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Recently, Retrieval-Augmented Generation (RAG) has achieved remarkable success in addressing the challenges of Large Language Models (LLMs) without necessitating retraining. By referencing an external knowledge base, RAG refines LLM…

Artificial Intelligence · Computer Science 2024-09-11 Boci Peng , Yun Zhu , Yongchao Liu , Xiaohe Bo , Haizhou Shi , Chuntao Hong , Yan Zhang , Siliang Tang

Evidence-based medicine (EBM) holds a crucial role in clinical application. Given suitable medical articles, doctors effectively reduce the incidence of misdiagnoses. Researchers find it efficient to use large language models (LLMs)…

Computation and Language · Computer Science 2025-11-07 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bing Qin

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Biomedical semantic question answering rooted in information retrieval can play a crucial role in keeping up to date with vast, rapidly evolving and ever-growing biomedical literature. A robust system can help researchers, healthcare…

Information Retrieval · Computer Science 2025-07-09 Shashank Verma , Fengyi Jiang , Xiangning Xue

Retrieval-Augmented Generation (RAG) demonstrates great value in alleviating outdated knowledge or hallucination by supplying LLMs with updated and relevant knowledge. However, there are still several difficulties for RAG in understanding…

Computation and Language · Computer Science 2024-04-23 Keheng Wang , Feiyu Duan , Peiguang Li , Sirui Wang , Xunliang Cai

Large language models with reasoning capabilities have demonstrated impressive performance across a wide range of domains. In clinical applications, a transparent, step-by-step reasoning process provides physicians with strong evidence to…

Artificial Intelligence · Computer Science 2025-12-16 Linjie Mu , Yannian Gu , Zhongzhen Huang , Yakun Zhu , Shaoting Zhang , Xiaofan Zhang

Retrieval-Augmented Generation (RAG) has gained significant popularity in modern Large Language Models (LLMs) due to its effectiveness in introducing new knowledge and reducing hallucinations. However, the deep understanding of RAG remains…

Computation and Language · Computer Science 2024-10-07 Jingyu Liu , Jiaen Lin , Yong Liu

Retrieval-Augmented Generation (RAG) mitigates hallucination in large language models (LLMs) by incorporating external knowledge during generation. However, the effectiveness of RAG depends not only on the design of the retriever and the…

Computation and Language · Computer Science 2026-04-15 Xudong Wang , Chaoning Zhang , Qigan Sun , Zhenzhen Huang , Chang Lu , Sheng Zheng , Zeyu Ma , Caiyan Qin , Yang Yang , Hengtao Shen

Safe and trustworthy use of Large Language Models (LLM) in the processing of healthcare documents and scientific papers could substantially help clinicians, scientists and policymakers in overcoming information overload and focusing on the…

In enterprise settings, efficiently retrieving relevant information from large and complex knowledge bases is essential for operational productivity and informed decision-making. This research presents a systematic empirical framework for…

Despite recent advances, Large Language Models (LLMs) still generate vulnerable code. Retrieval-Augmented Generation (RAG) has the potential to enhance LLMs for secure code generation by incorporating external security knowledge. However,…

Cryptography and Security · Computer Science 2026-03-17 Jiahao Shi , Tianyi Zhang

The scaling of inference computation has unlocked the potential of long-context large language models (LLMs) across diverse settings. For knowledge-intensive tasks, the increased compute is often allocated to incorporate more external…

Computation and Language · Computer Science 2025-03-04 Zhenrui Yue , Honglei Zhuang , Aijun Bai , Kai Hui , Rolf Jagerman , Hansi Zeng , Zhen Qin , Dong Wang , Xuanhui Wang , Michael Bendersky

The reuse of historical clinical trial data has significant potential to accelerate medical research and drug development. However, interoperability challenges, particularly with missing medical codes, hinders effective data integration…

Machine Learning · Computer Science 2025-03-14 Nabeel Seedat , Caterina Tozzi , Andrea Hita Ardiaca , Mihaela van der Schaar , James Weatherall , Adam Taylor

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

Large Language Models (LLMs) deployed on edge devices learn through fine-tuning and updating a certain portion of their parameters. Although such learning methods can be optimized to reduce resource utilization, the overall required…

Machine Learning · Computer Science 2024-05-09 Ruiyang Qin , Zheyu Yan , Dewen Zeng , Zhenge Jia , Dancheng Liu , Jianbo Liu , Zhi Zheng , Ningyuan Cao , Kai Ni , Jinjun Xiong , Yiyu Shi

To address the limitations of Large Language Models (LLMs) in the International Classification of Diseases (ICD) coding task, where they often produce inaccurate and incomplete prediction results due to the high-dimensional and skewed…

Computation and Language · Computer Science 2024-08-15 Rumeng Li , Xun Wang , Hong Yu

Integrating structured knowledge from tabular formats poses significant challenges within natural language processing (NLP), mainly when dealing with complex, semi-structured tables like those found in the FeTaQA dataset. These tables…

Computation and Language · Computer Science 2024-10-31 Hossein Sholehrasa , Sanaz Saki Norouzi , Pascal Hitzler , Majid Jaberi-Douraki

Detecting fraud in financial transactions typically relies on tabular models that demand heavy feature engineering to handle high-dimensional data and offer limited interpretability, making it difficult for humans to understand predictions.…

Machine Learning · Computer Science 2026-04-10 Xuwei Tan , Yao Ma , Xueru Zhang

Retrieval-augmented generation (RAG) is critical for reducing hallucinations and incorporating external knowledge into Large Language Models (LLMs). However, advanced RAG systems face a trade-off between performance and efficiency.…

Information Retrieval · Computer Science 2025-08-05 Shengbo Gong , Xianfeng Tang , Carl Yang , Wei jin

Large language models (LLMs) have demonstrated remarkable in-context reasoning capabilities across a wide range of tasks, particularly with unstructured inputs such as language or images. However, LLMs struggle to handle structured data,…

Machine Learning · Computer Science 2025-02-20 Jintang Li , Ruofan Wu , Yuchang Zhu , Huizhe Zhang , Liang Chen , Zibin Zheng