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The crux of molecular property prediction is to generate meaningful representations of the molecules. One promising route is to exploit the molecular graph structure through Graph Neural Networks (GNNs). It is well known that both atoms and…

Quantitative Methods · Quantitative Biology 2020-06-15 Hehuan Ma , Yatao Bian , Yu Rong , Wenbing Huang , Tingyang Xu , Weiyang Xie , Geyan Ye , Junzhou Huang

This paper surveys the trend of leveraging machine learning to solve mixed integer programming (MIP) problems. Theoretically, MIP is an NP-hard problem, and most of the combinatorial optimization (CO) problems can be formulated as the MIP.…

Artificial Intelligence · Computer Science 2022-03-08 Jiayi Zhang , Chang Liu , Junchi Yan , Xijun Li , Hui-Ling Zhen , Mingxuan Yuan

Machine-learning (ML) models in polymer science typically treat a polymer as a single, perfectly defined molecular graph, even though real materials consist of stochastic ensembles of chains with distributed lengths. This mismatch between…

Machine Learning · Computer Science 2025-12-16 Khalid Ferji

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches…

Machine Learning · Computer Science 2026-03-24 Long Xu , Junping Guo , Jianbo Zhao , Jianbo Lu , Yuzhong Peng

Explicit machine learning-based model predictive control (explicit ML-MPC) has been developed to reduce the real-time computational demands of traditional ML-MPC. However, the evaluation of candidate control actions in explicit ML-MPC can…

Optimization and Control · Mathematics 2024-08-14 Wenlong Wang , Haohao Zhang , Yujia Wang , Yuhe Tian , Zhe Wu

Dense retrieval models use bi-encoder network architectures for learning query and document representations. These representations are often in the form of a vector representation and their similarities are often computed using the dot…

Information Retrieval · Computer Science 2023-05-01 Hamed Zamani , Michael Bendersky

A simple framework Probabilistic Multi-view Graph Embedding (PMvGE) is proposed for multi-view feature learning with many-to-many associations so that it generalizes various existing multi-view methods. PMvGE is a probabilistic model for…

Machine Learning · Statistics 2018-06-12 Akifumi Okuno , Tetsuya Hada , Hidetoshi Shimodaira

We transform join ordering into a mixed integer linear program (MILP). This allows to address query optimization by mature MILP solver implementations that have evolved over decades and steadily improved their performance. They offer…

Databases · Computer Science 2015-11-09 Immanuel Trummer , Christoph Koch

Mixup is a data augmentation technique that relies on training using random convex combinations of data points and their labels. In recent years, Mixup has become a standard primitive used in the training of state-of-the-art image…

Machine Learning · Computer Science 2024-11-06 Muthu Chidambaram , Xiang Wang , Chenwei Wu , Rong Ge

Scientific Machine Learning is transforming traditional engineering industries by enhancing the efficiency of existing technologies and accelerating innovation, particularly in modeling chemical reactions. Despite recent advancements, the…

Machine Learning · Computer Science 2024-08-21 Imran Nasim , Joaõ Lucas de Sousa Almeida

Geometric shape classification of vector polygons remains a challenging task in spatial analysis. Previous studies have primarily focused on deep learning approaches for rasterized vector polygons, while the study of discrete polygon…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Zexian Huang , Kourosh Khoshelham , Martin Tomko

Molecular property prediction refers to the task of labeling molecules with some biochemical properties, playing a pivotal role in the drug discovery and design process. Recently, with the advancement of machine learning, deep…

Molecular Networks · Quantitative Biology 2024-01-10 Zeyu Wang , Tianyi Jiang , Jinhuan Wang , Qi Xuan

This paper studies the high-dimensional mixed linear regression (MLR) where the output variable comes from one of the two linear regression models with an unknown mixing proportion and an unknown covariance structure of the random…

Methodology · Statistics 2020-11-10 Linjun Zhang , Rong Ma , T. Tony Cai , Hongzhe Li

This work introduces a framework to address the computational complexity inherent in Mixed-Integer Programming (MIP) models by harnessing the potential of deep learning. By employing deep learning, we construct problem-specific heuristics…

Optimization and Control · Mathematics 2024-05-13 Niki Triantafyllou , Maria M. Papathanasiou

Conventional vision algorithms adopt a single type of feature or a simple concatenation of multiple features, which is always represented in a high-dimensional space. In this paper, we propose a novel unsupervised spectral embedding…

Computer Vision and Pattern Recognition · Computer Science 2015-08-05 Mengyang Yu , Li Liu , Ling Shao

Due to their weak inductive bias, Multi-Layer Perceptrons (MLPs) have subpar performance at low-compute levels compared to standard architectures such as convolution-based networks (CNN). Recent work, however, has shown that the performance…

Machine Learning · Computer Science 2024-10-15 Sean Wu , Jordan Hong , Keyu Bai , Gregor Bachmann

We study logit-based multi-purchase choice models and develop an exact solution methodology for the resulting assortment optimization problems, which we show are NP-hard to approximate. We introduce a hypergraph representation that captures…

Optimization and Control · Mathematics 2026-03-30 Taotao He , Zhongqi Wu , Yating Zhang

We present ChemXploreML, a modular desktop application designed for machine learning-based molecular property prediction. The framework's flexible architecture allows integration of any molecular embedding technique with modern machine…

Chemical Physics · Physics 2025-05-14 Aravindh Nivas Marimuthu , Brett A. McGuire

A data-driven model augmentation framework, referred to as Weakly-coupled Integrated Inference and Machine Learning (IIML), is presented to improve the predictive accuracy of physical models. In contrast to parameter calibration, this work…

Computational Engineering, Finance, and Science · Computer Science 2022-07-25 Vishal Srivastava , Valentin Sulzer , Peyman Mohtat , Jason B. Siegel , Karthik Duraisamy

Randomized neural networks for representation learning have consistently achieved prominent results in texture recognition tasks, effectively combining the advantages of both traditional techniques and learning-based approaches. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-06 Ricardo T. Fares , Lucas C. Ribas