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Inverse problems, where the goal is to recover an unknown signal from noisy or incomplete measurements, are central to applications in medical imaging, remote sensing, and computational biology. Diffusion models have recently emerged as…

Machine Learning · Computer Science 2026-01-15 Shayan Mohajer Hamidi , En-Hui Yang , Ben Liang

Denoising diffusion models are a class of generative models which have recently achieved state-of-the-art results across many domains. Gradual noise is added to the data using a diffusion process, which transforms the data distribution into…

Machine Learning · Statistics 2024-06-28 Francisco Vargas , Teodora Reu , Anna Kerekes , Michael M Bronstein

The denoising process of diffusion models can be interpreted as an approximate projection of noisy samples onto the data manifold. Moreover, the noise level in these samples approximates their distance to the underlying manifold. Building…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Abulikemu Abuduweili , Chenyang Yuan , Changliu Liu , Frank Permenter

Bayesian full waveform inversion (FWI) offers uncertainty-aware subsurface models; however, posterior sampling directly on observed seismic shot records is rarely practical at the field scale because each sample requires numerous…

Geophysics · Physics 2025-12-16 Mohammad H. Taufik , Tariq Alkhalifah

Purpose: The Unadjusted Langevin Algorithm (ULA) in combination with diffusion models can generate high quality MRI reconstructions with uncertainty estimation from highly undersampled k-space data. However, sampling methods such as…

Medical Physics · Physics 2026-05-26 Moritz Blumenthal , Tina Holliber , Jonathan I. Tamir , Martin Uecker

Diffusion models have demonstrated their utility as learned priors for solving various inverse problems. However, most existing approaches are limited to linear inverse problems. This paper exploits the efficient and unsupervised posterior…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Mehmet Onurcan Kaya , Figen S. Oktem

In supervised learning for image denoising, usually the paired clean images and noisy images are collected or synthesised to train a denoising model. L2 norm loss or other distance functions are used as the objective function for training.…

Computer Vision and Pattern Recognition · Computer Science 2023-02-07 Yutong Xie , Minne Yuan , Bin Dong , Quanzheng Li

We provide a framework for solving inverse problems with diffusion models learned from linearly corrupted data. Firstly, we extend the Ambient Diffusion framework to enable training directly from measurements corrupted in the Fourier…

Computer Vision and Pattern Recognition · Computer Science 2025-04-23 Asad Aali , Giannis Daras , Brett Levac , Sidharth Kumar , Alexandros G. Dimakis , Jonathan I. Tamir

Optimal extraction of cosmological information from observations of the Cosmic Microwave Background critically relies on our ability to accurately undo the distortions caused by weak gravitational lensing. In this work, we demonstrate the…

Cosmology and Nongalactic Astrophysics · Physics 2024-06-07 Thomas Flöss , William R. Coulton , Adriaan J. Duivenvoorden , Francisco Villaescusa-Navarro , Benjamin D. Wandelt

Patient scans from MRI often suffer from noise, which hampers the diagnostic capability of such images. As a method to mitigate such artifact, denoising is largely studied both within the medical imaging community and beyond the community…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Hyungjin Chung , Eun Sun Lee , Jong Chul Ye

Diffusion models learn to denoise data and the trained denoiser is then used to generate new samples from the data distribution. In this paper, we revisit the diffusion sampling process and identify a fundamental cause of sample quality…

Machine Learning · Computer Science 2024-11-05 Yunshu Wu , Yingtao Luo , Xianghao Kong , Evangelos E. Papalexakis , Greg Ver Steeg

Recent diffusion models have achieved promising performances in audio-denoising tasks. The unique property of the reverse process could recover clean signals. However, the distribution of real-world noises does not comply with a single…

Sound · Computer Science 2024-06-14 Pu Wang , Junhui Li , Jialu Li , Liangdong Guo , Youshan Zhang

In this paper, we present the Directly Denoising Diffusion Model (DDDM): a simple and generic approach for generating realistic images with few-step sampling, while multistep sampling is still preserved for better performance. DDDMs require…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Dan Zhang , Jingjing Wang , Feng Luo

Diffusion models cannot enforce hard constraints, yet applications in the physical sciences demand exact satisfaction of conservation laws, boundary conditions, and observational consistency. In this work, we identify a corrector kernel…

Machine Learning · Computer Science 2026-05-14 Omer Rochman-Sharabi , Gilles Louppe

Diffusion magnetic resonance imaging (dMRI) plays a vital role in both clinical diagnostics and neuroscience research. However, its inherently low signal-to-noise ratio (SNR), especially under high diffusion weighting, significantly…

Quantitative Methods · Quantitative Biology 2026-02-27 Jine Xie , Zhicheng Zhang , Yunwei Chen , Yanqiu Feng , Xinyuan Zhang

Denoising Diffusion Probabilistic Models (DDPMs) have achieved impressive performance on various generation tasks. By modeling the reverse process of gradually diffusing the data distribution into a Gaussian distribution, generating a…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Zhaoyang Lyu , Xudong XU , Ceyuan Yang , Dahua Lin , Bo Dai

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman

A diffusion probabilistic model (DPM), which constructs a forward diffusion process by gradually adding noise to data points and learns the reverse denoising process to generate new samples, has been shown to handle complex data…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Zhengxiong Luo , Dayou Chen , Yingya Zhang , Yan Huang , Liang Wang , Yujun Shen , Deli Zhao , Jingren Zhou , Tieniu Tan

Training-free diffusion priors enable inverse-problem solvers without retraining, but for nonlinear forward operators data consistency often relies on repeated derivatives or inner optimization/MCMC loops with conservative step sizes,…

Machine Learning · Computer Science 2026-04-15 Minwoo Kim , Seunghyeok Shin , Hongki Lim

Recovering high-dimensional statistical structure from limited measurements is a fundamental challenge in hyperspectral imaging, where capturing full-resolution data is often infeasible due to sensor, bandwidth, or acquisition constraints.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Jonathan Monsalve , Kumar Vijay Mishra