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We have performed parallel tempering Monte Carlo simulations using a simple continuum heteropolymer model for proteins. All ten heteropolymer sequences which we have studied have shown first-order transitions at low temperature to ordered…

Soft Condensed Matter · Physics 2010-01-05 J. E. Magee , J. Warwicker , L. Lue

We use a three dimensional cubic lattice model of proteins to study their properties that determine folding to the native state. The protein chain is modeled as a sequence of $N$ beads. The interactions between beads are taken from a…

Condensed Matter · Physics 2007-05-23 D. K. Klimov , D. Thirumalai

The correlation between a random sequence and its transformed sequences is studied. In the case of a permutation operation or, in other word, the shuffling operation, it is shown that the correlation can be so small that the sequences can…

High Energy Physics - Lattice · Physics 2015-06-25 Nobuyasu Ito , Macoto Kikuchi , Yutaka Okabe

Natural proteins fold to a unique, thermodynamically dominant state. Modeling of the folding process and prediction of the native fold of proteins are two major unsolved problems in biophysics. Here, we show successful all-atom ab initio…

Biomolecules · Quantitative Biology 2007-05-23 Jae Shick Yang , William W. Chen , Jeffrey Skolnick , Eugene I. Shakhnovich

We have observed the spontaneous appearance of currents in a ring of ultracold fermionic atoms (6Li) with attractive interactions, following a quench to a BCS-like pair superfluid. We have measured the winding number probability…

Quantum Gases · Physics 2024-06-03 Daniel G. Allman , Parth Sabharwal , Kevin C. Wright

We study folding in 16-monomer heteropolymers on the square lattice. For a given sequence, thermodynamic properties and stability of the native state are unique. However, the kinetics of folding depends on the model of dynamics adopted for…

Statistical Mechanics · Physics 2009-10-31 Trinh Xuan Hoang , Marek Cieplak

We propose the use of recurrent neural networks for classifying phases of matter based on the dynamics of experimentally accessible observables. We demonstrate this approach by training recurrent networks on the magnetization traces of two…

Disordered Systems and Neural Networks · Physics 2018-08-22 Evert van Nieuwenburg , Eyal Bairey , Gil Refael

We use a bath of chaotic surface waves in water to mechanically and macroscopically mimic the thermal behavior of a short articulated chain with only nearest-neighbor interactions. The chaotic waves provide isotropic and random agitation to…

Soft Condensed Matter · Physics 2015-03-05 Kyle J. Welch , Clayton S. G. Kilmer , Eric I. Corwin

Stochastic chains represent a wide and key variety of phenomena in many branches of science within the context of Information Theory and Thermodynamics. They are typically approached by a sequence of independent events or by a memoryless…

Statistical Mechanics · Physics 2017-03-06 J. Ricardo Arias-Gonzalez

The thermodynamic behavior of a three-dimensional off-lattice model for protein folding is probed. The model has only two types of residues, hydrophobic and hydrophilic. In absence of local interactions, native structure formation does not…

Chemical Physics · Physics 2009-10-30 Anders Irbäck , Carsten Peterson , Frank Potthast , Ola Sommelius

The thermodynamics of a long self-repulsive chain is studied. In $D<4$ dimensions it shows two distinctly different regimes, corresponding to weak and strong correlations in the system. A simple microscopic analytical model is presented…

Statistical Mechanics · Physics 2007-05-23 A. N. Rubtsov

We study the behaviour of interacting self-propelled particles, whose self-propulsion speed decreases with their local density. By combining direct simulations of the microscopic model with an analysis of the hydrodynamic equations obtained…

Statistical Mechanics · Physics 2012-06-25 F. D. C. Farrell , J. Tailleur , D. Marenduzzo , M. C. Marchetti

The ability to understand and eventually predict the emergence of information and activation cascades in social networks is core to complex socio-technical systems research. However, the complexity of social interactions makes this a…

Physics and Society · Physics 2015-06-16 Pablo Piedrahíta , Javier Borge-Holthoefer , Yamir Moreno , Alex Arenas

We study numerically the phase-ordering kinetics following a temperature quench of the Ising model with single spin flip dynamics on a class of graphs, including geometrical fractals and random fractals, such as the percolation cluster. For…

Statistical Mechanics · Physics 2010-12-20 R. Burioni , D. Cassi , F. Corberi , A. Vezzani

Using Monte Carlo dynamics and the Monte Carlo Histogram Method, the simple three-dimensional 27 monomer lattice copolymer is examined in depth. The thermodynamic properties of various sequences are examined contrasting the behavior of good…

chem-ph · Physics 2009-10-28 Nicholas D. Socci , José Nelson Onuchic

Stochastic processes can model many emerging phenomena on networks, like the spread of computer viruses, rumors, or infectious diseases. Understanding the dynamics of such stochastic spreading processes is therefore of fundamental interest.…

Social and Information Networks · Computer Science 2019-01-07 Gerrit Großmann , Verena Wolf

Model chains are studied via Monte Carlo simulations which are deposited with a fixed flux on a substrate. They may represent, e.g., stiff lipophilic chains with an head group and tail groups mimicking the alkyl chain. After some subsequent…

Materials Science · Physics 2015-06-15 Pritam Kumar Jana , Andreas Heuer

The random walk process underlies the description of a large number of real world phenomena. Here we provide the study of random walk processes in time varying networks in the regime of time-scale mixing; i.e. when the network connectivity…

Background: Designing amino acid sequences that are stable in a given target structure amounts to maximizing a conditional probability. A straightforward approach to accomplish this is a nested Monte Carlo where the conformation space is…

Soft Condensed Matter · Physics 2016-08-31 Anders Irbäck , Carsten Peterson , Frank Potthast , Erik Sandelin

The process of protein folding from an unfolded state to a biologically active, folded conformation is governed by many parameters e.g the sequence of amino acids, intermolecular interactions, the solvent, temperature and chaperon…

Soft Condensed Matter · Physics 2010-10-19 Pragya Shukla