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Makeup transfer is not only to extract the makeup style of the reference image, but also to render the makeup style to the semantic corresponding position of the target image. However, most existing methods focus on the former and ignore…

Computer Vision and Pattern Recognition · Computer Science 2021-12-08 Zhaoyang Sun , Yaxiong Chen , Shengwu Xiong

Spatiotemporal data faces many analogous challenges to natural language text including the ordering of locations (words) in a sequence, long range dependencies between locations, and locations having multiple meanings. In this work, we…

Machine Learning · Computer Science 2024-10-15 Athanasios Tsiligkaridis , Nicholas Kalinowski , Zhongheng Li , Elizabeth Hou

Spatial transcriptomics (ST) enables spatially resolved gene profiling but remains expensive and low-throughput, limiting large-cohort studies and routine clinical use. Predicting spatial gene expression from routine hematoxylin and eosin…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Changfan Wang , Xinran Wang , Donghai Liu , Fei Su , Lulu Sun , Zhicheng Zhao , Zhu Meng

The technology to generate Spatially Resolved Transcriptomics (SRT) data is rapidly being improved and applied to investigate a variety of biological tissues. The ability to interrogate how spatially localised gene expression can lend new…

Quantitative Methods · Quantitative Biology 2021-08-04 Natalie Charitakis , Mirana Ramialison , Hieu T. Nim

Semantic segmentation based on sparse annotation has advanced in recent years. It labels only part of each object in the image, leaving the remainder unlabeled. Most of the existing approaches are time-consuming and often necessitate a…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Hui Su , Yue Ye , Wei Hua , Lechao Cheng , Mingli Song

"Is it possible to predict expression levels of different genes at a given spatial location in the routine histology image of a tumor section by modeling its stain absorption characteristics?" In this work, we propose a "stain-aware"…

Image and Video Processing · Electrical Eng. & Systems 2021-08-27 Muhammad Dawood , Kim Branson , Nasir M. Rajpoot , Fayyaz ul Amir Afsar Minhas

In medical image segmentation, supervised deep networks' success comes at the cost of requiring abundant labeled data. While asking domain experts to annotate only one or a few of the cohort's images is feasible, annotating all available…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Devavrat Tomar , Behzad Bozorgtabar , Manana Lortkipanidze , Guillaume Vray , Mohammad Saeed Rad , Jean-Philippe Thiran

Single-Cell RNA sequencing (scRNA-seq) measurements have facilitated genome-scale transcriptomic profiling of individual cells, with the hope of deconvolving cellular dynamic changes in corresponding cell sub-populations to better…

Genomics · Quantitative Biology 2021-04-06 Seyednami Niyakan , Ehsan Hajiramezanali , Shahin Boluki , Siamak Zamani Dadaneh , Xiaoning Qian

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Single-cell RNA sequencing (scRNA-seq) and spatially-resolved imaging/sequencing technologies have revolutionized biomedical research. On one hand, scRNA-seq provides information about a large portion of the transcriptome for individual…

Computational Engineering, Finance, and Science · Computer Science 2026-03-24 Arezou Rahimi , Luis A. Vale-Silva , Maria Faelth Savitski , Jovan Tanevski , Julio Saez-Rodriguez

Single-cell RNA sequencing (scRNA-seq) enables dissecting cellular heterogeneity in tissues, resulting in numerous biological discoveries. Various computational methods have been devised to delineate cell types by clustering scRNA-seq data…

Quantitative Methods · Quantitative Biology 2023-09-18 Tram Huynh , Zixuan Cang

Recent advancements in Spatial Transcriptomics (ST) technology have facilitated detailed gene expression analysis within tissue contexts. However, the high costs and methodological limitations of ST necessitate a more robust predictive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Youngmin Chung , Ji Hun Ha , Kyeong Chan Im , Joo Sang Lee

The single-cell RNA sequencing (scRNA-seq) technology enables researchers to study complex biological systems and diseases with high resolution. The central challenge is synthesizing enough scRNA-seq samples; insufficient samples can impede…

Genomics · Quantitative Biology 2023-12-25 Yixuan Wang , Shuangyin Li , Shimin DI , Lei Chen

Efficiently training accurate deep models for weakly supervised semantic segmentation (WSSS) with image-level labels is challenging and important. Recently, end-to-end WSSS methods have become the focus of research due to their high…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Rongtao Xu , Changwei Wang , Jiaxi Sun , Shibiao Xu , Weiliang Meng , Xiaopeng Zhang

This paper studies Semi-Supervised Domain Adaptation (SSDA), a practical yet under-investigated research topic that aims to learn a model of good performance using unlabeled samples and a few labeled samples in the target domain, with the…

Computer Vision and Pattern Recognition · Computer Science 2021-08-24 Kai Li , Chang Liu , Handong Zhao , Yulun Zhang , Yun Fu

Consistency learning plays a crucial role in semi-supervised medical image segmentation as it enables the effective utilization of limited annotated data while leveraging the abundance of unannotated data. The effectiveness and efficiency…

Computer Vision and Pattern Recognition · Computer Science 2023-05-26 Zhenxi Zhang , Ran Ran , Chunna Tian , Heng Zhou , Xin Li , Fan Yang , Zhicheng Jiao

Domain adaptive retrieval aims to transfer knowledge from a labeled source domain to an unlabeled target domain, enabling effective retrieval while mitigating domain discrepancies. However, existing methods encounter several fundamental…

Machine Learning · Computer Science 2026-03-31 Tianle Hu , Weijun Lv , Na Han , Xiaozhao Fang , Jie Wen , Jiaxing Li , Guoxu Zhou

In the analysis of spatially resolved transcriptomics data, detecting spatially variable genes (SVGs) is crucial. Numerous computational methods exist, but varying SVG definitions and methodologies lead to incomparable results. We review 33…

Quantitative Methods · Quantitative Biology 2024-10-04 Guanao Yan , Shuo Harper Hua , Jingyi Jessica Li

Single-cell multi-omics (scMulti-omics) refers to the paired multimodal data, such as Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq), where the regulation of each cell was measured from different modalities, i.e.…

Machine Learning · Computer Science 2024-10-18 Dian Meng , Bohao Xing , Xinlei Huang , Yanran Liu , Yijun Zhou , Yongjun xiao , Zitong Yu , Xubin Zheng

Contrastive language--audio pretraining (CLAP) has achieved remarkable success as an audio--text embedding framework, but existing approaches are limited to monaural or single-source conditions and cannot fully capture spatial information.…