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Large language models (LLMs) have significantly benefited from training on diverse, high-quality task-specific data, leading to impressive performance across a range of downstream applications. Current methods often rely on human-annotated…

Computation and Language · Computer Science 2024-10-23 Qintong Li , Jiahui Gao , Sheng Wang , Renjie Pi , Xueliang Zhao , Chuan Wu , Xin Jiang , Zhenguo Li , Lingpeng Kong

This study aims to guide language model selection by investigating: 1) the necessity of finetuning versus zero-shot usage, 2) the benefits of domain-adjacent versus generic pretrained models, 3) the value of further domain-specific…

Computation and Language · Computer Science 2025-09-25 Lovedeep Gondara , Jonathan Simkin , Graham Sayle , Shebnum Devji , Gregory Arbour , Raymond Ng

Post-training of Large Language Models (LLMs) is crucial for unlocking their task generalization potential and domain-specific capabilities. However, the current LLM post-training paradigm faces significant data challenges, including the…

Computation and Language · Computer Science 2025-10-31 Junyu Luo , Bohan Wu , Xiao Luo , Zhiping Xiao , Yiqiao Jin , Rong-Cheng Tu , Nan Yin , Yifan Wang , Jingyang Yuan , Wei Ju , Ming Zhang

While large language models (LLMs) are extensively used, there are raising concerns regarding privacy, security, and copyright due to their opaque training data, which brings the problem of detecting pre-training data on the table. Current…

Computation and Language · Computer Science 2024-08-01 Anqi Zhang , Chaofeng Wu

Large language models (LLMs) have achieved remarkable performance on diverse benchmarks, yet existing evaluation practices largely rely on coarse summary metrics that obscure underlying reasoning abilities. In this work, we propose novel…

Methodology · Statistics 2026-03-17 Jia Liu , Zhiyu Xu , Yuqi Gu

In recent years, large language models (LLMs) have achieved state-of-the-art results in various biological sequence analysis tasks, such as sequence classification, structure prediction, and function prediction. Similar to advancements in…

Genomics · Quantitative Biology 2025-02-19 Wang Liang

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Large language models (LLMs) have shown impressive promise in code generation, yet their progress remains limited by the shortage of large-scale datasets that are both diverse and well-aligned with human reasoning. Most existing resources…

Machine Learning · Computer Science 2025-10-28 Amal Abed , Ivan Lukic , Jörg K. H. Franke , Frank Hutter

While large language models (LLMs) have been increasingly adopted for machine translation (MT), their performance for specialist domains such as medicine and law remains an open challenge. Prior work has shown that LLMs can be…

Computation and Language · Computer Science 2025-03-10 Bryan Li , Jiaming Luo , Eleftheria Briakou , Colin Cherry

Despite the dramatic progress in Large Language Model (LLM) development, LLMs often provide seemingly plausible but not factual information, often referred to as hallucinations. Retrieval-augmented LLMs provide a non-parametric approach to…

Computation and Language · Computer Science 2023-11-09 Sai Munikoti , Anurag Acharya , Sridevi Wagle , Sameera Horawalavithana

Large language models (LLMs) have performed well across various clinical natural language processing tasks, despite not being directly trained on electronic health record (EHR) data. In this work, we examine how popular open-source LLMs…

Computation and Language · Computer Science 2025-05-26 Furong Jia , David Sontag , Monica Agrawal

Instruction tuning is crucial for aligning Large Language Models (LLMs), yet the quality of instruction-following data varies significantly. While high-quality data is paramount, it is often scarce; conversely, abundant low-quality data is…

Computation and Language · Computer Science 2025-10-24 Zhijie Deng , Zhouan Shen , Ling Li , Yao Zhou , Zhaowei Zhu , Yanji He , Wei Wang , Jiaheng Wei

Large Language Models (LLMs) drive current AI breakthroughs despite very little being known about their internal representations. In this work, we propose to shed the light on LLMs inner mechanisms through the lens of geometry. In…

Artificial Intelligence · Computer Science 2024-07-12 Randall Balestriero , Romain Cosentino , Sarath Shekkizhar

A prior-informed large language model (LLM) driven multi-task learning framework is proposed for the unified description of multiple nuclear observables. By fine-tuning the pre-trained DeepSeek-R1-1.5B model with Low-Rank Adaptation (LoRA),…

Nuclear Theory · Physics 2026-05-29 S. J. Guo , S. Y. Wang , E. H. Wang , Z. M. Niu , Y. M. Ding

Multi-domain fine-tuning of large language models requires improving performance on target domains while preserving performance on constrained domains, such as general knowledge, instruction following, or safety evaluations. Existing data…

Machine Learning · Computer Science 2026-05-12 Eleonora Gualdoni , Sonia Laguna , Louis Bethune , Joao Monteiro , Pierre Ablin , Marco Cuturi

Tabular data is often hidden in text, particularly in medical diagnostic reports. Traditional machine learning (ML) models designed to work with tabular data, cannot effectively process information in such form. On the other hand, large…

Machine Learning · Computer Science 2023-06-09 Aleksa Bisercic , Mladen Nikolic , Mihaela van der Schaar , Boris Delibasic , Pietro Lio , Andrija Petrovic

Large Language Models (LLMs) have demonstrated great potential as generalist assistants, showcasing powerful task understanding and problem-solving capabilities. To deploy LLMs as AI assistants, it is crucial that these models exhibit…

Artificial Intelligence · Computer Science 2025-02-12 Huanqian Wang , Yang Yue , Rui Lu , Jingxin Shi , Andrew Zhao , Shenzhi Wang , Shiji Song , Gao Huang

Automatic disease diagnosis has become increasingly valuable in clinical practice. The advent of large language models (LLMs) has catalyzed a paradigm shift in artificial intelligence, with growing evidence supporting the efficacy of LLMs…

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang

Data plays a fundamental role in training Large Language Models (LLMs). Efficient data management, particularly in formulating a well-suited training dataset, is significant for enhancing model performance and improving training efficiency…

Computation and Language · Computer Science 2024-08-05 Zige Wang , Wanjun Zhong , Yufei Wang , Qi Zhu , Fei Mi , Baojun Wang , Lifeng Shang , Xin Jiang , Qun Liu