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Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding

Recently impressive performance has been achieved in Concept Bottleneck Models (CBM) by utilizing the image-text alignment learned by a large pre-trained vision-language model (i.e. CLIP). However, there exist two key limitations in concept…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Minghong Zhong , Guoshuai Zou , Kanghao Chen , Dexia Chen , Ruixuan Wang

Deep learning representations are often difficult to interpret, which can hinder their deployment in sensitive applications. Concept Bottleneck Models (CBMs) have emerged as a promising approach to mitigate this issue by learning…

Machine Learning · Computer Science 2026-01-30 Antonio Almudévar , José Miguel Hernández-Lobato , Alfonso Ortega

Concept bottleneck models (CBMs), which predict human-interpretable concepts (e.g., nucleus shapes in cell images) before predicting the final output (e.g., cell type), provide insights into the decision-making processes of the model.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Winnie Pang , Xueyi Ke , Satoshi Tsutsui , Bihan Wen

Deep learning algorithms have recently gained significant attention due to their impressive performance. However, their high complexity and un-interpretable mode of operation hinders their confident deployment in real-world safety-critical…

Machine Learning · Computer Science 2024-06-28 Konstantinos P. Panousis , Dino Ienco , Diego Marcos

Concept bottleneck models (CBM) aim to produce inherently interpretable models that rely on human-understandable concepts for their predictions. However, existing approaches to design interpretable generative models based on CBMs are not…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Akshay Kulkarni , Ge Yan , Chung-En Sun , Tuomas Oikarinen , Tsui-Wei Weng

Concept Bottleneck Models (CBMs) use a set of human-interpretable concepts to predict the final task label, enabling domain experts to not only validate the CBM's predictions, but also intervene on incorrect concepts at test time. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Eric Enouen , Sainyam Galhotra

While deep learning models often lack interpretability, concept bottleneck models (CBMs) provide inherent explanations via their concept representations. Moreover, they allow users to perform interventional interactions on these concepts by…

Machine Learning · Computer Science 2024-06-05 David Steinmann , Wolfgang Stammer , Felix Friedrich , Kristian Kersting

The concept bottleneck model (CBM), as a technique improving interpretability via linking predictions to human-understandable concepts, makes high-risk and life-critical medical image classification credible. Typically, existing CBM methods…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Chunjiang Wang , Kun Zhang , Yandong Liu , Zhiyang He , Xiaodong Tao , S. Kevin Zhou

Black-box deep neural networks excel in text classification, yet their application in high-stakes domains is hindered by their lack of interpretability. To address this, we propose Text Bottleneck Models (TBM), an intrinsically…

Computation and Language · Computer Science 2024-04-04 Josh Magnus Ludan , Qing Lyu , Yue Yang , Liam Dugan , Mark Yatskar , Chris Callison-Burch

Ensuring fairness in image classification prevents models from perpetuating and amplifying bias. Concept bottleneck models (CBMs) map images to high-level, human-interpretable concepts before making predictions via a sparse, one-layer…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Schrasing Tong , Antoine Salaun , Vincent Yuan , Annabel Adeyeri , Lalana Kagal

Concept-Based Models (CBMs) are a class of deep learning models that provide interpretability by explaining predictions through high-level concepts. These models first predict concepts and then use them to perform a downstream task.…

Machine Learning · Computer Science 2025-06-27 David Debot , Pietro Barbiero , Gabriele Dominici , Giuseppe Marra

Current deep learning models are not designed to simultaneously address three fundamental questions: predict class labels to solve a given classification task (the "What?"), simulate changes in the situation to evaluate how this impacts…

Machine Learning · Computer Science 2025-02-21 Gabriele Dominici , Pietro Barbiero , Francesco Giannini , Martin Gjoreski , Giuseppe Marra , Marc Langheinrich

The miscalibration of Large Reasoning Models (LRMs) undermines their reliability in high-stakes domains, necessitating methods to accurately estimate the confidence of their long-form, multi-step outputs. To address this gap, we introduce…

Computation and Language · Computer Science 2026-01-22 Reza Khanmohammadi , Erfan Miahi , Simerjot Kaur , Ivan Brugere , Charese H. Smiley , Kundan Thind , Mohammad M. Ghassemi

Reward modeling is essential for aligning Large Language Models(LLMs) with human preferences, yet conventional reward models suffer from poor interpretability and heavy reliance on costly expert annotations. While recent rubric-based…

Artificial Intelligence · Computer Science 2026-03-10 Dengcan Liu , Fengkai Yang , Xiaohan Wang , Shurui Yan , Jiajun Chai , Jiahao Li , Yikun Ban , Zhendong Mao , Wei Lin , Guojun Yin

Concept Bottleneck Models (CBM) are inherently interpretable models that factor model decisions into human-readable concepts. They allow people to easily understand why a model is failing, a critical feature for high-stakes applications.…

Computer Vision and Pattern Recognition · Computer Science 2023-04-27 Yue Yang , Artemis Panagopoulou , Shenghao Zhou , Daniel Jin , Chris Callison-Burch , Mark Yatskar

Concept Bottleneck Models (CBMs) have been proposed as a compromise between white-box and black-box models, aiming to achieve interpretability without sacrificing accuracy. The standard training procedure for CBMs is to predefine a…

Machine Learning · Computer Science 2025-12-05 Jean Feng , Avni Kothari , Luke Zier , Chandan Singh , Yan Shuo Tan

Concept Bottleneck Models (CBMs) introduce interpretability to black-box deep learning models by predicting labels through human-understandable concepts. However, unlike humans, who identify objects at different levels of abstraction using…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Haodong Xie , Yujun Cai , Rahul Singh Maharjan , Yiwei Wang , Federico Tavella , Angelo Cangelosi

Large language models (LLMs) are increasingly evaluated and sometimes trained using automated graders such as LLM-as-judges that output scalar scores or preferences. While convenient, these approaches are often opaque: a single score rarely…

Information Retrieval · Computer Science 2026-03-24 Kaustubh D. Dhole , Eugene Agichtein

Formative assessment in STEM topics aims to promote student learning by identifying students' current understanding, thus targeting how to promote further learning. Previous studies suggest that the assessment performance of current…

Machine Learning · Computer Science 2025-04-08 Yuchen Wei , Dennis Pearl , Matthew Beckman , Rebecca J. Passonneau