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Computational RNA secondary structure prediction is rather well established. However, such prediction algorithms always depend on a large number of experimentally measured parameters. Here, we study how sensitive structure prediction…

Quantitative Methods · Quantitative Biology 2007-05-23 D. M. Layton , R. Bundschuh

We present self-consistent, axisymmetric core-collapse supernova simulations performed with the Prometheus-Vertex code for 18 pre-supernova models in the range of 11-28 solar masses, including progenitors recently investigated by other…

Solar and Stellar Astrophysics · Physics 2016-07-06 Alexander Summa , Florian Hanke , Hans-Thomas Janka , Tobias Melson , Andreas Marek , Bernhard Müller

Data driven generative machine learning models have recently emerged as one of the most promising approaches for new materials discovery. While the generator models can generate millions of candidates, it is critical to train fast and…

Materials Science · Physics 2021-12-14 Daniel Gleaves , Edirisuriya M. Dilanga Siriwardane , Yong Zhao , Nihang Fu , Jianjun Hu

We here focus on the behavior of supernovae that technically explode in 1D (spherical symmetry). When simulated in 3D, however, the outcomes of representative progenitors of this class are quite different in almost all relevant quantities.…

High Energy Astrophysical Phenomena · Physics 2024-05-24 Tianshu Wang , Adam Burrows

Transfer learning is beneficial for survival analysis, especially when the target study has a limited number of events. However, existing transfer learning methods rely on the restrictive assumption that the target and source studies share…

Methodology · Statistics 2026-03-13 Yu Gu , Donglin Zeng , D. Y. Lin

The explosion outcome and diagnostics of core-collapse supernovae depend sensitively on the nature of the stellar progenitor, but most studies to date have focused exclusively on one-dimensional, spherically-symmetric massive star…

Solar and Stellar Astrophysics · Physics 2022-01-14 David Vartanyan , Matthew S. B. Coleman , Adam Burrows

RNA function crucially depends on its structure. Thermodynamic models currently used for secondary structure prediction rely on computing the partition function of folding ensembles, and can thus estimate minimum free-energy structures and…

Biomolecules · Quantitative Biology 2022-07-26 Nicola Calonaci , Alisha Jones , Francesca Cuturello , Michael Sattler , Giovanni Bussi

The core-collapse supernova (CCSN) mechanism is fundamentally three-dimensional with instabilities, convection, and turbulence playing crucial roles in aiding neutrino-driven explosions. Simulations of CCNSe including accurate treatments of…

High Energy Astrophysical Phenomena · Physics 2020-02-26 Sean M. Couch , MacKenzie L. Warren , Evan P. O'Connor

We propose an optimistic estimate to evaluate the best possible fitting performance of nonlinear models. It yields an optimistic sample size that quantifies the smallest possible sample size to fit/recover a target function using a…

Machine Learning · Computer Science 2023-07-19 Yaoyu Zhang , Zhongwang Zhang , Leyang Zhang , Zhiwei Bai , Tao Luo , Zhi-Qin John Xu

We propose a versatile framework for survival analysis that combines advanced concepts from statistics with deep learning. The presented framework is based on piecewise exponential models and thereby supports various survival tasks, such as…

Machine Learning · Computer Science 2021-03-02 Philipp Kopper , Sebastian Pölsterl , Christian Wachinger , Bernd Bischl , Andreas Bender , David Rügamer

We present an initial report on 160 simulations of a highly simplified model of the post-bounce core-collapse supernova environment in three spatial dimensions (3D). We set different values of a parameter characterizing the impact of…

High Energy Astrophysical Phenomena · Physics 2016-06-16 Christian Y. Cardall , Reuben D. Budiardja

The structure of an RNA molecule plays a significant role in its biological function. Predicting structure given a one dimensional sequence of RNA nucleotide bases is a difficult and important problem. Many computer programs (known as in…

Biomolecules · Quantitative Biology 2021-06-15 Mark W. Lewis , Amit Verma , Rick Hennig

Structural failure time models are causal models for estimating the effect of time-varying treatments on a survival outcome. G-estimation and artificial censoring have been proposed to estimate the model parameters in the presence of…

Methodology · Statistics 2019-02-19 Shu Yang , Karen Pieper , Frank Cools

Understanding microstructure-property relationships (MPRs) is essential for optimising the performance of multiphase composites. Image-based poro/micro-mechanical modelling provides a non-invasive approach to exploring MPRs, but the…

Applied Physics · Physics 2025-01-22 Jinlong Fu , Wei Tan

The prediction of upcoming events in industrial processes has been a long-standing research goal since it enables optimization of manufacturing parameters, planning of equipment maintenance and more importantly prediction and eventually…

Computer Vision and Pattern Recognition · Computer Science 2020-02-26 Nikolaos Dimitriou , Lampros Leontaris , Thanasis Vafeiadis , Dimosthenis Ioannidis , Tracy Wotherspoon , Gregory Tinker , Dimitrios Tzovaras

Understanding the explosion mechanism and hydrodynamic evolution of core-collapse supernovae is a long-standing quest in astronomy. The asymmetries caused by the explosion are encoded into the line profiles which appear in the nebular phase…

High Energy Astrophysical Phenomena · Physics 2024-04-03 Bart van Baal , Anders Jerkstrand , Annop Wongwathanarat , Thomas Janka

Following a simulation approach of recent publications we explore the viability of the neutrino-heating explosion mechanism in dependence on the spatial dimension. Our results disagree with previous findings. While we also observe that…

Solar and Stellar Astrophysics · Physics 2015-05-30 Florian Hanke , Andreas Marek , Bernhard Mueller , Hans-Thomas Janka

We perform spherically-symmetric general-relativistic simulations of core collapse and the postbounce preexplosion phase in 32 presupernova stellar models of solar metallicity with zero-age-main-sequence masses of 12 M_{sun} to 120 M_{sun}.…

High Energy Astrophysical Phenomena · Physics 2013-01-31 Evan O'Connor , Christian D. Ott

Predicting the local dynamics of supercooled liquids based purely on local structure is a key challenge in our quest for understanding glassy materials. Recent years have seen an explosion of methods for making such a prediction, often via…

Soft Condensed Matter · Physics 2021-08-25 Emanuele Boattini , Frank Smallenburg , Laura Filion

We have performed ab initio neutrino radiation hydrodynamics simulations in three and two spatial dimensions (3D and 2D) of core-collapse supernovae from the same 15 $M_\odot$ progenitor through 440 ms after core bounce. Both 3D and 2D…