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We analyse a continuous-time random walk model with stochastic reversals of direction. There is no external potential but the reorientation mechanism generates a non-zero current from asymmetry in the forward and backward waiting-time…

Statistical Mechanics · Physics 2026-02-27 Venkata D. Pamulaparthy , Rosemary J. Harris

Einstein's explanation of Brownian motion provided one of the cornerstones which underlie the modern approaches to stochastic processes. His approach is based on a random walk picture and is valid for Markovian processes lacking long-term…

Statistical Mechanics · Physics 2009-11-10 I. M. Sokolov , J. Klafter

A variational formula for the asymptotic variance of general Markov processes is obtained. As application, we get a upper bound of the mean exit time of reversible Markov processes, and some comparison theorems between the reversible and…

Probability · Mathematics 2021-06-02 Lu-Jing Huang , Yong-Hua Mao , Tao Wang

We analyze the statistical properties of a temporal point process driven by a confined fractional Brownian motion. The event count distribution and power spectral density of this non--Markovian point process exhibit power--law scaling. We…

Statistical Mechanics · Physics 2022-08-31 Aleksejus Kononovicius , Rytis Kazakevičius , Bronislovas Kaulakys

Stochastic point processes with refractoriness appear frequently in the quantitative analysis of physical and biological systems, such as the generation of action potentials by nerve cells, the release and reuptake of vesicles at a synapse,…

Probability · Mathematics 2015-07-28 Moritz Deger , Moritz Helias , Stefano Cardanobile , Fatihcan M. Atay , Stefan Rotter

Recent experiments using fluorescence spectroscopy have been able to probe the dynamics of conformational fluctuations in proteins. The fluctuations are Gaussian but do not decay exponentially, and are therefore, non-Markovian. We present a…

Statistical Mechanics · Physics 2008-10-14 Arti Dua , R. Adhikari

We consider a walker moving in a one-dimensional interval with absorbing boundaries under the effect of Markovian resettings to the initial position. The walker's motion follows a random walk characterized by a general waiting time…

Statistical Mechanics · Physics 2022-05-25 Vicenç Méndez , Axel Masó-Puigdellosas , Daniel Campos

In this paper, we develop an encounter-based model of partial surface adsorption for fractional diffusion in a bounded domain. We take the probability of adsorption to depend on the amount of particle-surface contact time, as specified by a…

Statistical Mechanics · Physics 2023-03-21 Paul C Bressloff

We consider the first exit time of a nonnegative Harris-recurrent Markov process from the interval $[0,A]$ as $A\to\infty$. We provide an alternative method of proof of asymptotic exponentiality of the first exit time (suitably…

Probability · Mathematics 2010-06-07 Moshe Pollak , Alexander G. Tartakovsky

In spatially distributed cellular systems, it is often convenient to represent complicated auxiliary pathways and spatial transport by time-delayed reaction rates. Furthermore, many of the reactants appear in low numbers necessitating a…

Quantitative Methods · Quantitative Biology 2015-05-14 Matthew Scott

Rapid rebinding of molecular interaction partners that are in close proximity after dissociation leads to a dissociation and association kinetics that can profoundly differ from predictions based on bulk reaction models. The cause of this…

Quantitative Methods · Quantitative Biology 2015-04-30 Thorsten Prüstel , Martin Meier-Schellersheim

We study the fluctuations of time-additive random observables in the stochastic dynamics of a system of $N$ non-interacting Ising spins. We mainly consider the case of all-to-all dynamics where transitions are possible between any two spin…

Statistical Mechanics · Physics 2022-12-28 Juan P. Garrahan , Chokri Manai , Simone Warzel

Exploiting previous results on Markovian dynamics and fluctuation theorems, we study the consequences of memory effects on single realizations of nonequilibrium processes within an open system approach. The entropy production along single…

Statistical Mechanics · Physics 2015-06-12 Bruno Leggio , Anna Napoli , Heinz-Peter Breuer , Antonino Messina

Local diffusivity of a protein depends crucially on the conformation, and the conformational fluctuations are often non-Markovian. Here, we investigate the Langevin equation with non-Markovian fluctuating diffusivity, where the fluctuating…

Statistical Mechanics · Physics 2023-04-26 Mutsumi Kimura , Takuma Akimoto

We model the dynamics of the leaky integrate-fire neuron under periodic stimulation as a Markov process with respect to the stimulus phase. This avoids the unrealistic assumption of a stimulus reset after each spike made in earlier work and…

Biological Physics · Physics 2009-10-31 Hans E. Plesser , Theo Geisel

We study the large deviations of additive quantities, such as energy or current, in stochastic processes with intermittent reset. Via a mapping from a discrete-time reset process to the Poland-Scheraga model for DNA denaturation, we derive…

Statistical Mechanics · Physics 2017-02-09 Rosemary J. Harris , Hugo Touchette

For a class of excitatory spiking neuron models with delayed feedback fed with a Poisson stochastic process, it is proven that the stream of output interspike intervals cannot be presented as a Markov process of any order. Keywords: spiking…

Neurons and Cognition · Quantitative Biology 2015-08-19 Alexander K. Vidybida

We propose stochastic, non-parametric activation functions that are fully learnable and individual to each neuron. Complexity and the risk of overfitting are controlled by placing a Gaussian process prior over these functions. The result is…

Machine Learning · Statistics 2017-12-01 Sebastian Urban , Marcus Basalla , Patrick van der Smagt

The study of diffusion with preferential returns to places visited in the past has attracted an increased attention in recent years. In these highly non-Markov processes, a standard diffusive particle intermittently resets at a given rate…

Statistical Mechanics · Physics 2024-05-08 Denis Boyer , Satya N. Majumdar

The aim of this paper is to investigate how the correlation properties of a stationary Markovian stochastic processes affect the First Passage Time distribution. First Passage Time issues are a classical topic in stochastic processes…

Statistical Mechanics · Physics 2014-03-31 S. Micciché