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Background: Many mathematical models have now been employed across every area of systems biology. These models increasingly involve large numbers of unknown parameters, have complex structure which can result in substantial evaluation time…

Molecular Networks · Quantitative Biology 2018-01-15 Ian Vernon , Junli Liu , Michael Goldstein , James Rowe , Jen Topping , Keith Lindsey

In the problem of selecting variables in a multivariate linear regression model, we derive new Bayesian information criteria based on a prior mixing a smooth distribution and a delta distribution. Each of them can be interpreted as a fusion…

Statistics Theory · Mathematics 2022-09-29 Haruki Kono , Tatsuya Kubokawa

Theories can be represented as statistical models for empirical testing. There is a vast literature on model selection and multimodel inference that focuses on how to assess which statistical model, and therefore which theory, best fits the…

Applications · Statistics 2021-10-06 Carl Falk , Michael Muthukrishna

When combining data sets to perform parameter inference, the results will be unreliable if there are unknown systematics in data or models. Here we introduce a flexible methodology, BACCUS: BAyesian Conservative Constraints and Unknown…

Cosmology and Nongalactic Astrophysics · Physics 2018-07-04 José Luis Bernal , John A. Peacock

The estimation of unknown values of parameters (or hidden variables, control variables) that characterise a physical system often relies on the comparison of measured data with synthetic data produced by some numerical simulator of the…

Machine Learning · Computer Science 2019-01-28 Xi Chen , Mike Hobson

We apply two Bayesian hierarchical inference schemes to infer shear power spectra, shear maps and cosmological parameters from the CFHTLenS weak lensing survey - the first application of this method to data. In the first approach, we sample…

Cosmology and Nongalactic Astrophysics · Physics 2017-05-10 Justin Alsing , Alan F. Heavens , Andrew H. Jaffe

We present a Bayesian analysis of large-scale structure and cosmic microwave background data to constrain the form of the primordial power spectrum. We have extended the usual presumption of a scale invariant spectrum to include: (i) a…

Astrophysics · Physics 2009-11-11 M. Bridges , A. N. Lasenby , M. P. Hobson

Bayesian (Probabilistic) Machine Learning is used to probe the opacity of the Universe. It relies on a generative process where the model is the key object to generate the data involving the unknown parameters of the model, our prior…

Cosmology and Nongalactic Astrophysics · Physics 2020-08-17 Emilio Elizalde , Martiros Khurshudyan

This is an introduction to Bayesian inference with a focus on hierarchical models and hyper-parameters. We write primarily for an audience of Bayesian novices, but we hope to provide useful insights for seasoned veterans as well. Examples…

Instrumentation and Methods for Astrophysics · Physics 2025-05-26 Eric Thrane , Colm Talbot

Consider the setting where there are B>1 candidate statistical models, and one is interested in model selection. Two common approaches to solve this problem are to select a single model or to combine the candidate models through model…

Methodology · Statistics 2021-04-22 Qingying Zong , Jonathan R. Bradley

We provide a flexible framework for selecting among a class of additive partial linear models that allows both linear and nonlinear additive components. In practice, it is challenging to determine which additive components should be…

Methodology · Statistics 2021-09-20 Seonghyun Jeong , Taeyoung Park , David A. van Dyk

This paper presents an efficient Bayesian framework for solving nonlinear, high-dimensional model calibration problems. It is based on a Variational Bayesian formulation that aims at approximating the exact posterior by means of solving an…

Applications · Statistics 2015-11-02 Isabell M. Franck , P. S. Koutsourelakis

The choice of tuning parameters in Bayesian variable selection is a critical problem in modern statistics. In particular, for Bayesian linear regression with non-local priors, the scale parameter in the non-local prior density is an…

Statistics Theory · Mathematics 2019-02-25 Xuan Cao , Kshitij Khare , Malay Ghosh

The next generation of weak lensing probes can place strong constraints on cosmological parameters by measuring the mass distribution and geometry of the low redshift universe. We show that a future all-sky tomographic cosmic shear survey…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-17 Ivan Debono

What do the data, as distinguished from cosmological models, tell us about cosmological parameters that determined the model of the universe? In this paper, we address this question in the context of the WMAP angular power spectra for the…

Cosmology and Nongalactic Astrophysics · Physics 2012-12-27 Amir Aghamousa , Mihir Arjunwadkar , Tarun Souradeep

Approximate Bayesian computation (ABC) have become a essential tool for the analysis of complex stochastic models. Earlier, Grelaud et al. (2009) advocated the use of ABC for Bayesian model choice in the specific case of Gibbs random…

Methodology · Statistics 2015-03-19 Christian P. Robert , Jean-Marie Cornuet , Jean-Michel Marin , Natesh Pillai

We present a novel approach to derive constraints on neutrino masses from cosmological data, while taking into account our ignorance of the neutrino mass ordering. We derive constraints from a combination of current and future cosmological…

Cosmology and Nongalactic Astrophysics · Physics 2018-02-02 Martina Gerbino , Massimiliano Lattanzi , Olga Mena , Katherine Freese

Learning of a smooth but nonparametric probability density can be regularized using methods of Quantum Field Theory. We implement a field theoretic prior numerically, test its efficacy, and show that the data and the phase space factors…

Condensed Matter · Physics 2007-05-23 Ilya Nemenman , William Bialek

In many hypothesis testing applications, we have mixed priors, with well-motivated informative priors for some parameters but not for others. The Bayesian methodology uses the Bayes factor and is helpful for the informative priors, as it…

Data Analysis, Statistics and Probability · Physics 2022-10-05 Jakob Robnik , Uroš Seljak

Modern imaging techniques heavily rely on Bayesian statistical models to address difficult image reconstruction and restoration tasks. This paper addresses the objective evaluation of such models in settings where ground truth is…

Image and Video Processing · Electrical Eng. & Systems 2026-05-29 Tom Sprunck , Marcelo Pereyra , Tobias Liaudat