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We study a general setting of neutral evolution in which the population is of finite, constant size and can have spatial structure. Mutation leads to different genetic types ("traits"), which can be discrete or continuous. Under minimal…

Populations and Evolution · Quantitative Biology 2018-11-02 Alex McAvoy , Ben Adlam , Benjamin Allen , Martin A. Nowak

Phenotypic fluctuations and plasticity can generally affect the course of evolution, a process known as the Baldwin effect. Several studies have recast this effect and claimed that phenotypic plasticity acceler- ates evolutionary rate (the…

Populations and Evolution · Quantitative Biology 2013-05-30 Nen Saito , Shuji Ishihara , Kunihiko Kaneko

Essential to each other, growth and exploration are jointly observed in populations, be it alive such as animals and cells or inanimate such as goods and money. But their ability to move, crucial to cope with uncertainty and optimize…

Statistical Mechanics · Physics 2020-10-06 Thomas Gueudré , David Martin

Motivated by recent understandings in the stochastic natures of gene expression, biochemical signaling, and spontaneous reversible epigenetic switchings, we study a simple deterministic cell population dynamics in which subpopulations grow…

Populations and Evolution · Quantitative Biology 2014-08-04 Hong Qian

A new approach to understanding evolution [Val09], namely viewing it through the lens of computation, has already started yielding new insights, e.g., natural selection under sexual reproduction can be interpreted as the Multiplicative…

Populations and Evolution · Quantitative Biology 2016-04-26 Ruta Mehta , Ioannis Panageas , Georgios Piliouras , Prasad Tetali , Vijay V. Vazirani

We consider the Moran model of population genetics with two types, mutation, and selection, and investigate the line of descent of a randomly-sampled individual from a contemporary population. We trace this ancestral line back into the…

Probability · Mathematics 2024-05-22 Ellen Baake , Enrico Di Gaspero , Fernando Cordero

In large populations, multiple beneficial mutations may be simultaneously spreading. In asexual populations, these mutations must either arise on the same background or compete against each other. In sexual populations, recombination can…

Populations and Evolution · Quantitative Biology 2013-12-19 D. B. Weissman , O. Hallatschek

In this work we introduce and analyze a linear size-structured population model with infinite states-at-birth. We model the dynamics of a population in which individuals have two distinct life-stages: an "active" phase when individuals…

Analysis of PDEs · Mathematics 2019-03-25 Jozsef Z. Farkas , Peter Hinow

Competition is the main driver of population dynamics, which shapes the genetic composition of populations and the assembly of ecological communities. Neutral models assume that all the individuals are equivalent and that the dynamics is…

Populations and Evolution · Quantitative Biology 2018-04-11 Matan Danino , Nadav M. Shnerb

We have simulated the evolution of age structured populations whose individuals represented by their diploid genomes were distributed on a square lattice. The environmental conditions on the whole territory changed simultaneously in the…

Populations and Evolution · Quantitative Biology 2009-11-05 Wojciech Waga , Marta Zawierta , Stanislaw Cebrat

We consider the effect of network structure on the evolution of a population. Models of this kind typically consider a population of fixed size and distribution. Here we consider eco-evolutionary dynamics where population size and…

Populations and Evolution · Quantitative Biology 2023-04-05 Karan Pattni , Wajid Ali , Mark Broom , Kieran J Sharkey

The time evolution of the Partridge-Barton model in the presence of the pleiotropic constraint and deleterious somatic mutations is exactly solved for arbitrary fecundity in the context of a matricial formalism. Analytical expressions for…

Statistical Mechanics · Physics 2009-10-31 Roberto N. Onody , Nazareno G. F. de Medeiros

This paper investigates a nonlinear logistic model for age-structured population dynamics. The model incorporates interdependent fertility and mortality functions within a logistic framework, offering insights into stationary solutions and…

Analysis of PDEs · Mathematics 2025-11-24 Dragos-Patru Covei

The evolutionary biology of aging is fundamental to understanding the mechanisms of aging and how to develop anti-aging treatments. Thus far most evolutionary theory concerns the genetics of aging with limited physiological integration.…

Populations and Evolution · Quantitative Biology 2025-09-22 Mirre J P Simons , Marc Tatar

Macroevolution is considered as a problem of stochastic dynamics in a system with many competing agents. Evolutionary events (speciations and extinctions) are triggered by fitness records found by random exploration of the agents' fitness…

adap-org · Physics 2017-01-11 Paolo Sibani , Michael Brandt , Preben Alstroem

The adaptive evolution of large asexual populations is generally characterized by competition between clones carrying different beneficial mutations. This interference phenomenon slows down the adaptation speed and makes the theoretical…

Populations and Evolution · Quantitative Biology 2012-12-20 Maria Rita Fumagalli , Matteo Osella , Philippe Thomen , Francois Heslot , Marco Cosentino Lagomarsino

The accumulation of deleterious mutations is driven by rare fluctuations which lead to the loss of all mutation free individuals, a process known as Muller's ratchet. Even though Muller's ratchet is a paradigmatic process in population…

Populations and Evolution · Quantitative Biology 2012-06-29 Richard A. Neher , Boris I. Shraiman

We study a family of selection-mutation models of a sexual population structured by a phenotypical trait. The main feature of these models is the asymmetric trait heredity or fecundity between the parents : we assume that each individual…

Analysis of PDEs · Mathematics 2022-04-11 Benoît Perthame , Martin Strugarek , Cécile Taing

We consider the dynamics imposed by natural selection on the populations of two competing, sexually reproducing, haploid species. In this setting, the fitness of any genome varies over time due to the changing population mix of the…

Populations and Evolution · Quantitative Biology 2024-07-18 Yuval Rabani , Leonard J. Schulman , Alistair Sinclair

Consider a mathematical model of evolutionary adaptation of fitness landscape and mutation matrix as a reaction to population changes. As a basis, we use an open quasispecies model, which is modified to include explicit death flow. We…

Populations and Evolution · Quantitative Biology 2020-11-25 Igor Samokhin , Tatiana Yakushkina , Alexander S. Bratus