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Retrosynthesis, the process of breaking down a target molecule into simpler precursors through a series of valid reactions, stands at the core of organic chemistry and drug development. Although recent machine learning (ML) research has…

Artificial Intelligence · Computer Science 2026-05-12 Haorui Wang , Jeff Guo , Lingkai Kong , Rampi Ramprasad , Philippe Schwaller , Yuanqi Du , Chao Zhang

We examine the effect of accuracy of high-order spectral element methods, with or without adaptive mesh refinement (AMR), in the context of a classical configuration of magnetic reconnection in two space dimensions, the so-called…

Fluid Dynamics · Physics 2009-11-13 D. Rosenberg , A. Pouquet , P. D. Mininni

A classic approach for solving differential equations with neural networks builds upon neural forms, which employ the differential equation with a discretisation of the solution domain. Making use of neural forms for time-dependent…

Neural and Evolutionary Computing · Computer Science 2022-09-02 Toni Schneidereit , Michael Breuß

Retrieval-Augmented Generation (RAG) improves factual grounding by incorporating external knowledge into language model generation. However, when retrieved context is noisy, unreliable, or inconsistent with the model's parametric knowledge,…

Computation and Language · Computer Science 2026-04-06 Jaemin Kim , Jong Chul Ye

To backpropagate the gradients through stochastic binary layers, we propose the augment-REINFORCE-merge (ARM) estimator that is unbiased, exhibits low variance, and has low computational complexity. Exploiting variable augmentation,…

Machine Learning · Statistics 2019-09-11 Mingzhang Yin , Mingyuan Zhou

Adaptive randomized pivoting (ARP) is a recently proposed and highly effective algorithm for column subset selection. This paper reinterprets the ARP algorithm by drawing connections to the volume sampling distribution and active learning…

Machine Learning · Statistics 2026-04-06 Ethan N. Epperly

Convolutional neural networks can automatically learn features via deep network architectures and given input samples. However, the robustness of obtained models may face challenges in varying scenes. Bigger differences in network…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Ziang Wu , Jinwei Xie , Xuanyu Zhang , Tao Wang , Yongjun Zhang , Qi Zhu , Chunwei Tian

In ultrasound (US) imaging, various types of adaptive beamforming techniques have been investigated to improve the resolution and contrast-to-noise ratio of the delay and sum (DAS) beamformers. Unfortunately, the performance of these…

Image and Video Processing · Electrical Eng. & Systems 2020-02-25 Shujaat Khan , Jaeyoung Huh , Jong Chul Ye

We present a dual-resolution molecular dynamics (MD) simulation of liquid water employing a recently introduced Adaptive Resolution Scheme (AdResS). The spatially adaptive molecular resolution procedure allows for changing from a…

Soft Condensed Matter · Physics 2011-11-10 Silvina Matysiak , Cecilia Clementi , Matej Praprotnik , Kurt Kremer , Luigi Delle Site

We implement general relativistic hydrodynamics in the moving-mesh code AREPO. We also couple a solver for the Einstein field equations employing the conformal flatness approximation. The implementation is validated by evolving isolated…

High Energy Astrophysical Phenomena · Physics 2024-01-10 Georgios Lioutas , Andreas Bauswein , Theodoros Soultanis , Rüdiger Pakmor , Volker Springel , Friedrich K. Röpke

In this fluid dynamics video, results from high fidelity numerical simulations are presented, which have been carried out to study the flow and droplet dynamics of liquid sheets formed by two impinging jets. A three-dimensional…

Fluid Dynamics · Physics 2011-10-18 Xiaodong Chen , Prashant Khare , Dongjun Ma , Vigor Yang

Reaction feasibility prediction, as a fundamental problem in computational chemistry, has benefited from diverse tools enabled by recent advances in artificial intelligence, particularly large language models. However, the performance of…

Artificial Intelligence · Computer Science 2026-05-11 Ye Liu , Botao Yu , Xinyi Ling , Daniel Adu-Ampratwum , Xia Ning

We construct, analyse and assess various schemes of second order of accuracy in space and time for model advection-diffusion-reaction differential equations. The constructed schemes are meant to be of practical use in solving industrial…

Numerical Analysis · Mathematics 2023-01-25 Saray Busto , Eleuterio F. Toro , Maria Elena Vazquez-Cendon

We present a new algorithm to solve the equations of radiation hydrodynamics (RHD) in a frequency-integrated, two-moment formulation. Novel features of the algorithm include i) the adoption of a non-local Variable Eddington Tensor (VET)…

Instrumentation and Methods for Astrophysics · Physics 2023-01-25 Shyam H. Menon , Christoph Federrath , Mark R. Krumholz , Rolf Kuiper , Benjamin D. Wibking , Manuel Jung

Molecular Dynamics (MD) simulations are fundamental computational tools for the study of proteins and their free energy landscapes. However, sampling protein conformational changes through MD simulations is challenging due to the relatively…

Biomolecules · Quantitative Biology 2023-07-20 Diego E. Kleiman , Hassan Nadeem , Diwakar Shukla

We present a class of high order finite volume schemes for the solution of non-conservative hyperbolic systems that combines the one-step ADER-WENO finite volume approach with space-time adaptive mesh refinement (AMR). The resulting…

Numerical Analysis · Mathematics 2015-06-15 Michael Dumbser , Arturo Hidalgo , Olindo Zanotti

An iterative method is derived for image reconstruction. Among other attributes, this method allows constraints unrelated to the radiation measurements to be incorporated into the reconstructed image. A comparison is made with the widely…

Computational Physics · Physics 2011-01-06 Clinton DeW. Van Siclen

Machine learning offers a powerful framework for validating and predicting atomic mass. We compare three improved neural network methods for representation and extrapolation for atomic mass prediction. The powerful method, adopting a…

Nuclear Theory · Physics 2025-03-18 Yiming Huang , Jinhui Chen , Jiangyong Jia , Lu-Meng Liu , Yu-Gang Ma , Chunjian Zhang

Retrieval-Augmented Generation (RAG) systems leverage Large Language Models (LLMs) to generate accurate and reliable responses that are grounded in retrieved context. However, LLMs often generate inconsistent outputs for semantically…

Computation and Language · Computer Science 2025-10-17 Xujun Peng , Anoop Kumar , Jingyu Wu , Parker Glenn , Daben Liu

We summarize recent efforts to develop an angular-momentum-conserving variant of the Density Matrix Renormalization Group method into a practical truncation strategy for large-scale shell model calculations of atomic nuclei. Following a…

Nuclear Theory · Physics 2011-05-12 S. Pittel , B. Thakur , N. Sandulescu
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