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Parameter-Efficient Fine-Tuning (PEFT) effectively adapts pre-trained transformers to downstream tasks. However, the optimization of tasks performance often comes at the cost of generalizability in fine-tuned models. To address this issue,…

Machine Learning · Computer Science 2026-03-09 Yao Ni , Shan Zhang , Piotr Koniusz

Machine Learning Interatomic Potentials (MLIPs) enable accurate large-scale atomistic simulations, yet improving their expressive capacity efficiently remains challenging. Here we systematically develop Mixture-of-Experts (MoE) and…

Chemical Physics · Physics 2026-03-13 Yuzhi Liu , Duo Zhang , Anyang Peng , Weinan E , Linfeng Zhang , Han Wang

Multimodal pretraining is effective for building general-purpose representations, but in many practical deployments, only one modality is heavily used during downstream fine-tuning. Standard pretraining strategies treat all modalities…

Machine Learning · Computer Science 2026-01-30 Atik Faysal , Mohammad Rostami , Reihaneh Gh. Roshan , Nikhil Muralidhar , Huaxia Wang

Atomic vibrations play a critical role in phonon-assisted electron transitions at defects in solids. However, accurate phonon calculations in defect systems are often hindered by the high computational cost of large-supercell…

Materials Science · Physics 2025-12-19 Junjie Zhou , Xinpeng Li , Menglin Huang , Shiyou Chen

Most uses of machine learning today involve training a model from scratch for a particular task, or sometimes starting with a model pretrained on a related task and then fine-tuning on a downstream task. Both approaches offer limited…

Machine Learning · Computer Science 2022-05-26 Andrea Gesmundo , Jeff Dean

Accurate time series forecasting models are often compromised by data drift, where underlying data distributions change over time, leading to significant declines in prediction performance. To address this challenge, this study proposes an…

Systems and Control · Electrical Eng. & Systems 2025-12-30 Nikhil Pawar , Guilherme Vieira Hollweg , Akhtar Hussain , Wencong Su , Van-Hai Bui

Machine learning (ML) based models have greatly enhanced the traditional materials discovery and design pipeline. Specifically, in recent years, surrogate ML models for material property prediction have demonstrated success in predicting…

Materials Science · Physics 2022-01-21 Prathik R Kaundinya , Kamal Choudhary , Surya R. Kalidindi

In recent years, machine learning interatomic potentials (MLIPs) have attracted significant attention as a method that enables large-scale, long-time atomistic simulations while maintaining accuracy comparable to electronic structure…

Materials Science · Physics 2025-03-27 Yuta Yoshimoto , Naoki Matsumura , Yuto Iwasaki , Hiroshi Nakao , Yasufumi Sakai

Twisted layered van-der-Waals materials often exhibit unique electronic and optical properties absent in their non-twisted counterparts. Unfortunately, predicting such properties is hindered by the difficulty in determining the atomic…

Understanding and predicting the behavior of liquid matter across length scales, using only the microscopic interactions encoded in the Schr\"odinger equation, remains a central challenge in the physical sciences. Achieving this goal…

Chemical Physics · Physics 2026-03-24 Anna T. Bui , Stephen J. Cox

Molecular dynamics (MD) employing machine-learned interatomic potentials (MLIPs) serve as an efficient, urgently needed complement to ab initio molecular dynamics (aiMD). By training these potentials on data generated from ab initio…

Materials Science · Physics 2024-09-19 Kisung Kang , Thomas A. R. Purcell , Christian Carbogno , Matthias Scheffler

The vastness of chemical space makes generalization a central challenge in the development of machine learning interatomic potentials (MLIPs). While MLIPs could enable large-scale atomistic simulations with near-quantum accuracy, their…

Chemical Physics · Physics 2026-03-20 Michal Sanocki , Julija Zavadlav

Machine Learning (ML) approximations to Density Functional Theory (DFT) potential energy surfaces (PESs) are showing great promise for reducing the computational cost of accurate molecular simulations, but at present they are not applicable…

Chemical Physics · Physics 2020-03-05 Xiaowei Xie , Kristin A. Persson , David W. Small

In this paper, we present a semi-supervised fine-tuning approach designed to improve the performance of pre-trained foundation models on downstream tasks with limited labeled data. By leveraging content-style decomposition within an…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Mariia Drozdova , Vitaliy Kinakh , Yury Belousov , Erica Lastufka , Slava Voloshynovskiy

Structure optimization, which yields the relaxed structure (minimum-energy state), is essential for reliable materials property calculations, yet traditional ab initio approaches such as density-functional theory (DFT) are computationally…

Materials Science · Physics 2025-11-18 Ziduo Yang , Yi-Ming Zhao , Xian Wang , Wei Zhuo , Xiaoqing Liu , Lei Shen

The power of foundation models (FMs) lies in their capacity to learn highly expressive representations that can be adapted to a broad spectrum of tasks. However, these pretrained models require additional training stages to become effective…

Machine Learning · Computer Science 2025-10-24 Jacob L. Block , Sundararajan Srinivasan , Liam Collins , Aryan Mokhtari , Sanjay Shakkottai

Accurate prediction of drug-target binding affinity can accelerate drug discovery by prioritizing promising compounds before costly wet-lab screening. While deep learning has advanced this task, most models fuse ligand and protein…

Machine Learning · Computer Science 2025-09-26 Mohammadsaleh Refahi , Bahrad A. Sokhansanj , James R. Brown , Gail Rosen

Accurate beam alignment is a critical challenge in XL-MIMO systems, especially in the near-field regime, where conventional far-field assumptions no longer hold. Although 2D grid-based codebooks in the polar domain are widely accepted for…

Signal Processing · Electrical Eng. & Systems 2025-02-27 Hongjun Heo , Wan Choi

Prompt learning has emerged as a promising paradigm for adapting pre-trained vision-language models (VLMs) to few-shot whole slide image (WSI) classification by aligning visual features with textual representations, thereby reducing…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Junjie Zhou , Wei Shao , Yagao Yue , Wei Mu , Peng Wan , Qi Zhu , Daoqiang Zhang

Machine Learning (ML)-based force fields are attracting ever-increasing interest due to their capacity to span spatiotemporal scales of classical interatomic potentials at quantum-level accuracy. They can be trained based on high-fidelity…

Chemical Physics · Physics 2024-06-03 Sebastien Röcken , Julija Zavadlav