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We study how reliably sparse autoencoders (SAEs) support claims about reasoning-related internal features in large language models. We first give a stylized analysis showing that sparsity-regularized decoding can preferentially retain…

Machine Learning · Computer Science 2026-05-19 George Ma , Zhongyuan Liang , Irene Y. Chen , Somayeh Sojoudi

We present InfoVAE-Med3D, a latent-representation learning approach for 3D brain MRI that targets interpretable biomarkers of cognitive decline. Standard statistical models and shallow machine learning often lack power, while most deep…

Clinical decision-making relies on the integrated analysis of medical images and the associated clinical reports. While Vision-Language Models (VLMs) can offer a unified framework for such tasks, they can exhibit strong biases toward one…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 David Restrepo , Ira Ktena , Maria Vakalopoulou , Stergios Christodoulidis , Enzo Ferrante

Emergency triage decisions are made under severe information constraints, yet most data-driven deterioration models are evaluated using signals unavailable during initial assessment. We present a leakage-aware benchmarking framework for…

Computers and Society · Computer Science 2026-03-31 KMA Solaiman , Joshua Sebastian , Karma Tobden

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Recent work in Mechanistic Interpretability (MI) has enabled the identification and intervention of internal features in Large Language Models (LLMs). However, a persistent challenge lies in linking such internal features to the reliable…

Computation and Language · Computer Science 2026-04-08 Ruikang Zhang , Shuo Wang , Qi Su

Global healthcare providers are exploring use of large language models (LLMs) to provide medical advice to the public. LLMs now achieve nearly perfect scores on medical licensing exams, but this does not necessarily translate to accurate…

Human bilinguals often use similar brain regions to process multiple languages, depending on when they learned their second language and their proficiency. In large language models (LLMs), how are multiple languages learned and encoded? In…

Computation and Language · Computer Science 2025-05-26 Jannik Brinkmann , Chris Wendler , Christian Bartelt , Aaron Mueller

Large Language Models (LLMs) have achieved high accuracy on medical question-answer (QA) benchmarks, yet their capacity for flexible clinical reasoning has been debated. Here, we asked whether advances in reasoning LLMs improve their…

Computation and Language · Computer Science 2026-01-21 Kie Shidara , Preethi Prem , Jonathan Kim , Anna Podlasek , Feng Liu , Ahmed Alaa , Danilo Bernardo

Surgical co-management (SCM) is an evidence-based model in which hospitalists jointly manage medically complex perioperative patients alongside surgical teams. Despite its clinical and financial value, SCM is limited by the need to manually…

Large Language Models (LLMs) are increasingly used in tasks such as psychological text analysis and decision-making in automated workflows. However, their reliability remains a concern due to potential biases inherited from their training…

Computation and Language · Computer Science 2025-04-29 Yi-Long Lu , Chunhui Zhang , Wei Wang

Large language models (LLMs) have recently shown strong progress on scientific reasoning, yet two major bottlenecks remain. First, explicit retrieval fragments reasoning, imposing a hidden "tool tax" of extra tokens and steps. Second,…

Large language models (LLMs) are increasingly applied in biomedical domains, yet their reliability in drug-safety prediction remains underexplored. In this work, we investigate whether LLMs incorporate socio-demographic information into…

Computation and Language · Computer Science 2025-10-17 Siying Liu , Shisheng Zhang , Indu Bala

Large Language Models (LLMs) are being adopted across a wide range of tasks, including decision-making processes in industries where bias in AI systems is a significant concern. Recent research indicates that LLMs can harbor implicit biases…

Computation and Language · Computer Science 2024-10-18 Divyanshu Kumar , Umang Jain , Sahil Agarwal , Prashanth Harshangi

Current medical language model (LM) benchmarks often over-simplify the complexities of day-to-day clinical practice tasks and instead rely on evaluating LMs on multiple-choice board exam questions. In psychiatry especially, these challenges…

Large language models (LLMs) are increasingly used as automatic judges to evaluate system outputs in tasks such as reasoning, question answering, and creative writing. A faithful judge should base its verdicts solely on content quality,…

Computation and Language · Computer Science 2026-02-10 Arash Marioriyad , Omid Ghahroodi , Ehsaneddin Asgari , Mohammad Hossein Rohban , Mahdieh Soleymani Baghshah

This study introduces an evaluation framework for multimodal models in medical imaging diagnostics. We developed a pipeline incorporating data preprocessing, model inference, and preference-based evaluation, expanding an initial set of 500…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Cailian Ruan , Chengyue Huang , Yahe Yang

Pulmonary embolism (PE) registries accelerate practice-improving research but depend on resource-intensive manual abstraction of radiology reports. We evaluated whether openly available large-language models (LLMs) can automate concept…

Large language models (LLMs) increasingly serve as automated evaluators, yet they suffer from "self-preference bias": a tendency to favor their own outputs over those of other models. This bias undermines fairness and reliability in…

Computation and Language · Computer Science 2025-09-05 Dani Roytburg , Matthew Bozoukov , Matthew Nguyen , Jou Barzdukas , Simon Fu , Narmeen Oozeer

Large language models (LLMs) encode a diverse range of linguistic features within their latent representations, which can be harnessed to steer their output toward specific target characteristics. In this paper, we modify the internal…

Computation and Language · Computer Science 2025-02-27 Sumanta Bhattacharyya , Pedram Rooshenas
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