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SMILES is a linear representation of chemical structures which encodes the connection table, and the stereochemistry of a molecule as a line of text with a grammar structure denoting atoms, bonds, rings and chains, and this information can…

Machine Learning · Computer Science 2018-12-03 Arindam Paul , Dipendra Jha , Reda Al-Bahrani , Wei-keng Liao , Alok Choudhary , Ankit Agrawal

In this paper we propose the use of the Word2vec algorithm in order to obtain odor perception embeddings (or smell embeddings), only using publicly available perfume descriptions. Besides showing meaningful similarity relationships among…

Computation and Language · Computer Science 2022-03-22 Janek Amann , Manex Agirrezabal

Recent achievements in language models have showcased their extraordinary capabilities in bridging visual information with semantic language understanding. This leads us to a novel question: can language models connect textual semantics…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Yunjiao Zhou , Jianfei Yang , Han Zou , Lihua Xie

We introduce sub-sentence encoder, a contrastively-learned contextual embedding model for fine-grained semantic representation of text. In contrast to the standard practice with sentence embeddings, where the meaning of an entire sequence…

Computation and Language · Computer Science 2023-11-09 Sihao Chen , Hongming Zhang , Tong Chen , Ben Zhou , Wenhao Yu , Dian Yu , Baolin Peng , Hongwei Wang , Dan Roth , Dong Yu

The olfactory system employs responses of an ensemble of odorant receptors (ORs) to sense molecules and to generate olfactory percepts. Here we hypothesized that ORs can be viewed as 3D spatial filters that extract molecular features…

Machine Learning · Computer Science 2024-12-13 Sergey Shuvaev , Khue Tran , Khristina Samoilova , Cyrille Mascart , Alexei Koulakov

Electrical Impedance Tomography (EIT) offers a promising solution for distributed tactile sensing with minimal wiring and full-surface coverage in robotic applications. However, EIT-based tactile sensors face significant challenges during…

Robotics · Computer Science 2025-09-03 Haofeng Chen , Bedrich Himmel , Bin Li , Xiaojie Wang , Matej Hoffmann

In deep learning for drug discovery, chemical data are often represented as simplified molecular-input line-entry system (SMILES) sequences which allow for straightforward implementation of natural language processing methodologies, one…

Machine Learning · Computer Science 2023-10-05 Kathryn E. Kirchoff , Travis Maxfield , Alexander Tropsha , Shawn M. Gomez

Scanning Transmission Electron Microscopy (STEM) offers high-resolution images that are used to quantify the nanoscale atomic structure and composition of materials and biological specimens. In many cases, however, the resolution is limited…

Signal Processing · Electrical Eng. & Systems 2021-12-23 Daniel Nicholls , Alex Robinson , Jack Wells , Amirafshar Moshtaghpour , Mounib Bahri , Angus Kirkland , Nigel Browning

The Semantic Layered Embedding Diffusion (SLED) mechanism redefines the representation of hierarchical semantics within transformer-based architectures, enabling enhanced contextual consistency across a wide array of linguistic tasks. By…

Computation and Language · Computer Science 2025-03-26 Irin Kabakum , Thomas Montgomery , Daniel Ravenwood , Genevieve Harrington

Visual-textual correlations in the attention maps derived from text-to-image diffusion models are proven beneficial to dense visual prediction tasks, e.g., semantic segmentation. However, a significant challenge arises due to the input…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Jiayi Lin , Jiabo Huang , Jian Hu , Shaogang Gong

In drug-discovery-related tasks such as virtual screening, machine learning is emerging as a promising way to predict molecular properties. Conventionally, molecular fingerprints (numerical representations of molecules) are calculated…

Machine Learning · Computer Science 2019-11-13 Shion Honda , Shoi Shi , Hiroki R. Ueda

Olfactory perception plays a critical role in both human and organismal interactions, yet understanding of its underlying mechanisms and influencing factors remain insufficient. Molecular structures influence odor perception through…

Machine Learning · Computer Science 2025-02-04 HongXin Xie , JianDe Sun , Yi Shao , Shuai Li , Sujuan Hou , YuLong Sun , Jian Wang

The study of structure-spectrum relationships is essential for spectral interpretation, impacting structural elucidation and material design. Predicting spectra from molecular structures is challenging due to their complex relationships.…

Computational Physics · Physics 2024-08-29 Fanjie Xu , Wentao Guo , Feng Wang , Lin Yao , Hongshuai Wang , Fujie Tang , Zhifeng Gao , Linfeng Zhang , Weinan E , Zhong-Qun Tian , Jun Cheng

Mass spectrometry is a widely used method to study molecules and processes in medicine, life sciences, chemistry, catalysis, and industrial product quality control, among many other applications. One of the main features of some mass…

Chemical Physics · Physics 2024-07-02 Daniil A. Boiko , Valentine P. Ananikov

Effectively capturing graph node sequences in the form of vector embeddings is critical to many applications. We achieve this by (i) first learning vector embeddings of single graph nodes and (ii) then composing them to compactly represent…

Machine Learning · Computer Science 2019-11-11 Swati Rallapalli , Liang Ma , Mudhakar Srivatsa , Ananthram Swami , Heesung Kwon , Graham Bent , Christopher Simpkin

Spectroscopic techniques are essential tools for determining the structure of molecules. Different spectroscopic techniques, such as Nuclear magnetic resonance (NMR), Infrared spectroscopy, and Mass Spectrometry, provide insight into the…

Chemical Physics · Physics 2024-10-30 Marvin Alberts , Oliver Schilter , Federico Zipoli , Nina Hartrampf , Teodoro Laino

Text detection, the key technology for understanding scene text, has become an attractive research topic. For detecting various scene texts, researchers propose plenty of detectors with different advantages: detection-based models enjoy…

Computer Vision and Pattern Recognition · Computer Science 2022-01-25 Chuang Yang , Mulin Chen , Yuan Yuan , Qi Wang

Electrospray tandem mass spectrometry (ESI-MS/MS) is commonly used in high throughput metabolomics. One of the key obstacles to the effective use of this technology is the difficulty in interpreting measured spectra to accurately and…

Computational Engineering, Finance, and Science · Computer Science 2014-06-10 F. Allen , R. Greiner , D. Wishart

Small-molecule identification from tandem mass spectrometry (MS/MS) remains a bottleneck in untargeted settings where spectral libraries are incomplete. While deep learning offers a solution, current approaches typically fall into two…

Machine Learning · Computer Science 2026-03-05 Yinkai Wang , Yan Zhou Chen , Xiaohui Chen , Li-Ping Liu , Soha Hassoun

Emotion recognition using electroencephalography (EEG) signals has attracted increasing attention in recent years. However, existing methods often lack generalization in cross-corpus settings, where a model trained on one dataset is…

Human-Computer Interaction · Computer Science 2025-08-01 Qile Liu , Weishan Ye , Lingli Zhang , Zhen Liang