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Clinical trials are essential to drug development but time-consuming, costly, and prone to failure. Accurate trial outcome prediction based on historical trial data promises better trial investment decisions and more trial success. Existing…

Machine Learning · Computer Science 2023-04-12 Zifeng Wang , Cao Xiao , Jimeng Sun

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

Machine Learning · Computer Science 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Spatial transcriptomics (ST) technologies enable gene expression profiling with spatial resolution, offering unprecedented insights into tissue organization and disease heterogeneity. However, current analysis methods often struggle with…

Spiking neural networks are motivated from principles of neural systems and may possess unexplored advantages in the context of machine learning. A class of \textit{convolutional spiking neural networks} is introduced, trained to detect…

Neural and Evolutionary Computing · Computer Science 2018-08-27 Daniel J. Saunders , Hava T. Siegelmann , Robert Kozma , Miklós Ruszinkó

Secure speculation schemes have shown great promise in the war against speculative side-channel attacks, and will be a key building block for developing secure, high-performance architectures moving forward. As the field matures, the need…

Cryptography and Security · Computer Science 2025-04-10 Amund Bergland Kvalsvik , Magnus Själander

To render a sequence testable, namely capable of identifying and detecting errors, it is necessary to apply a transformation that increases its length by introducing statistical dependence among symbols, as commonly exemplified by the…

Information Theory · Computer Science 2025-07-08 Aida Koch , Alix Petit

Many previous works in spike sorting study spike classification and compression independently. In this paper, a novel algorithm is proposed called MetaSort to address these two problems. To deal with compression, a novel adaptive level…

Signal Processing · Electrical Eng. & Systems 2026-03-10 Luca M. Meyer , Majid Zamani

We study the distributed minimum spanning tree (MST) problem, a fundamental problem in distributed computing. It is well-known that distributed MST can be solved in $\tilde{O}(D+\sqrt{n})$ rounds in the standard CONGEST model (where $n$ is…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-20 John Augustine , William K. Moses , Gopal Pandurangan

Large reasoning models (LRMs) have attracted much attention due to their exceptional performance. However, their performance mainly stems from thinking, a long Chain of Thought (CoT), which significantly increase computational overhead. To…

Artificial Intelligence · Computer Science 2026-01-09 Siyuan Gan , Jiaheng Liu , Boyan Wang , Tianpei Yang , Runqing Miao , Yuyao Zhang , Fanyu Meng , Junlan Feng , Linjian Meng , Jing Huo , Yang Gao

Processing graphs with temporal information (the temporal graphs) has become increasingly important in the real world. In this paper, we study efficient solutions to temporal graph applications using new algorithms for Incremental Minimum…

Data Structures and Algorithms · Computer Science 2025-05-13 Xiangyun Ding , Yan Gu , Yihan Sun

In-memory computing promises to overcome the von Neumann bottleneck in computer systems by performing computations directly within the memory. Previous research has suggested using Spin-Transfer Torque RAM (STT-RAM) for in-memory computing…

Computers and Society · Computer Science 2024-07-30 Dhruv Gajaria , Kevin Antony Gomez , Tosiron Adegbija

In this paper we generalize the definition of "Search Trees" (ST) to enable reference values other than the key of prior inserted nodes. The idea builds on the assumption an $n$-node AVL (or Red-Black) requires to assure $O(\log_2n)$…

Data Structures and Algorithms · Computer Science 2018-04-04 Saulo Queiroz

Multinomial processing tree (MPT) models are tools for disentangling the contributions of latent cognitive processes in a given experimental paradigm. The present note analyzes MPT models subject to order constraints on subsets of its…

Applications · Statistics 2014-11-11 Karl Christoph Klauer , Henrik Singmann , David Kellen

In this paper, we propose an alternative method to estimate room layouts of cluttered indoor scenes. This method enjoys the benefits of two novel techniques. The first one is semantic transfer (ST), which is: (1) a formulation to integrate…

Computer Vision and Pattern Recognition · Computer Science 2017-07-04 Hao Zhao , Ming Lu , Anbang Yao , Yiwen Guo , Yurong Chen , Li Zhang

In the modern era of multi-core systems, the main aim is to utilize the cores properly. This utilization can be done by concurrent programming. But developing a flawless and well-organized concurrent program is difficult. Software…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-06 Chirag Juyal , Sandeep Kulkarni , Sweta Kumari , Sathya Peri , Archit Somani

Hashing methods have been widely used for efficient similarity retrieval on large scale image database. Traditional hashing methods learn hash functions to generate binary codes from hand-crafted features, which achieve limited accuracy…

Computer Vision and Pattern Recognition · Computer Science 2017-11-08 Jian Zhang , Yuxin Peng

Sequence set is a widely-used type of data source in a large variety of fields. A typical example is protein structure prediction, which takes an multiple sequence alignment (MSA) as input and aims to infer structural information from it.…

Biomolecules · Quantitative Biology 2019-06-27 Fusong Ju , Jianwei Zhu , Guozheng Wei , Qi Zhang , Shiwei Sun , Dongbo Bu

While Transformers have achieved remarkable success in LLMs through superior scalability, their application in industrial-scale ranking models remains nascent, hindered by the challenges of high feature sparsity and low label density. In…

Information Retrieval · Computer Science 2026-03-05 Chunqi Wang , Bingchao Wu , Taotian Pang , Jiahao Wang , Jie Yang , Jia Liu , Hao Zhang , Hai Zhu , Lei Shen , Shizhun Wang , Bing Wang , Xiaoyi Zeng

Supervised hashing methods are widely-used for nearest neighbor search in computer vision applications. Most state-of-the-art supervised hashing approaches employ batch-learners. Unfortunately, batch-learning strategies can be inefficient…

Computer Vision and Pattern Recognition · Computer Science 2015-11-11 Fatih Cakir , Sarah Adel Bargal , Stan Sclaroff

This paper focuses on the statistical analysis of shapes of data objects called shape graphs, a set of nodes connected by articulated curves with arbitrary shapes. A critical need here is a constrained registration of points (nodes to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 Shenyuan Liang , Mauricio Pamplona Segundo , Sathyanarayanan N. Aakur , Sudeep Sarkar , Anuj Srivastava