiently compute load-flows (the steady-state of the power-grid for given productions, consumptions and grid topology), substituting conventional simulators based on differential equation solvers. We use a deep…

Machine Learning · Statistics 2018-01-31 Benjamin Donnot , Isabelle Guyon , Marc Schoenauer , Antoine Marot , Patrick Panciatici

We analyse a non-local parabolic integro-differential equation modelling the evolutionary dynamics of a phenotypically-structured population in a changing environment. Such models arise in a variety of contexts from climate change to…

Analysis of PDEs · Mathematics 2024-07-16 Manh Hong Duong , Fabian Spill , Blaine van Rensburg

This article describes nonequilibrium techniques for the calculation of free energies of solids using molecular dynamics (MD) simulations. These methods provide an alternative to standard equilibrium thermodynamic integration methods and…

Materials Science · Physics 2022-01-13 Rodrigo Freitas , Mark Asta , Maurice de Koning

In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…

Analysis of PDEs · Mathematics 2021-08-31 Xu'an Dou , Jian-Guo Liu , Zhennan Zhou

Predicting turbulent flame speed (the large time front speed) is a fundamental problem in turbulent combustion theory. Several models have been proposed to study the turbulent flame speed, such as the G-equations, the F-equations…

Analysis of PDEs · Mathematics 2011-05-30 Jack Xin , Yifeng Yu

We performed molecular dynamics simulations to study relaxation phenomena during vapor-liquid transitions in a single component Lennard-Jones system. Results from two different overall densities are presented; one in the neighborhood of the…

Statistical Mechanics · Physics 2019-06-04 Sutapa Roy , Arabinda Bera , Suman Majumder , Subir K. Das

Via a combination of molecular dynamics (MD) simulations and finite-size scaling (FSS) analysis, we study dynamic critical phenomena for the vapor-liquid transition in a three dimensional Lennard-Jones system. The phase behavior of the…

Statistical Mechanics · Physics 2017-08-18 Jiarul Midya , Subir K. Das

We have developed a new simulation algorithm for free-energy calculations. The method is a multidimensional extension of the replica-exchange method. While pairs of replicas with different temperatures are exchanged during the simulation in…

Statistical Mechanics · Physics 2009-10-31 Yuji Sugita , Akio Kitao , Yuko Okamoto

The work fluctuations of an oscillator in contact with a heat reservoir and driven out of equilibrium by an external force are studied experimentally. The oscillator dynamics is modeled by a Langevin equation. We find both experimentally…

Statistical Mechanics · Physics 2009-11-11 Frederic Douarche , Sergio Ciliberto , Artem Petrosyan

We study by computer simulation the nucleation of a supersaturated Lennard-Jones vapor into the liquid phase. The large free energy barriers to transition make the time scale of this process impossible to study by ordinary molecular…

Statistical Mechanics · Physics 2018-08-15 Pablo M. Piaggi , Omar Valsson , Michele Parrinello

The ability to separate and analyze chemical species with high resolution, sensitivity, and throughput is central to the development of microfluidics systems. Deterministic lateral displacement (DLD) is a continuous separation method based…

Fluid Dynamics · Physics 2014-04-15 Timothy J. Bowman , German Drazer , Joelle Frechette

We discuss the problem of counting the maximum number of distinct states that an isolated physical system can pass through in a given period of time---its maximum speed of dynamical evolution. Previous analyses have given bounds in terms of…

Quantum Physics · Physics 2009-10-30 Norman Margolus , Lev B. Levitin

Motivated by a series of experiments that revealed a temperature dependence of the dynamic scaling regime of growing surfaces, we investigate theoretically how a nonequilibrium growth process reacts to a sudden change of system parameters.…

Statistical Mechanics · Physics 2015-05-14 Yen-Liang Chou , Michel Pleimling , R. K. P. Zia

We propose a proof of convergence of an adaptive method used in molecular dynamics to compute free energy profiles. Mathematically, it amounts to studying the long-time behavior of a stochastic process which satisfies a non-linear…

Analysis of PDEs · Mathematics 2007-06-13 Tony Lelievre , Felix Otto , Mathias Rousset , Gabriel Stoltz