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Objective: The growing availability of large-scale observational clinical datasets and challenges in conducting randomized controlled trials have spurred enthusiasm in using causal machine learning (ML) for causal inference in observational…

In contemporary scientific research, understanding the distinction between correlation and causation is crucial. While correlation is a widely used analytical standard, it does not inherently imply causation. This paper addresses the…

Machine Learning · Computer Science 2023-12-27 Cao Zhihao , Qu Hongchun

Causal inference is a vital aspect of multiple scientific disciplines and is routinely applied to high-impact applications such as medicine. However, evaluating the performance of causal inference methods in real-world environments is…

Machine Learning · Computer Science 2023-07-04 Mathieu Chevalley , Yusuf Roohani , Arash Mehrjou , Jure Leskovec , Patrick Schwab

Causal discovery studies the problem of mining causal relationships between variables from data, which is of primary interest in science. During the past decades, significant amount of progresses have been made toward this fundamental data…

Artificial Intelligence · Computer Science 2016-11-28 Kui Yu , Jiuyong Li , Lin Liu

A key goal of empirical research in software engineering is to assess practical significance, which answers whether the observed effects of some compared treatments show a relevant difference in practice in realistic scenarios. Even though…

Software Engineering · Computer Science 2024-10-03 Richard Torkar , Carlo A. Furia , Robert Feldt , Francisco Gomes de Oliveira Neto , Lucas Gren , Per Lenberg , Neil A. Ernst

Substantial advances in Bayesian methods for causal inference have been developed in recent years. We provide an introduction to Bayesian inference for causal effects for practicing statisticians who have some familiarity with Bayesian…

Methodology · Statistics 2023-12-12 Arman Oganisian , Jason A. Roy

As large language models (LLMs) witness increasing deployment in complex, high-stakes decision-making scenarios, it becomes imperative to ground their reasoning in causality rather than spurious correlations. However, strong performance on…

Artificial Intelligence · Computer Science 2026-02-24 Yuzhe Wang , Yaochen Zhu , Jundong Li

Large Language Models (LLMs) have been used as experts to infer causal graphs, often by repeatedly applying a pairwise prompt that asks about the causal relationship of each variable pair. However, such experts, including human domain…

Artificial Intelligence · Computer Science 2025-04-09 Aniket Vashishtha , Abbavaram Gowtham Reddy , Abhinav Kumar , Saketh Bachu , Vineeth N Balasubramanian , Amit Sharma

Estimating treatment effects (TE) from observational data is a critical yet complex task in many fields, from healthcare and economics to public policy. While recent advances in machine learning and causal inference have produced powerful…

Machine Learning · Computer Science 2025-08-15 Jeroen Berrevoets , Julianna Piskorz , Robert Davis , Harry Amad , Jim Weatherall , Mihaela van der Schaar

Accurate prediction of Remaining Useful Life (RUL) for complex industrial machinery is critical for the reliability and maintenance of mechatronic systems, but it is challenged by high-dimensional, noisy sensor data. We propose the…

Signal Processing · Electrical Eng. & Systems 2025-03-25 Yan Chen , Cheng Liu

Causal machine learning has the potential to revolutionize decision-making by combining the predictive power of machine learning algorithms with the theory of causal inference. However, these methods remain underutilized by the broader…

This article presents a novel method for causal discovery with generalized structural equation models suited for analyzing diverse types of outcomes, including discrete, continuous, and mixed data. Causal discovery often faces challenges…

Methodology · Statistics 2023-10-26 Minjie Wang , Xiaotong Shen , Wei Pan

Causal inference in observational studies with high-dimensional covariates presents significant challenges. We introduce CausalBGM, an AI-powered Bayesian generative modeling approach that captures the causal relationship among covariates,…

Machine Learning · Statistics 2026-02-23 Qiao Liu , Wing Hung Wong

Causal models bring many benefits to decision-making systems (or agents) by making them interpretable, sample-efficient, and robust to changes in the input distribution. However, spurious correlations can lead to wrong causal models and…

Machine Learning · Computer Science 2020-12-09 Sergei Volodin , Nevan Wichers , Jeremy Nixon

Over the past few decades, addressing "spatial confounding" has become a major topic in spatial statistics. However, the literature has provided conflicting definitions, and many proposed solutions are tied to specific analysis models and…

Methodology · Statistics 2024-10-14 Brian Gilbert , Abhirup Datta , Joan A. Casey , Elizabeth L. Ogburn

Causal inference is a statistical paradigm for quantifying causal effects using observational data. It is a complex process, requiring multiple steps, iterations, and collaborations with domain experts. Analysts often rely on visualizations…

Human-Computer Interaction · Computer Science 2023-03-02 Grace Guo , Ehud Karavani , Alex Endert , Bum Chul Kwon

Causal inference from observational data can be viewed as a missing data problem arising from a hypothetical population-scale randomized trial matched to the observational study. This links a target trial protocol with a corresponding…

Methodology · Statistics 2022-07-27 Andrew Yiu , Edwin Fong , Stephen Walker , Chris Holmes

Many statistical problems in causal inference involve a probability distribution other than the one from which data are actually observed; as an additional complication, the object of interest is often a marginal quantity of this other…

Methodology · Statistics 2023-10-24 Robin J. Evans , Vanessa Didelez

Background. Starting from the 1960s, practitioners and researchers have looked for ways to empirically investigate new technologies such as inspecting the effectiveness of new methods, tools, or practices. With this purpose, the empirical…

Software Engineering · Computer Science 2019-08-14 Nyyti Saarimäki

Causal decision making (CDM) based on machine learning has become a routine part of business. Businesses algorithmically target offers, incentives, and recommendations to affect consumer behavior. Recently, we have seen an acceleration of…

Machine Learning · Statistics 2021-10-01 Carlos Fernández-Loría , Foster Provost