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Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

This paper presents the development and evaluation of a Retrieval-Augmented Generation (RAG) system for querying the United Kingdom's National Institute for Health and Care Excellence (NICE) clinical guidelines using Large Language Models…

Retrieval-augmented generation (RAG) is a paradigm that augments large language models (LLMs) with external knowledge to tackle knowledge-intensive question answering. While several benchmarks evaluate Multimodal LLMs (MLLMs) under…

Computation and Language · Computer Science 2025-08-18 Yin Wu , Quanyu Long , Jing Li , Jianfei Yu , Wenya Wang

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Large language models (LLMs), including zero-shot and few-shot paradigms, have shown promising capabilities in clinical text generation. However, real-world applications face two key challenges: (1) patient data is highly unstructured,…

Computation and Language · Computer Science 2025-07-10 Garapati Keerthana , Manik Gupta

Medical question answering (QA) requires extensive access to domain-specific knowledge. A promising direction is to enhance large language models (LLMs) with external knowledge retrieved from medical corpora or parametric knowledge stored…

Computation and Language · Computer Science 2025-10-22 Lei Li , Xiao Zhou , Yingying Zhang , Xian Wu

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

While large language models (LLMs) have achieved state-of-the-art performance on a wide range of medical question answering (QA) tasks, they still face challenges with hallucinations and outdated knowledge. Retrieval-augmented generation…

Computation and Language · Computer Science 2024-02-26 Guangzhi Xiong , Qiao Jin , Zhiyong Lu , Aidong Zhang

Retrieval-Augmented Generation (RAG) enhances Large Language Model (LLM) output by providing prior knowledge as context to input. This is beneficial for knowledge-intensive and expert reliant tasks, including legal question-answering, which…

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Retrieval-Augmented Generation (RAG) has significantly enhanced large language models (LLMs) in knowledge-intensive tasks by incorporating external knowledge retrieval. However, existing RAG frameworks primarily rely on semantic similarity…

Computation and Language · Computer Science 2025-04-18 Elahe Khatibi , Ziyu Wang , Amir M. Rahmani

Retrieval-Augmented Large Language Models (LLMs), which integrate external knowledge, have shown remarkable performance in medical domains, including clinical diagnosis. However, existing RAG methods often struggle to tailor retrieval…

Computation and Language · Computer Science 2025-10-16 Jiawei He , Mingyi Jia , Zhihao Jia , Junwen Duan , Yan Song , Jianxin Wang

In this work, we propose Oph-Guid-RAG, a multimodal visual RAG system for ophthalmology clinical question answering and decision support. We treat each guideline page as an independent evidence unit and directly retrieve page images,…

Artificial Intelligence · Computer Science 2026-03-24 Shuying Chen , Sen Cui , Zhong Cao

Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Multimodal Large Language Models (MLLMs) have significantly advanced AI-assisted medical diagnosis, but they often generate factually inconsistent responses that deviate from established medical knowledge. Retrieval-Augmented Generation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Jinhong Wang , Tajamul Ashraf , Zongyan Han , Jorma Laaksonen , Rao Mohammad Anwer

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Large Language Models (LLMs) have shown remarkable capabilities across diverse tasks, yet they face inherent limitations such as constrained parametric knowledge and high retraining costs. Retrieval-Augmented Generation (RAG) augments the…

Information Retrieval · Computer Science 2025-08-26 Leqian Li , Dianxi Shi , Jialu Zhou , Xinyu Wei , Mingyue Yang , Songchang Jin , Shaowu Yang

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao
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