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Drug discovery frequently loses momentum when data, expertise, and tools are scattered, slowing design cycles. To shorten this loop we built a hierarchical, tool using agent framework that automates molecular optimisation. A Principal…

Machine Learning · Computer Science 2025-08-06 Atabey Ünlü , Phil Rohr , Ahmet Celebi

Recent benchmarks for Large Language Model (LLM) agents mainly evaluate reasoning, planning, and execution. However, memory is also essential for agents, as it enables them to store, update, and retrieve information over time. This ability…

Computation and Language · Computer Science 2026-05-19 Yuyao Wang , Zhongjian Zhang , Mo Chi , Kaichi Yu , Yuhan Li , Miao Peng , Bing Tong , Chen Zhang , Yan Zhou , Jia Li

Neural IR has advanced through two distinct paths: entity-oriented approaches leveraging knowledge graphs and multi-vector models capturing fine-grained semantics. We introduce QDER, a neural re-ranking model that unifies these approaches…

Information Retrieval · Computer Science 2025-10-14 Shubham Chatterjee , Jeff Dalton

We unveil that internal representations in large language models (LLMs) serve as reliable proxies of learned knowledge, and propose RECALL, a novel representation-aware model merging framework for continual learning without access to…

Computation and Language · Computer Science 2025-10-24 Bowen Wang , Haiyuan Wan , Liwen Shi , Chen Yang , Peng He , Yue Ma , Haochen Han , Wenhao Li , Tiao Tan , Yongjian Li , Fangming Liu , Yifan Gong , Sheng Zhang

Multi-agent LLM systems on edge devices face a memory management problem: device RAM is too small to hold every agent's KV cache simultaneously. On Apple M4 Pro with 10.2 GB of cache budget, only 3 agents fit at 8K context in FP16. A…

Machine Learning · Computer Science 2026-03-06 Yakov Pyotr Shkolnikov

Federated learning on edge devices must cope with non-IID client data and tight memory budgets. Adaptive optimizers like Adam stabilize training under data heterogeneity but require storing full-precision momentum and variance states, often…

Machine Learning · Computer Science 2026-05-19 Vedant Waykole , Haroon R. Lone

We show that it is feasible to perform entity linking by training a dual encoder (two-tower) model that encodes mentions and entities in the same dense vector space, where candidate entities are retrieved by approximate nearest neighbor…

Computation and Language · Computer Science 2019-09-24 Daniel Gillick , Sayali Kulkarni , Larry Lansing , Alessandro Presta , Jason Baldridge , Eugene Ie , Diego Garcia-Olano

Multimodal Large Language Models (MLLMs) have demonstrated substantial value in unified text-image understanding and reasoning, primarily by converting images into sequences of patch-level tokens that align with their architectural…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Xinliang Zhang , Lei Zhu , Hangzhou He , Shuang Zeng , Ourui Fu , Jiakui Hu , Zhengjian Yao , Yanye Lu

Large Language Models (LLMs) have shown strong potential as conversational agents. Yet, their effectiveness remains limited by deficiencies in robust long-term memory, particularly in complex, long-term web-based services such as online…

Computation and Language · Computer Science 2026-02-03 Tiantian Chen , Jiaqi Lu , Ying Shen , Lin Zhang

Despite the significant progress made by transformer models in machine reading comprehension tasks, they still fall short in handling complex reasoning tasks due to the absence of explicit knowledge in the input sequence. To address this…

Computation and Language · Computer Science 2024-01-17 Shima Foolad , Kourosh Kiani

Large language model agents are becoming increasingly capable at web-centric tasks such as information retrieval, complex reasoning. These emerging capabilities have given rise to surge research interests in developing LLM agent for…

Computation and Language · Computer Science 2026-04-02 Yu Li , Lehui Li , Lin Chen , Qingmin Liao , Fengli Xu , Yong Li

This paper proposes Edge-FIT (Federated Instruction Tuning on the Edge), a scalable framework for Federated Instruction Tuning (FIT) of Large Language Models (LLMs). Traditional Federated Learning (TFL) methods, like FedAvg, fail when…

Machine Learning · Computer Science 2025-10-07 Vinay Venkatesh , Vamsidhar R Kamanuru , Lav Kumar , Nikita Kothari

Large Language Models (LLMs) have demonstrated strong capabilities in biomedical question answering, yet their tendency to generate plausible but unverified claims poses serious risks in clinical settings. To mitigate these risks, the TREC…

Information Retrieval · Computer Science 2026-03-19 Soumya Ranjan Sahoo , Gagan N. , Sanand Sasidharan , Divya Bharti

The rapid emergence of new entities -- driven by cultural shifts, evolving trends, and personalized user data -- poses a significant challenge for existing Speech Large Language Models (Speech LLMs). While these models excel at general…

Artificial Intelligence · Computer Science 2026-02-06 Peidong Wang

LLM-based coding agents rely on \emph{skills}, pre-packaged instruction sets that extend agent capabilities, yet every token of skill content injected into the context window incurs both monetary cost and attention dilution. To understand…

Software Engineering · Computer Science 2026-04-01 Yudong Gao , Zongjie Li , Yuanyuanyuan , Zimo Ji , Pingchuan Ma , Shuai Wang

As AI agents powered by large language models (LLMs) increasingly use external tools for high-stakes decisions, a critical reliability question arises: how do errors propagate across sequential tool calls? We introduce the first theoretical…

Artificial Intelligence · Computer Science 2026-02-17 Flint Xiaofeng Fan , Cheston Tan , Roger Wattenhofer , Yew-Soon Ong

Large Language Models (LLMs) are increasingly used as autonomous agents in complex, long-horizon applications, where effective memory is critical for sustained performance. Yet existing memory benchmarks are largely dialogue-centric, while…

AI agents increasingly operate over extended time horizons, yet their ability to retain, organize, and recall multimodal experiences remains a critical bottleneck. Building effective lifelong memory requires navigating a vast design space…

Artificial Intelligence · Computer Science 2026-04-03 Jiaqi Liu , Zipeng Ling , Shi Qiu , Yanqing Liu , Siwei Han , Peng Xia , Haoqin Tu , Zeyu Zheng , Cihang Xie , Charles Fleming , Mingyu Ding , Huaxiu Yao

Joint entity and relation extraction framework constructs a unified model to perform entity recognition and relation extraction simultaneously, which can exploit the dependency between the two tasks to mitigate the error propagation problem…

Computation and Language · Computer Science 2021-04-19 Yongliang Shen , Xinyin Ma , Yechun Tang , Weiming Lu

Text embeddings are central to modern information retrieval and Retrieval-Augmented Generation (RAG). While dense models derived from Large Language Models (LLMs) dominate current practice, recent work has explored quantum-inspired…

Information Retrieval · Computer Science 2026-04-14 Dario Maio