English
Related papers

Related papers: PhAME: Phenotype-Aware Molecular Editing via Laten…

200 papers

Generative modeling frameworks have emerged as an effective approach to capture high-dimensional image distributions from large datasets without requiring domain-specific knowledge, a capability essential for longitudinal disease…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Ayantika Das , Arunima Sarkar , Keerthi Ram , Mohanasankar Sivaprakasam

Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower…

Machine Learning · Computer Science 2023-06-12 Pedro Henrique da Costa Avelar , Min Wu , Sophia Tsoka

Latent diffusion models have exhibited considerable potential in generative tasks. Watermarking is considered to be an alternative to safeguard the copyright of generative models and prevent their misuse. However, in the context of model…

Cryptography and Security · Computer Science 2025-02-20 Liangqi Lei , Keke Gai , Jing Yu , Liehuang Zhu , Qi Wu

Feature Transformation (FT) crafts new features from original ones via mathematical operations to enhance dataset expressiveness for downstream models. However, existing FT methods exhibit critical limitations: discrete search struggles…

Machine Learning · Computer Science 2025-05-22 Nanxu Gong , Zijun Li , Sixun Dong , Haoyue Bai , Wangyang Ying , Xinyuan Wang , Yanjie Fu

Generative AI presents chemists with novel ideas for drug design and facilitates the exploration of vast chemical spaces. Diffusion models (DMs), an emerging tool, have recently attracted great attention in drug R\&D. This paper…

Biomolecules · Quantitative Biology 2025-07-14 Peining Zhang , Daniel Baker , Minghu Song , Jinbo Bi

Effectively addressing the challenge of industrial Anomaly Detection (AD) necessitates an ample supply of defective samples, a constraint often hindered by their scarcity in industrial contexts. This paper introduces a novel algorithm…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Hanxi Li , Zhengxun Zhang , Hao Chen , Lin Wu , Bo Li , Deyin Liu , Mingwen Wang

Recent diffusion-based methods for material transfer rely on image fine-tuning or complex architectures with assistive networks, but face challenges including text dependency, extra computational costs, and feature misalignment. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Nisha Huang , Henglin Liu , Yizhou Lin , Kaer Huang , Chubin Chen , Jie Guo , Tong-Yee Lee , Xiu Li

As Diffusion Models have shown promising performance, a lot of efforts have been made to improve the controllability of Diffusion Models. However, how to train Diffusion Models to have the disentangled latent spaces and how to naturally…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Wonwoong Cho , Hareesh Ravi , Midhun Harikumar , Vinh Khuc , Krishna Kumar Singh , Jingwan Lu , David I. Inouye , Ajinkya Kale

Diffusion and flow-matching models have revolutionized automatic text-to-audio generation in recent times. These models are increasingly capable of generating high quality and faithful audio outputs capturing to speech and acoustic events.…

All cognitive agents are composite beings. Specifically, complex living agents consist of cells, which are themselves competent sub-agents navigating physiological and metabolic spaces. Behavior science, evolutionary developmental biology,…

Populations and Evolution · Quantitative Biology 2022-11-17 Leo Pio-Lopez , Johanna Bischof , Jennifer V. LaPalme , Michael Levin

Probabilistic Circuits (PCs) offer a computationally scalable framework for generative modeling, supporting exact and efficient inference of a wide range of probabilistic queries. While recent advances have significantly improved the…

Machine Learning · Computer Science 2025-10-07 Anji Liu , Zilei Shao , Guy Van den Broeck

The tremendous progress in neural image generation, coupled with the emergence of seemingly omnipotent vision-language models has finally enabled text-based interfaces for creating and editing images. Handling generic images requires a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Omri Avrahami , Ohad Fried , Dani Lischinski

Based on recent advanced diffusion models, Text-to-image (T2I) generation models have demonstrated their capabilities to generate diverse and high-quality images. However, leveraging their potential for real-world content creation,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-08 Sandra Zhang Ding , Jiafeng Mao , Kiyoharu Aizawa

Latent variable models are powerful statistical tools that can uncover relevant variation between patients or cells, by inferring unobserved hidden states from observable high-dimensional data. A major shortcoming of current methods,…

Machine Learning · Statistics 2022-04-12 Arber Qoku , Florian Buettner

Music editing primarily entails the modification of instrument tracks or remixing in the whole, which offers a novel reinterpretation of the original piece through a series of operations. These music processing methods hold immense…

Sound · Computer Science 2023-12-13 Bing Han , Junyu Dai , Weituo Hao , Xinyan He , Dong Guo , Jitong Chen , Yuxuan Wang , Yanmin Qian , Xuchen Song

Denoising diffusion probabilistic models (DDPMs) have been proven capable of synthesizing high-quality images with remarkable diversity when trained on large amounts of data. Typical diffusion models and modern large-scale conditional…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jingyuan Zhu , Huimin Ma , Jiansheng Chen , Jian Yuan

Structure-based drug design has seen significant advancements with the integration of artificial intelligence (AI), particularly in the generation of hit and lead compounds. However, most AI-driven approaches neglect the importance of…

Machine Learning · Computer Science 2025-11-10 Xinheng He , Yijia Zhang , Haowei Lin , Xingang Peng , Xiangzhe Kong , Mingyu Li , Jianzhu Ma

High-content phenotypic screening, including high-content imaging (HCI), has gained popularity in the last few years for its ability to characterize novel therapeutics without prior knowledge of the protein target. When combined with deep…

Diffusion models have recently driven significant breakthroughs in generative modeling. While state-of-the-art models produce high-quality samples on average, individual samples can still be low quality. Detecting such samples without human…

Machine Learning · Computer Science 2025-06-13 Metod Jazbec , Eliot Wong-Toi , Guoxuan Xia , Dan Zhang , Eric Nalisnick , Stephan Mandt

We propose TRACE, a structure-aware framework leveraging diffusion models for localized character encoding to embed data. Unlike existing methods that rely on edge features or pre-defined codebooks, TRACE exploits character structures that…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Jiale Meng , Jie Zhang , Runyi Hu , Zhe-Ming Lu , Tianwei Zhang , Yiming Li