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The origin of life is shrouded in mystery, with few surviving clues, obscured by evolutionary competition. Previous reviews have touched on the complementary approaches of top-down and bottom-up synthetic biology to augment our…
Is life a common outcome of physical and chemical processes in the universe? Within our own solar system, a successful search for even primitive life, were it to have an origin independent from life on Earth, would dramatically advance a…
Planetary effects have been attributed to biological processes without scientific rigor. Some generic invisible slow matter from the dark Universe in the form of streams or clusters with occasional large flux enhancements due to planetary…
The Habitable Worlds Observatory (HWO) aims to telescopically constrain the frequency and abundance of biospheres in the solar neighborhood. Origin-of-life theories vary in their predictions for the environmental requirements and the…
The study of origins of life on Earth and the search for life on other planets are closely linked. Prebiotic chemical scenarios can help prioritize planets as targets for the search for life as we know it and can provide informative priors…
'Most habitable worlds in the cosmos will have no remotely detectable signs of life' is proposed as a biological hypothesis to be tested in studies of exoplanets. Habitable planets could be discovered elsewhere in the Universe, yet there…
In the modern search for life elsewhere in the Universe, we are broadly looking for the following: the planets similar to Earth - physical indicators of habitability, and the manifestation of life - the biological signatures. A biosignature…
Gillevinia straata, the scientific name [1, 2] recognizing the first extraterrestrial living form ever nomenclated, as well as the existence of a new biological kingdom, Jakobia, in a new biosphere -Marciana- of what now has become the…
Recent discoveries imply that Early Mars was habitable for life-as-we-know-it; that Enceladus might be habitable; and that many stars have Earth-sized exoplanets whose insolation favors surface liquid water. These exciting discoveries make…
Bayesian Inference is a powerful approach to data analysis that is based almost entirely on probability theory. In this approach, probabilities model {\it uncertainty} rather than randomness or variability. This thesis is composed of a…
A recent study reported that there is evidence life may have originated prior to the formation of the Earth. That conclusion was based on a regression analysis of a certain data set involving evolution of functional genome size across major…
Hypothetical existence of other universes gives an opportunity not only to extend the scope of physics, but the scope of biology, SETI, and METI as well. Some steps of the development of alien life concept shall be briefly summarized, then…
In a multiverse context, determining the probability of being in our particular universe depends on estimating its overall habitability compared to other universes with different values of the fundamental constants. One of the most…
Earth is unusual in bearing life, and in having a large moon. A number of authors have suggested a possible connection between the two, e.g. through lunar stabilisation of the earth's obliquity, or through the effects of the oceanic tides.…
In this paper we review and extend our earlier recent work on thermostated systems. A description of nano-biological systems by Markov chains in coordinate space in the strongly overdamped limit is presented. Characterization of the most…
The existence of life is one of the most fundamental problems of astrophysics. The intriguing existence of progressively complex and apparently improbable living beings should be a general tendency of life in the Universe. We are looking…
The concept of a random Lagrangian is proposed. It is considered as a basis for a new view of the old problems such as renormalization, nonzero vacuum energy and the anthropic principle. It gives rise to nontrivial consequences both in…
High-energy astrophysical events that cause galaxy-scale extinctions have been proposed as a way to explain or mollify the Fermi Paradox, by making the universe at earlier times more dangerous for evolving life, and reducing its present-day…
Abiotic emergence of ordered information stored in the form of RNA is an important unresolved problem concerning the origin of life. A polymer longer than 40--100 nucleotides is necessary to expect a self-replicating activity, but the…
For more than 100 years, humanity (both specialists and enthusiastic laics) has been searching for extraterrestrial life hoping we are not alone. The first step in the quest for extraterrestrial life is to define what and where exactly to…