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Related papers: Prebiotic Homochirality as a Critical Phenomenon

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The emergence and spreading of chirality on the early Earth is considered by studying a set of reaction-diffusion equations based on a polymerization model. It is found that effective mixing of the early oceans is necessary to reach the…

Biomolecules · Quantitative Biology 2015-06-26 Tuomas Multamaki , Axel Brandenburg

The role of asymmetry on the evolution of prebiotic homochirality is investigated in the context of autocatalytic polymerization reaction networks. A model featuring enantiometric cross-inhibition and chiral bias is used to study the…

Astrophysics · Physics 2009-11-11 Marcelo Gleiser

A key open question in the study of life is the origin of biomolecular homochirality: almost every life-form on Earth has exclusively levorotary amino acids and dextrorotary sugars. Will the same handedness be preferred if life is found…

Biomolecules · Quantitative Biology 2015-06-04 Marcelo Gleiser , Sara Imari Walker

We investigate the possibility that prebiotic homochirality can be achieved exclusively through chiral-selective reaction rate parameters without any other explicit mechanism for chiral bias. Specifically, we examine an open network of…

Biomolecules · Quantitative Biology 2015-06-03 Marcelo Gleiser , Bradley J. Nelson , Sara Imari Walker

The question of the onset of the homochirality on prebiotic Earth still remains a fundamental question in the quest for the origin of life. Recent works in this field introduce the concept of recycling, rather than the traditional open-flow…

Molecular Networks · Quantitative Biology 2011-05-23 Raphael Plasson

The search for life elsewhere in the universe is a pivotal question in modern science. However, to address whether life is common in the universe we must first understand the likelihood of abiogenesis by studying the origin of life on…

Astrophysics · Physics 2008-11-11 Marcelo Gleiser , Sara Imari Walker

The selection of a single molecular handedness, or homochirality across all living matter, is a mystery in the origin of life. Frank's seminal model showed in the fifties how chiral symmetry breaking can occur in non-equilibrium chemical…

Statistical Mechanics · Physics 2021-01-25 Gabin Laurent , David Lacoste , Pierre Gaspard

Many of the building blocks of life such as amino acids and nucleotides are chiral, i.e., different from their mirror image. Contemporary life selects and synthesizes only one of two possible handednesses. In an abiotic environment,…

Biomolecules · Quantitative Biology 2022-09-20 Axel Brandenburg

Most biomolecules occur in mirror, or chiral, images of each other. However, life is homochiral: proteins contain almost exclusively levorotatory (L) amino acids, while only dextrorotatory (R) sugars appear in RNA and DNA. The mechanism…

Astrophysics · Physics 2009-06-23 Marcelo Gleiser , Joel Thorarinson , Sara Imari Walker

A generalized autocatalytic model for chiral polymerization is investigated in detail. Apart from enantiomeric cross-inhibition, the model allows for the autogenic (non-catalytic) formation of left and right-handed monomers from a substrate…

Biomolecules · Quantitative Biology 2008-07-24 Marcelo Gleiser , Sara Imari Walker

A recently proposed model of non-autocatalytic reactions in dipeptide reactions leading to spontaneous symmetry breaking and homochirality is examined. The model is governed by activation, polymerization, epimerization and depolymerization…

Biomolecules · Quantitative Biology 2007-11-01 Axel Brandenburg , Harry J. Lehto , Kirsi M. Lehto

Biological systems are homochiral, raising the question of how a racemic mixture of prebiotically synthesized biomolecules could attain a homochiral state at the network level. Based on our recent results, we aim to address a related…

Biological Physics · Physics 2025-04-15 S. Furkan Ozturk , Dimitar D. Sasselov , John D. Sutherland

Conceptualizing planetary habitability depends on understanding how living organisms originated and what features of environments are essential to foster abiogenesis. Estimates of the abundance of life's building blocks are confounded by…

Earth and Planetary Astrophysics · Physics 2018-07-12 Daniel S. Helman

Living systems have evolved to efficiently consume available energy sources using an elaborate circuitry of chemical reactions which, puzzlingly, bear a strict restriction to asymmetric chiral configurations. While autocatalysis is known to…

Chemical Physics · Physics 2022-05-25 William D. Piñeros , Tsvi Tlusty

Homochirality, i.e. the dominance across all living matter of one enantiomer over the other among chiral molecules, is thought to be a key step in the emergence of life. Building on ideas put forward by Frank and many others, we proposed…

Statistical Mechanics · Physics 2022-02-23 Gabin Laurent , David Lacoste , Pierre Gaspard

The emergence of biomolecular homochirality is a critically important question about life phenomenon and the origins of life. In a previous paper (arXiv:1309.1229), I tentatively put forward a new hypothesis that the emergence of a single…

Biological Physics · Physics 2015-04-06 Wei Wang

The emergence of biomolecular homochirality is a critical open question in the field of origins of life. In order to seek out an answer to this unsettled issue, a number of mechanisms have been offered over time, but it still remains a…

Biological Physics · Physics 2020-01-13 Wei Wang

Any search for present or past life beyond Earth should consider the initial processes and related environmental controls that might have led to its start. As on Earth, such an understanding lies well beyond how simple organic molecules…

Instrumentation and Methods for Astrophysics · Physics 2020-08-12 Timothy W. Lyons , Karyn Rogers , Ramanarayanan Krishnamurthy , Loren Williams , Simone Marchi , Edward Schwieterman , Noah Planavsky , Christopher Reinhard

We study evolutionary processes induced by spatio-temporal dynamics in prebiotic evolution. Using numerical simulations we demonstrate that hypercycles emerge from complex interaction structures in multispecies systems. In this work we also…

Populations and Evolution · Quantitative Biology 2007-05-23 Pan-Jun Kim , Hawoong Jeong

Chirality is a feature of many biological systems and much research has been focused on understanding the origin and implications of this property. Famously, sugars and amino acids found in nature are homochiral, i.e., chiral symmetry is…

Cell Behavior · Quantitative Biology 2023-07-28 Ludwig A. Hoffmann , Luca Giomi
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