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Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing…

Artificial Intelligence · Computer Science 2026-04-14 Ruiyang Li , Fang Liu , Licheng Jiao , Xinglin Xie , Jiayao Hao , Shuo Li , Xu Liu , Jingyi Yang , Lingling Li , Puhua Chen , Wenping Ma

Despite the state-of-the-art performance for medical image segmentation, deep convolutional neural networks (CNNs) have rarely provided uncertainty estimations regarding their segmentation outputs, e.g., model (epistemic) and image-based…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Guotai Wang , Wenqi Li , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

In the semantic segmentation of street scenes with neural networks, the reliability of predictions is of highest interest. The assessment of neural networks by means of uncertainties is a common ansatz to prevent safety issues. As in…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Kira Maag , Matthias Rottmann , Hanno Gottschalk

Neural Cellular Automata (NCA) is a class of Cellular Automata where the update rule is parameterized by a neural network that can be trained using gradient descent. In this paper, we focus on NCA models used for texture synthesis, where…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Ehsan Pajouheshgar , Yitao Xu , Sabine Süsstrunk

Uncertainty estimation methods using deep learning approaches strive against separating how uncertain the state of the world manifests to us via measurement (objective end) from the way this gets scrambled with the model specification and…

Machine Learning · Statistics 2023-04-21 Edgardo Solano-Carrillo

Cellular automata and their differentiable counterparts, Neural Cellular Automata (NCA), are highly expressive and capable of surprisingly complex behaviors. This paper explores how NCAs perform when applied to tasks requiring precise…

Neural and Evolutionary Computing · Computer Science 2025-12-03 Kevin Xu , Risto Miikkulainen

This paper presents a novel framework using neural cellular automata (NCA) to regenerate and predict geographic information. The model extends the idea of using NCA to generate/regenerate a specific image by training the model with various…

Computer Vision and Pattern Recognition · Computer Science 2020-09-22 Mingxiang Chen , Qichang Chen , Lei Gao , Yilin Chen , Zhecheng Wang

Learning a medical image segmentation model is an inherently ambiguous task, as uncertainties exist in both images (noise) and manual annotations (human errors and bias) used for model training. To build a trustworthy image segmentation…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Xinyu Bai , Wenjia Bai

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li

The willingness to trust predictions formulated by automatic algorithms is key in a vast number of domains. However, a vast number of deep architectures are only able to formulate predictions without an associated uncertainty. In this…

Image and Video Processing · Electrical Eng. & Systems 2022-09-28 Matteo Ferrante , Tommaso Boccato , Nicola Toschi

Neural Cellular Automata (NCA) models are trainable variations of traditional Cellular Automata (CA). Emergent motion in the patterns created by NCA has been successfully applied to synthesize dynamic textures. However, the conditions…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Yitao Xu , Ehsan Pajouheshgar , Sabine Süsstrunk

When integrating computational tools such as automatic segmentation into clinical practice, it is of utmost importance to be able to assess the level of accuracy on new data, and in particular, to detect when an automatic method fails.…

Computer Vision and Pattern Recognition · Computer Science 2017-02-14 Vanya V. Valindria , Ioannis Lavdas , Wenjia Bai , Konstantinos Kamnitsas , Eric O. Aboagye , Andrea G. Rockall , Daniel Rueckert , Ben Glocker

Semantic segmentation has become an important task in computer vision with the growth of self-driving cars, medical image segmentation, etc. Although current models provide excellent results, they are still far from perfect and while there…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Samik Some , Vinay P. Namboodiri

Image segmentation enables to extract quantitative measures from scans that can serve as imaging biomarkers for diseases. However, segmentation quality can vary substantially across scans, and therefore yield unfaithful estimates in the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-03 J. Senapati , A. Guha Roy , S. Pölsterl , D. Gutmann , S. Gatidis , C. Schlett , A. Peters , F. Bamberg , C. Wachinger

The consideration of predictive uncertainty in medical imaging with deep learning is of utmost importance. We apply estimation of both aleatoric and epistemic uncertainty by variational Bayesian inference with Monte Carlo dropout to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Max-Heinrich Laves , Sontje Ihler , Jacob F. Fast , Lüder A. Kahrs , Tobias Ortmaier

Fully convolutional neural networks (FCNs), and in particular U-Nets, have achieved state-of-the-art results in semantic segmentation for numerous medical imaging applications. Moreover, batch normalization and Dice loss have been used…

Image and Video Processing · Electrical Eng. & Systems 2020-07-06 Alireza Mehrtash , William M. Wells , Clare M. Tempany , Purang Abolmaesumi , Tina Kapur

Active learning (AL) has found wide applications in medical image segmentation, aiming to alleviate the annotation workload and enhance performance. Conventional uncertainty-based AL methods, such as entropy and Bayesian, often rely on an…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Siteng Ma , Haochang Wu , Aonghus Lawlor , Ruihai Dong

Neural Cellular Automata (NCA) models have shown remarkable capacity for pattern formation and complex global behaviors stemming from local coordination. However, in the original implementation of NCA, cells are incapable of adjusting their…

Neural and Evolutionary Computing · Computer Science 2023-05-18 Ettore Randazzo , Alexander Mordvintsev , Craig Fouts

Neural Cellular Automata (NCAs) are bio-inspired dynamical systems in which identical cells iteratively apply a learned local update rule to self-organize into complex patterns, exhibiting regeneration, robustness, and spontaneous dynamics.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ehsan Pajouheshgar , Yitao Xu , Ali Abbasi , Alexander Mordvintsev , Wenzel Jakob , Sabine Süsstrunk

Quality control (QC) of medical images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually at significant time and operator cost. We aim to…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso