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Strongly supervised learning requires detailed knowledge of truth labels at instance levels, and in many machine learning applications this is a major drawback. Multiple instance learning (MIL) is a popular weakly supervised learning method…

Machine Learning · Computer Science 2022-02-18 Saul Fuster , Trygve Eftestøl , Kjersti Engan

Multiple Instance Learning (MIL) has emerged as a promising paradigm for Whole Slide Image (WSI) diagnosis, offering effective learning with limited annotations. However, existing MIL frameworks overlook diagnostic priorities and fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Sungrae Hong , Jiwon Jeong , Jisu Shin , Donghee Han , Sol Lee , Kyungeun Kim , Mun Yong Yi

Deep learning has shown promising results in medical image analysis, however, the lack of very large annotated datasets confines its full potential. Although transfer learning with ImageNet pre-trained classification models can alleviate…

Computer Vision and Pattern Recognition · Computer Science 2018-08-16 Ken C. L. Wong , Tanveer Syeda-Mahmood , Mehdi Moradi

Semi-supervised learning has the potential to improve the data-efficiency of training data-hungry deep neural networks, which is especially important for medical image analysis tasks where labeled data is scarce. In this work, we present a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Boon Peng Yap , Beng Koon Ng

Multiple Instance Learning (MIL) is a weakly-supervised problem in which one label is assigned to the whole bag of instances. An important class of MIL models is instance-based, where we first classify instances and then aggregate those…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Łukasz Struski , Dawid Rymarczyk , Arkadiusz Lewicki , Robert Sabiniewicz , Jacek Tabor , Bartosz Zieliński

Medical image segmentation poses challenges due to domain gaps, data modality variations, and dependency on domain knowledge or experts, especially for low- and middle-income countries (LMICs). Whereas for humans, given a few exemplars…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Chen Xu , Qiming Huang , Yuqi Hou , Jiangxing Wu , Fan Zhang , Hyung Jin Chang , Jianbo Jiao

The image-based 3D object detection task expects that the predicted 3D bounding box has a ``tightness'' projection (also referred to as cuboid), which fits the object contour well on the image while still keeping the geometric attribute on…

Computer Vision and Pattern Recognition · Computer Science 2023-09-13 Jieqi Shi , Peiliang Li , Xiaozhi Chen , Shaojie Shen

Segmentation using deep learning has shown promising directions in medical imaging as it aids in the analysis and diagnosis of diseases. Nevertheless, a main drawback of deep models is that they require a large amount of pixel-level labels,…

Computer Vision and Pattern Recognition · Computer Science 2020-04-08 Sukesh Adiga , Jose Dolz , Herve Lombaert

The detection of induced pluripotent stem cell (iPSC) colonies often needs the precise extraction of the colony features. However, existing computerized systems relied on segmentation of contours by preprocessing for classifying the colony…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Novanto Yudistira , Muthu Subash Kavitha , Jeny Rajan , Takio Kurita

We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

Accurate medical image segmentation is essential for diagnosis and treatment planning of diseases. Convolutional Neural Networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they are…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Ran Gu , Guotai Wang , Tao Song , Rui Huang , Michael Aertsen , Jan Deprest , Sébastien Ourselin , Tom Vercauteren , Shaoting Zhang

Weakly Supervised Video Anomaly Detection (WSVAD) is challenging because the binary anomaly label is only given on the video level, but the output requires snippet-level predictions. So, Multiple Instance Learning (MIL) is prevailing in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Hui Lv , Zhongqi Yue , Qianru Sun , Bin Luo , Zhen Cui , Hanwang Zhang

Due to the lack of fine-grained annotation guidance, current Multiple Instance Learning (MIL) struggles to establish a robust causal relationship between Whole Slide Image (WSI) diagnosis and evidence sub-images, just like fully supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Tianhang Nan , Yong Ding , Hao Quan , Deliang Li , Lisha Li , Guanghong Zhao , Xiaoyu Cui

Although deep convolutional neural networks achieve state-of-the-art performance across nearly all image classification tasks, their decisions are difficult to interpret. One approach that offers some level of interpretability by design is…

Computer Vision and Pattern Recognition · Computer Science 2019-12-10 Gamaleldin F. Elsayed , Simon Kornblith , Quoc V. Le

Brain tumor represents one of the most fatal cancers around the world, and is very common in children and the elderly. Accurate identification of the type and grade of tumor in the early stages plays an important role in choosing a precise…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Dunyuan Xu , Xi Wang , Jinyue Cai , Pheng-Ann Heng

Fully convolutional neural networks have made promising progress in joint liver and liver tumor segmentation. Instead of following the debates over 2D versus 3D networks (for example, pursuing the balance between large-scale 2D pretraining…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Shuxin Wang , Shilei Cao , Zhizhong Chai , Dong Wei , Kai Ma , Liansheng Wang , Yefeng Zheng

In computational pathology, whole-slide image (WSI) classification presents a formidable challenge due to its gigapixel resolution and limited fine-grained annotations. Multiple-instance learning (MIL) offers a weakly supervised solution,…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Renao Yan , Qiehe Sun , Cheng Jin , Yiqing Liu , Yonghong He , Tian Guan , Hao Chen

Multiple Instance learning (MIL) models have been extensively used in pathology to predict biomarkers and risk-stratify patients from gigapixel-sized images. Machine learning problems in medical imaging often deal with rare diseases, making…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Dinkar Juyal , Siddhant Shingi , Syed Ashar Javed , Harshith Padigela , Chintan Shah , Anand Sampat , Archit Khosla , John Abel , Amaro Taylor-Weiner

While 3D instance segmentation (3DIS) has advanced significantly, most existing methods assume that all object classes are known in advance and uniformly distributed. However, this assumption is unrealistic in dynamic, real-world…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Vishal Thengane , Jean Lahoud , Hisham Cholakkal , Rao Muhammad Anwer , Lu Yin , Xiatian Zhu , Salman Khan

Medical image segmentation typically necessitates a large and precisely annotated dataset. However, obtaining pixel-wise annotation is a labor-intensive task that requires significant effort from domain experts, making it challenging to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Heng Cai , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao