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In living cells, protein-rich condensates can wet the cell membrane and surfaces of membrane-bound organelles. Interestingly, many phase-separating proteins also bind to membranes leading to a molecular layer of bound molecules. Here we…

Biological Physics · Physics 2022-03-22 Xueping Zhao , Giacomo Bartolucci , Alf Honigmann , Frank Jülicher , Christoph A. Weber

Cell spreading is investigated at various scales in order to understand motility of living cells which is essential for a range of physiological activities in higher organisms as well as in microbes. At a microscopic scale, it has been seen…

Cell Behavior · Quantitative Biology 2009-11-13 A. Bhattacharyay

Labyrinthine patterns arise in two-dimensional physical systems submitted to competing interactions, ranging from the fields of solid-state physics to hydrodynamics. For systems of interacting particles, labyrinthine and stripe phases were…

Soft Condensed Matter · Physics 2015-12-16 Simon Merminod , Timothee Jamin , Eric Falcon , Michael Berhanu

We study the shape dynamics of a two-component fluid membrane, using a dynamical triangulation monte carlo simulation and a Langevin description. Phase separation induces morphology changes depending on the lateral mobility of the lipids.…

Soft Condensed Matter · Physics 2009-10-30 P. B. Sunil Kumar , Madan Rao

We describe a simple coarse-grained model which is suited to study lipid layers and their phase transitions. Lipids are modeled by short semiflexible chains of beads with a solvophilic head and a solvophobic tail component. They are forced…

Biological Physics · Physics 2007-08-06 F. Schmid , D. Duchs , O. Lenz , B. West

A new simple method for the first order phase transition kinetics is suggested. The metastable phase consumption can be imagined in frames of the modisperse approximation for the distribution of the droplets sizes. In all situations of the…

Atmospheric and Oceanic Physics · Physics 2007-05-23 V. Kurasov

In this paper we present the results of a large-scale numerical investigation of structural properties of a model of cell membrane, simulated as a bilayer of flexible molecules in vacuum. The study was performed by carrying out extensive…

Biological Physics · Physics 2009-11-07 G. La Penna , S. Letardi , V. Minicozzi , S. Morante , G. C. Rossi , G. Salina

We study the diffusion of a linear polymer in the presence of permeable membranes without excluded volume interactions, using scaling theory and Monte Carlo simulations. We find that the average time it takes for a chain with polymerization…

Condensed Matter · Physics 2016-08-31 Hyoungsoo Yoon , J. M. Deutsch

Proteins and nucleic acids can spontaneously self-assemble into membraneless droplet-like compartments, both in vitro and in vivo. A key component of these droplets are multi-valent proteins that possess several adhesive domains with…

Biomolecules · Quantitative Biology 2020-01-10 Srivastav Ranganathan , Eugene Shakhnovich

We investigate the properties of membranes under tension by Monte-Carlo simulations of a generic coarse-grained model for lipid bilayers. We give a comprising overview of the behavior of several membrane characteristics, such as the area…

Biological Physics · Physics 2010-03-17 Jörg Neder , Beate West , Peter Nielaba , Friederike Schmid

We investigate the aging behavior of lattice-gas models with constrained dynamics in which particle exchange with a reservoir is allowed. Such models provide a particularly simple interpretation of aging phenomena as a slow approach to…

Statistical Mechanics · Physics 2009-10-30 Jorge Kurchan , Luca Peliti , Mauro Sellitto

We introduce a meshfree collocation framework to model the phase change from liquid to vapor at or above the boiling point. While typical vaporization or boiling simulations focus on the vaporization from the bulk of the fluid, here we…

Fluid Dynamics · Physics 2023-03-22 Pratik Suchde , Heinrich Kraus , Benjamin Bock-Marbach , Joerg Kuhnert

A crystal lattice, when confined to the surface of a cylinder, must have a periodic structure that is commensurate with the cylinder circumference. This constraint can frustrate the system, leading to oblique crystal lattices or to…

Soft Condensed Matter · Physics 2013-07-03 D. A. Wood , C. D. Santangelo , A. D. Dinsmore

This paper presents a phase-field model for simulating the three-dimensional deformation of vesicle membranes, incorporating area-difference elasticity, with constraints on bulk volume and surface area. We develop efficient numerical…

Numerical Analysis · Mathematics 2025-11-19 Yihong Liang , Emine Celiker , Ping Lin

Native membranes of biological cells display melting transitions of their lipids at a temperature of 10-20 degrees below body temperature. Such transitions can be observed in various bacterial cells, in nerves, in cancer cells, but also in…

Biological Physics · Physics 2020-08-10 Thomas Heimburg

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

We study the evolution from a liquid to a crystal phase in two-dimensional curved space. At early times, while crystal seeds grow preferentially in regions of low curvature, the lattice frustration produced in regions with high curvature is…

Soft Condensed Matter · Physics 2015-06-16 Nicolas A. Garcia , Richard A. Register , Daniel A. Vega , Leopoldo R. Gomez

We performed dynamic simulations of spheres with short-range attractive interactions for many values of interaction strength and range. Fast crystallization occurs in a localized region of this parameter space, but the character of…

Soft Condensed Matter · Physics 2015-07-27 Thomas K. Haxton , Lester O. Hedges , Stephen Whitelam

The conformation and the phase diagram of a membrane protein are investigated via grand canonical ensemble approach using a homopolymer model. We discuss the nature and pathway of $\alpha$-helix integration into the membrane that results…

Soft Condensed Matter · Physics 2009-10-31 Pyeong Jun Park , W. Sung

We present a brief analysis of the crossover phase diagram for the decay of a metastable phase in a simple dynamic lattice-gas model of a two-phase system. We illustrate the nucleation-theoretical analysis with dynamic Monte Carlo…

Materials Science · Physics 2009-10-31 M. A. Novotny , P. A. Rikvold , M. Kolesik , D. M. Townsley , R. A. Ramos