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The goal of this tutorial is to promote interest in the study of random Boolean networks (RBNs). These can be very interesting models, since one does not have to assume any functionality or particular connectivity of the networks to study…

Adaptation and Self-Organizing Systems · Physics 2009-09-29 Carlos Gershenson

In the study of dynamical processes on networks, there has been intense focus on network structure -- i.e., the arrangement of edges and their associated weights -- but the effects of the temporal patterns of edges remains poorly…

Physics and Society · Physics 2015-06-16 Till Hoffmann , Mason A. Porter , Renaud Lambiotte

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

Phase transitions in equilibrium and nonequilibrium systems play a major role in the natural sciences. In dynamical networks, phase transitions organize qualitative changes in the collective behavior of coupled dynamical units. Adaptive…

Adaptation and Self-Organizing Systems · Physics 2023-02-22 Jan Fialkowski , Serhiy Yanchuk , Igor M. Sokolov , Eckehard Schöll , Georg A. Gottwald , Rico Berner

Pluripotent embryonic stem cells are of paramount importance for biomedical research thanks to their innate ability for self-renewal and differentiation into all major cell lines. The fateful decision to exit or remain in the pluripotent…

Molecular Networks · Quantitative Biology 2018-07-04 Yen Ting Lin , Peter G. Hufton , Esther J. Lee , Davit A. Potoyan

Many biological systems, such as metabolic pathways, exhibit bistability behavior: these biological systems exhibit two distinct stable states with switching between the two stable states controlled by certain conditions. Since…

Quantitative Methods · Quantitative Biology 2013-07-04 Yi Ming Zou

The research concerns the dynamics of complex autonomous Kauffman networks. The article defines and shows using simulation experiments half-chaotic networks, which exhibit features much more similar to typically modeled systems like a…

Adaptation and Self-Organizing Systems · Physics 2022-01-14 Andrzej Gecow

Complex gene regulatory networks often display emergent simple behavior. Sometimes this simplicity can be traced to a nearly equivalent energy landscape, but not always. Here, we show how a topological theory for stochastic and biochemical…

Biological Physics · Physics 2025-10-30 Aleksandra Nelson , Peter Wolynes , Evelyn Tang

We study the interplay between regular and chaotic dynamics at the critical point of a generic first-order quantum phase transition in an interacting boson model of nuclei. A classical analysis reveals a distinct behavior of the coexisting…

Nuclear Theory · Physics 2011-10-13 M. Macek , A. Leviatan

We explore some aspects of phase transitions in cellular automata. We start recalling the standard formulation of statistical mechanics of discrete systems (Ising model), illustrating the Monte Carlo approach as Markov chains and stochastic…

Statistical Mechanics · Physics 2023-12-05 Franco Bagnoli , Raul Rechtman

Many biological, technological, and social systems can be effectively described as networks of interacting subsystems. Typically, these networks are not isolated objects, but interact with their environment through both signals and…

Systems and Control · Electrical Eng. & Systems 2026-01-06 Amirhossein Nazerian , Malbor Asllani , Melvyn Tyloo , Wai Lim Ku , Francesco Sorrentino

A probabilistic Boolean network (PBN) is a discrete-time system composed of a collection of Boolean networks between which the PBN switches in a stochastic manner. This paper focuses on the study of quotients of PBNs. Given a PBN and an…

Optimization and Control · Mathematics 2021-08-02 Rui Li , Qi Zhang , Tianguang Chu

To model biological systems using networks, it is desirable to allow more than two levels of expression for the nodes and to allow the introduction of parameters. Various modeling and simulation methods addressing these needs using Boolean…

Molecular Networks · Quantitative Biology 2014-04-23 Yi Ming Zou

Firing patterns in the central nervous system often exhibit strong temporal irregularity and heterogeneity in their time averaged response properties. Previous studies suggested that these properties are outcome of an intrinsic chaotic…

Disordered Systems and Neural Networks · Physics 2015-11-25 Jonathan Kadmon , Haim Sompolinsky

We propose an analytical technique to study large fluctuations and switching from internal noise in complex networks. Using order-disorder kinetics as a generic example, we construct and analyze the most probable, or optimal path of…

Physics and Society · Physics 2017-09-07 Jason Hindes , Ira B. Schwartz

In this paper, we propose a mean-field model which attempts to bridge the gap between random Boolean networks and more realistic stochastic modeling of genetic regulatory networks. The main idea of the model is to replace all regulatory…

Quantitative Methods · Quantitative Biology 2009-11-13 M. Andrecut , S. A. Kauffman

This article is set in the field of regulation networks modeled by discrete dynamical systems. It focuses on Boolean automata networks. In such networks, there are many ways to update the states of every element. When this is done…

Discrete Mathematics · Computer Science 2015-03-19 Mathilde Noual

The dynamic stability of the Boolean networks representing a model for the gene transcriptional regulation (Kauffman model) is studied by calculating analytically and numerically the Hamming distance between two evolving configurations.…

Statistical Mechanics · Physics 2008-09-19 Deok-Sun Lee , Heiko Rieger

We study the evolution of a social network with friendly/enmity connections into a balanced state by introducing a dynamical model with an intrinsic randomness, similar to Glauber dynamics in statistical mechanics. We include the…

Physics and Society · Physics 2019-08-14 Rana Shojaei , Pouya Manshour , Afshin Montakhab

The study of the interplay between the structure and dynamics of complex multilevel systems is a pressing challenge nowadays. In this paper, we use a semi-annealed approximation to study the stability properties of Random Boolean Networks…

Physics and Society · Physics 2012-10-31 Emanuele Cozzo , Alex Arenas , Yamir Moreno
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