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Transformer language models are state of the art in a multitude of NLP tasks. Despite these successes, their opaqueness remains problematic. Recent methods aiming to provide interpretability and explainability to black-box models primarily…

Computation and Language · Computer Science 2022-03-14 Felix Friedrich , Patrick Schramowski , Christopher Tauchmann , Kristian Kersting

Predicting cancer treatment outcomes requires models that are both accurate and interpretable, particularly in the presence of heterogeneous clinical data. While large language models (LLMs) have shown strong performance in biomedical NLP,…

Computation and Language · Computer Science 2025-10-21 Raghu Vamshi Hemadri , Geetha Krishna Guruju , Kristi Topollai , Anna Ewa Choromanska

With the advent of larger and more complex deep learning models, such as in Natural Language Processing (NLP), model qualities like explainability and interpretability, albeit highly desirable, are becoming harder challenges to tackle and…

Computation and Language · Computer Science 2024-01-30 Amrita Bhattacharjee , Raha Moraffah , Joshua Garland , Huan Liu

The medical adoption of NLP tools requires interpretability by end users, yet traditional explainable AI (XAI) methods are misaligned with clinical reasoning and lack clinician input. We introduce CHiRPE (Clinical High-Risk Prediction with…

Explainability is a topic of growing importance in NLP. In this work, we provide a unified perspective of explainability as a communication problem between an explainer and a layperson about a classifier's decision. We use this framework to…

Computation and Language · Computer Science 2020-10-13 Marcos V. Treviso , André F. T. Martins

Prediction of survival in patients diagnosed with a brain tumour is challenging because of heterogeneous tumour behaviours and responses to treatment. Better estimations of prognosis would support treatment planning and patient support.…

Machine Learning · Computer Science 2021-06-18 Colleen E. Charlton , Michael Tin Chung Poon , Paul M. Brennan , Jacques D. Fleuriot

Text classification is crucial for applications such as sentiment analysis and toxic text filtering, but it still faces challenges due to the complexity and ambiguity of natural language. Recent advancements in deep learning, particularly…

Computation and Language · Computer Science 2024-08-29 Lingyu Gao

Neural networks for NLP are becoming increasingly complex and widespread, and there is a growing concern if these models are responsible to use. Explaining models helps to address the safety and ethical concerns and is essential for…

Computation and Language · Computer Science 2023-11-29 Andreas Madsen , Siva Reddy , Sarath Chandar

This paper addresses the challenges posed by the unstructured nature and high-dimensional semantic complexity of electronic health record texts. A deep learning method based on attention mechanisms is proposed to achieve unified modeling…

Computation and Language · Computer Science 2025-07-03 Ting Xu , Xiaoxiao Deng , Xiandong Meng , Haifeng Yang , Yan Wu

The medical codes prediction problem from clinical notes has received substantial interest in the NLP community, and several recent studies have shown the state-of-the-art (SOTA) code prediction results of full-fledged deep learning-based…

Machine Learning · Computer Science 2022-10-31 Byung-Hak Kim , Zhongfen Deng , Philip S. Yu , Varun Ganapathi

The healthcare domain is one of the most exciting application areas for machine learning, but a lack of model transparency contributes to a lag in adoption within the industry. In this work, we explore the current art of explainability and…

Computation and Language · Computer Science 2021-07-14 Mitchell Naylor , Christi French , Samantha Terker , Uday Kamath

Prediction of medical codes from clinical notes is a practical and essential need for every healthcare delivery organization within current medical systems. Automating annotation will save significant time and excessive effort that human…

Machine Learning · Computer Science 2022-11-01 Byung-Hak Kim

Temporal Graph Neural Network (TGNN) has been receiving a lot of attention recently due to its capability in modeling time-evolving graph-related tasks. Similar to Graph Neural Networks, it is also non-trivial to interpret predictions made…

Machine Learning · Computer Science 2022-12-05 Minh N. Vu , My T. Thai

This paper contributes with a pragmatic evaluation framework for explainable Machine Learning (ML) models for clinical decision support. The study revealed a more nuanced role for ML explanation models, when these are pragmatically embedded…

Artificial Intelligence · Computer Science 2022-12-22 Oskar Wysocki , Jessica Katharine Davies , Markel Vigo , Anne Caroline Armstrong , Dónal Landers , Rebecca Lee , André Freitas

Deep Learning of neural networks has progressively become more prominent in healthcare with models reaching, or even surpassing, expert accuracy levels. However, these success stories are tainted by concerning reports on the lack of model…

Machine Learning · Computer Science 2021-11-02 Matthew Watson , Bashar Awwad Shiekh Hasan , Noura Al Moubayed

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

Machine Learning · Computer Science 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Post hoc explainers such as SHAP and LIME are used widely in business research to interpret complex machine learning models. Although they were designed to explain model predictions, there has been an increasing trend in which the…

Machine Learning · Computer Science 2026-03-10 Tong Wang , Ronilo Ragodos , Lu Feng , Yu , Hu

Most deep learning algorithms lack explanations for their predictions, which limits their deployment in clinical practice. Approaches to improve explainability, especially in medical imaging, have often been shown to convey limited…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Maxime Kayser , Cornelius Emde , Oana-Maria Camburu , Guy Parsons , Bartlomiej Papiez , Thomas Lukasiewicz

Clinical decision-making requires reasoning over incomplete, imprecise, and linguistically expressed patient narratives. While large language models (LLMs) excel at extracting latent information from natural language, they lack the…

Artificial Intelligence · Computer Science 2026-05-26 Xiaoyang Fan , Yufan Cai , Zhe Hou , Jin Song Dong

The ubiquity of machine learning based predictive models in modern society naturally leads people to ask how trustworthy those models are? In predictive modeling, it is quite common to induce a trade-off between accuracy and…

Machine Learning · Computer Science 2019-04-05 John Mitros , Brian Mac Namee