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We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Kathleen M. Lewis , Natalia S. Rost , John Guttag , Adrian V. Dalca

Blood vessel segmentation is a core task in medical image analysis for the care of vascular diseases and surgical planning, yet the challenges of providing expert vascular annotations pose a major obstacle for the progress of related deep…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Erin Rainville , Melissa Ananian , Tristan Mirolla , Hassan Rivaz , Yiming Xiao

Label-free 3D brightfield microscopy offers a fast and noninvasive way to visualize cellular morphology, yet robust volumetric segmentation still typically depends on fluorescence or heavy post-processing. We address this gap by introducing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Amil Khan , Matheus Palhares Viana , Suraj Mishra , B. S. Manjunath

Foundation deep learning (DL) models are general models, designed to learn general, robust and adaptable representations of their target modality, enabling finetuning across a range of downstream tasks. These models are pretrained on large,…

Signal Processing · Electrical Eng. & Systems 2024-11-18 Ahmed Aboulfotouh , Ashkan Eshaghbeigi , Hatem Abou-Zeid

Manual annotation of volumetric medical images, such as magnetic resonance imaging (MRI) and computed tomography (CT), is a labor-intensive and time-consuming process. Recent advancements in foundation models for video object segmentation,…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Yuwen Chen , Zafer Yildiz , Qihang Li , Yaqian Chen , Haoyu Dong , Hanxue Gu , Nicholas Konz , Maciej A. Mazurowski

Foundation models for interactive segmentation in 2D natural images and videos have sparked significant interest in building 3D foundation models for medical imaging. However, the domain gaps and clinical use cases for 3D medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Yufan He , Pengfei Guo , Yucheng Tang , Andriy Myronenko , Vishwesh Nath , Ziyue Xu , Dong Yang , Can Zhao , Benjamin Simon , Mason Belue , Stephanie Harmon , Baris Turkbey , Daguang Xu , Wenqi Li

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Shaojie Li , Zhaoshuo Diao

Self-supervised learning (SSL) has advanced medical image analysis be enabling learning form large unlabelled data. However, in brain magnetic resonance imaging (MRI), most 3D models remain specialized for either segmentation of…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Amy Makawana , Abhijeet Parida , Marius George Linguraru , Julia Ive , Syed Muhammad Anwar

Ultrasound Localization Microscopy (ULM) is a non-invasive technique that allows for the imaging of micro-vessels in vivo, at depth and with a resolution on the order of ten microns. ULM is based on the sub-resolution localization of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-17 Brice Rauby , Paul Xing , Jonathan Porée , Maxime Gasse , Jean Provost

In this paper, we introduce the Volumetric Relightable Morphable Model (VRMM), a novel volumetric and parametric facial prior for 3D face modeling. While recent volumetric prior models offer improvements over traditional methods like 3D…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Haotian Yang , Mingwu Zheng , Chongyang Ma , Yu-Kun Lai , Pengfei Wan , Haibin Huang

The current neuron reconstruction pipeline for electron microscopy (EM) data usually includes automatic image segmentation followed by extensive human expert proofreading. In this work, we aim to reduce human workload by predicting…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Qihua Chen , Xuejin Chen , Chenxuan Wang , Yixiong Liu , Zhiwei Xiong , Feng Wu

The performance of meta-learning approaches for few-shot learning generally depends on three aspects: features suitable for comparison, the classifier ( base learner ) suitable for low-data scenarios, and valuable information from the…

Machine Learning · Computer Science 2020-09-15 Haoqing Wang , Zhi-Hong Deng

We present a three-dimensional foundation model for polycrystalline materials based on a masked autoencoder trained via large-scale self-supervised learning. The model is pretrained on $100{,}000$ voxelized synthetic face-centered cubic…

Computational Engineering, Finance, and Science · Computer Science 2025-12-24 Ting-Ju Wei , Chuin-Shan Chen

Accurate segmentation of brain tissues such as gray matter and white matter from magnetic resonance imaging is essential for studying brain anatomy, diagnosing neurological disorders, and monitoring disease progression. Traditional methods,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Chang Sun , Rui Shi , Tsukasa Koike , Tetsuro Sekine , Akio Morita , Tetsuya Sakai

In the medical domain, acquiring large datasets is challenging due to both accessibility issues and stringent privacy regulations. Consequently, data availability and privacy protection are major obstacles to applying machine learning in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-02 Wenwu Tang , Khaled Seyam , Bin Yang

Medical image segmentation remains challenging due to intensity inhomogeneity, noise, blurred boundaries, and irregular structures. Traditional level set methods, while effective in certain cases, often depend on approximate bias field…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Wenqi Zhao , Jiacheng Sang , Fenghua Cheng , Yonglu Shu , Dong Li , Xiaofeng Yang

Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse downstream bioinformatics tasks. However, such models often rely…

Machine Learning · Computer Science 2026-02-10 Yifan Wu , Jiyue Jiang , Xichen Ye , Yiqi Wang , Chang Zhou , Yitao Xu , Jiayang Chen , He Hu , Weizhong Zhang , Cheng Jin , Jiao Yuan , Yu Li

We present a multi-modal foundation model for astrophysical galaxy data, designed to map between simulation- and observation-based galactic features. Our encoder-only transformer flexibly ingests scalar quantities (e.g., redshifts, galaxy…

Astrophysics of Galaxies · Physics 2025-10-10 Bin Xia , Nesar Ramachandra , Azton I. Wells , Salman Habib , John Wise

Recent advancements in machine learning (ML) and deep learning (DL), particularly through the introduction of Foundation Models (FMs), have significantly enhanced surgical scene understanding within minimally invasive surgery (MIS). This…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Ufaq Khan , Umair Nawaz , Adnan Qayyum , Shazad Ashraf , Yutong Xie , Muhammad Haris Khan , Muhammad Bilal , Junaid Qadir

Atomic force microscopy (AFM or SPM) imaging is one of the best matches with machine learning (ML) analysis among microscopy techniques. The digital format of AFM images allows for direct utilization in ML algorithms without the need for…

Biological Physics · Physics 2025-01-07 Igor Sokolov
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