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A model is proposed to minimize the total volume of the main distribution networks of fluids in relation to the organ form. The minimization analysis shows that the overall exterior form of distribution networks is a modified ellipsoid, a…

Tissues and Organs · Quantitative Biology 2007-08-13 Walton R. Gutierrez

Coordinating multi-articulated bodies to generate purposeful movement is a formidable computational challenge. Yet the human motor system performs this task robustly in dynamic, uncertain environments, despite noisy and delayed feedback,…

Neurons and Cognition · Quantitative Biology 2026-02-24 Alessandro Salatiello

Directional fluid flow in perivascular spaces surrounding cerebral arteries is hypothesized to play a key role in brain solute transport and clearance. While various drivers for pulsatile flow, such as cardiac or respiratory pulsations, are…

Fluid Dynamics · Physics 2023-10-05 Ingeborg G. Gjerde , Marie E. Rognes , Antonio L. Sanchez

Biological transport networks are highly optimized structures that ensure power-efficient distribution of fluids across various domains, including animal vasculature and plant venation. Theoretically, these networks can be described as…

Biological Physics · Physics 2025-08-01 Albert Alonso , Lars Erik J. Skjegstad , Julius B. Kirkegaard

The paper aims to study the connection between symmetries and conservation laws for the 2D Ricci flow model. The procedure starts by obtaining a set of multipliers which generates conservation laws. Then, using a general relation which…

Mathematical Physics · Physics 2011-08-30 Rodica Cimpoiasu

Topology optimization offers optimal material layouts, enabling automation in the design of devices. Given the recent advances in computer technology and additive manufacturing, topology optimization is increasingly being used to design…

Fluid Dynamics · Physics 2021-07-28 T. Phatak , K. B. Nakshatrala

The discovery of two fundamental laws concerning cellular dynamics with recursive growth is reported. First, the chemical abundances measured over many cells are found to obey a log-normal distribution and second, the relationship between…

Molecular Networks · Quantitative Biology 2007-05-23 Chikara Furusawa , Takao Suzuki , Akiko Kashiwagi , Tetsuya Yomo , Kunihiko Kaneko

Turbulence may appear as a complex process with a multitude of scales and flow patterns, but still obeys simple physical principles such as the conservation of momentum, of energy, and the maximum entropy principle. The latter states that…

Fluid Dynamics · Physics 2019-04-23 T. -W. Lee

The construction of a cost minimal network for flows obeying physical laws is an important problem for the design of electricity, water, hydrogen, and natural gas infrastructures. We formulate this problem as a mixed-integer non-linear…

Optimization and Control · Mathematics 2025-03-31 Pascal Börner , Max Klimm , Annette Lutz , Marc E. Pfetsch , Martin Skutella , Lea Strubberg

Uncovering the rules governing the nonequilibrium dynamics of the membranes that define biological cells is of central importance to understanding the physics of living systems. We theoretically and computationally investigate the behavior…

Many networked systems such as electric networks, the brain, and social networks of opinion dynamics are known to obey conservation laws. Examples of this phenomenon include the Kirchoff laws in electric networks and opinion consensus in…

Machine Learning · Statistics 2022-06-16 Anirudh Rayas , Rajasekhar Anguluri , Gautam Dasarathy

Following [21, 23], the present work investigates a new relative entropy-regularized algorithm for solving the optimal transport on a graph problem within the randomized shortest paths formalism. More precisely, a unit flow is injected into…

Machine Learning · Computer Science 2021-09-21 Sylvain Courtain , Guillaume Guex , Ilkka Kivimaki , Marco Saerens

In potential flow networks, the equilibrium flow rates are usually not proportional to the demands and flow control elements are required to regulate the flow. The control elements can broadly be classified into two types - discrete and…

Systems and Control · Electrical Eng. & Systems 2023-10-18 Varghese Kurian , Sridharakumar Narasimhan

Extremal principles are fundamental in our interpretation of phenomena in nature. One of the best known examples is the second law of thermodynamics, governing most physical and chemical systems and stating the continuous increase of…

Statistical Mechanics · Physics 2007-05-23 Dirk Helbing , Tamas Vicsek

Clar number and Fries number are two thoroughly investigated parameters of plane graphs emerging from mathematical chemistry to measure stability of organic molecules. We consider first a common generalization of these two concepts for…

Combinatorics · Mathematics 2024-06-12 Erika Bérczi-Kovács , András Frank

The notions of $r$-robustness and $(r,s)$-robustness of a network have been earlier introduced in the literature to achieve resilient consensus in the presence of misbehaving agents. However, while higher robustness levels enable networks…

Systems and Control · Electrical Eng. & Systems 2026-03-02 Haejoon Lee , Dimitra Panagou

The design of fluid channel structures of reactors or separators of chemical processes is key to enhancing the mass transfer processes inside the devices. However, the systematic design of channel topological structures is difficult for…

Fluid Dynamics · Physics 2025-03-07 Chenhui Kou , Yuhui Yin , Min Zhu , Shengkun Jia , Yiqing Luo , Xigang Yuana , Lu Lu

The second-order cone relaxation of the branch flow model (BFM) and bus injection model (BIM) variants of optimal power flow are well-known to be equivalent for radial networks. In this work we show that in meshed networks with parallel…

Optimization and Control · Mathematics 2022-03-09 Frederik Geth , Bin Liu

Modeling the dynamical flows on networks of biomolecular machines often entails computing node populations and edge fluxes with Master Equations and correlating machine performance with entropy production. But this alone is not sufficient…

Statistical Mechanics · Physics 2026-05-12 Ying-Jen Yang , Ken A. Dill

Complex networks characterized by global transport processes rely on the presence of directed paths from input to output nodes and edges, which organize in characteristic linked components. The analysis of such network-spanning structures…

Disordered Systems and Neural Networks · Physics 2015-05-13 M. Angeles Serrano , Paolo De Los Rios