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Mathematical modelling has a long history in the context of collective cell migration, with applications throughout development, disease and regenerative medicine. The aim of modelling in this context is to provide a framework in which to…

Quantitative Methods · Quantitative Biology 2025-06-24 Ruth E. Baker , Rebecca M. Crossley , Carles Falco , Simon F. Martina-Perez

We have used the Monte Carlo based computer models to show that selection pressure could affect the distribution of recombination hotspots along the chromosome. Close to critical crossover rate, where genomes may switch between the…

Genomics · Quantitative Biology 2015-05-13 Jakub Kowalski , Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

Sequential techniques can enhance the efficiency of the approximate Bayesian computation algorithm, as in Sisson et al.'s (2007) partial rejection control version. While this method is based upon the theoretical works of Del Moral et al.…

Computation · Statistics 2010-10-11 Mark A. Beaumont , Jean-Marie Cornuet , Jean-Michel Marin , Christian P. Robert

This paper presents a simple model for repeated measurement of a quantum system: the evolution of a free particle, simulated by discretising the particle's position. This model is easily simulated by computer and provides a useful arena to…

Quantum Physics · Physics 2009-11-06 David Wallace

It has recently been suggested that the fundamental haploid-diploid cycle of eukaryotic sex exploits a rudimentary form of the Baldwin effect. Thereafter the other associated phenomena can be explained as evolution tuning the amount and…

Populations and Evolution · Quantitative Biology 2020-03-17 Larry Bull

Monte Carlo simulations on the SK model have been done to investigate aging processes after a rapid quench from $T=\infty$ to the spin-glass phase. The time range of simulations is taken care of so that the system does not surmount…

Disordered Systems and Neural Networks · Physics 2008-02-03 Hajime Takayama , Hajime Yoshino , Koji Hukushima

The aim of this paper is two-fold. First, we propose a new computational method to investigate the particularities of evolution. Second, we apply this method to a model of gene regulatory networks (GRNs) and explore the evolution of…

Molecular Networks · Quantitative Biology 2022-01-21 Tadamune Kaneko , Macoto Kikuchi

Recent studies on the phenomenology of ageing in certain many-particle systems which are at a critical point of their non-equilibrium steady-states, are reviewed. Examples include the contact process, the parity-conserving…

Statistical Mechanics · Physics 2007-05-23 Malte Henkel

Sexual selection theory models evolution of sexual signals and preferences using simple life histories. However, life-history models predict that males benefit from increasing sexual investment approaching old age, producing age-dependent…

Populations and Evolution · Quantitative Biology 2013-12-16 Joel James Adamson

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

We solve a lifecycle model in which the consumer's chronological age does not move in lockstep with calendar time. Instead, biological age increases at a stochastic non-linear rate in time like a broken clock that might occasionally move…

Mathematical Finance · Quantitative Finance 2018-11-27 Huaxiong Huang , Moshe A. Milevsky , Thomas S. Salisbury

A model for artificial evolution in native x86 Windows systems has been developed at the end of 2010. In this text, further improvements and additional analogies to natural microbiologic processes are presented. Several experiments indicate…

Neural and Evolutionary Computing · Computer Science 2011-08-09 Thomas Sperl

We propose a generic model of eco-systems, with a {\it hierarchical} food web structure. In our computer simulations we let the eco-system evolve continuously for so long that that we can monitor extinctions as well as speciations over…

Populations and Evolution · Quantitative Biology 2009-11-10 Debashish Chowdhury , Dietrich Stauffer

The conventional voter model is modified so that an agent's switching rate depends on the `age' of the agent, that is, the time since the agent last switched opinion. In contrast to previous work, age is continuous in the present model. We…

Physics and Society · Physics 2024-08-01 Joseph W. Baron , Antonio F. Peralta , Tobias Galla , Raul Toral

One of the most active areas of physics in the last decades has been that of critical phenomena, and Monte Carlo simulations have played an important role as a guide for the validation and prediction of system properties close to the…

Biological Physics · Physics 2007-05-23 Maria del Pilar Monsivais-Alonso

A new approach to understanding evolution [Val09], namely viewing it through the lens of computation, has already started yielding new insights, e.g., natural selection under sexual reproduction can be interpreted as the Multiplicative…

Populations and Evolution · Quantitative Biology 2016-04-26 Ruta Mehta , Ioannis Panageas , Georgios Piliouras , Prasad Tetali , Vijay V. Vazirani

We propose a class of evolutionary models that involves an arbitrary exchangeable process as the breeding process and different selection schemes. In those models, a new genome is born according to the breeding process, and then a genome is…

Neural and Evolutionary Computing · Computer Science 2020-08-25 Jüri Lember , Chris Watkins

This note presents an Agent-Based Model (ABM) with Monte Carlo sampling, designed to simulate the behaviour of a population of objects over time. The model incorporates damage functions with the risk parameters of the ABC framework to…

Computers and Society · Computer Science 2024-07-02 Josep Grau-Bové , Miriam Andrews

Ignoring the differences between countries, human reproductive and dispersal behaviors can be described by some standardized models, so whether there is a universal law of population growth hidden in the abundant and unstructured data from…

Physics and Society · Physics 2024-02-08 Jiajun Ma , Qinghua Chen , Xiaosong Chen , Jingfang Fan , Xiaomeng Li , Yi Shi

The long-time dynamics of the 1D contact process suddenly brought out of an uncorrelated initial state is studied through a light-cone transfer-matrix renormalisation group approach. At criticality, the system undergoes ageing which is…

Statistical Mechanics · Physics 2007-05-23 Tilman Enss , Malte Henkel , Alan Picone , Ulrich Schollwöck