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Power grid fault diagnosis is a critical process hindered by its reliance on manual, error-prone methods. Technicians must manually extract reasoning logic from dense regulations and attempt to combine it with tacit expert knowledge, which…

Artificial Intelligence · Computer Science 2025-11-18 Yafang Wang , Yangjie Tian , Xiaoyu Shen , Gaoyang Zhang , Jiaze Sun , He Zhang , Ruohua Xu , Feng Zhao

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Despite being widely used to support clinical care, general-purpose large multimodal models (LMMs) have generally shown poor or inconclusive performance in medical image interpretation, particularly in pathology, where gigapixel images are…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Thomas A. Buckley , Kian R. Weihrauch , Katherine Latham , Andrew Z. Zhou , Padmini A. Manrai , Arjun K. Manrai

Clinical pathways are specialized healthcare plans that model patient treatment procedures. They are developed to provide criteria-based progression and standardize patient treatment, thereby improving care, reducing resource use, and…

Machine Learning · Computer Science 2025-12-04 Francesco Vitale , Nicola Mazzocca

Clinical AI systems routinely train on health data structurally distorted by documentation workflows, billing incentives, and terminology fragmentation. Prior work has characterised the mechanisms of this distortion: the three-forces model…

Artificial Intelligence · Computer Science 2026-04-03 Florian Odi Stummer

Histopathology is a gold standard for cancer diagnosis under a microscopic examination. However, histological tissue processing procedures result in artifacts, which are ultimately transferred to the digitized version of glass slides, known…

Tool-augmented large language model (LLM) agents promise to unify scientific reasoning with computation, yet their deployment in high-stakes domains like drug discovery is bottlenecked by two critical barriers: unconstrained tool-use…

Artificial Intelligence · Computer Science 2026-03-05 He Cao , Siyu Liu , Fan Zhang , Zijing Liu , Hao Li , Bin Feng , Shengyuan Bai , Leqing Chen , Kai Xie , Yu Li

Recent advances in large language models (LLMs) have enabled a new class of AI agents that automate multiple stages of the data science workflow by integrating planning, tool use, and multimodal reasoning across text, code, tables, and…

Cancer survival prediction from multi-omics data remains challenging because prognostic signals are high-dimensional, heterogeneous, and distributed across interacting genes and pathways. We propose PathMoG, a pathway-centric modular graph…

Machine Learning · Computer Science 2026-04-28 Di Wang , Chupei Tang , Junxiao Kong , Jixiu Zhai , Moyu Tang , Tianchi Lu

Multi-agent LLM systems are entering production -- processing documents, managing workflows, acting on behalf of users -- yet their resilience to prompt injection is still evaluated with a single binary: did the attack succeed? This leaves…

Cryptography and Security · Computer Science 2026-04-13 Haochuan Kevin Wang , Zechen Zhang

Large language models are increasingly deployed as autonomous agents for multi-step workflows in real-world software environments. However, existing agent benchmarks are limited by trajectory-opaque grading, underspecified safety and…

Artificial Intelligence · Computer Science 2026-05-08 Bowen Ye , Rang Li , Qibin Yang , Yuanxin Liu , Linli Yao , Hanglong Lv , Zhihui Xie , Chenxin An , Lei Li , Lingpeng Kong , Qi Liu , Zhifang Sui , Tong Yang

Lung cancer clinical decision support demands precise reasoning across complex, multi-stage oncological workflows. Existing multimodal large language models (MLLMs) fail to handle guideline-constrained staging and treatment reasoning. We…

Clinical practice guidelines (CPGs) provide evidence-based recommendations for patient care; however, integrating them into Artificial Intelligence (AI) remains challenging. Previous approaches, such as rule-based systems, face significant…

Artificial Intelligence · Computer Science 2026-01-08 Ruiqi Deng , Geoffrey Martin , Tony Wang , Gongbo Zhang , Yi Liu , Chunhua Weng , Yanshan Wang , Justin F Rousseau , Yifan Peng

Survival analysis is critical for cancer prognosis and treatment planning, yet existing methods lack the transparency essential for clinical adoption. While recent pathology agents have demonstrated explainability in diagnostic tasks, they…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Guolin Huang , Wenting Chen , Jiaqi Yang , Xinheng Lyu , Xiaoling Luo , Sen Yang , Xiaohan Xing , Linlin Shen

Time-series learning is the bread and butter of data-driven *clinical decision support*, and the recent explosion in ML research has demonstrated great potential in various healthcare settings. At the same time, medical time-series problems…

Machine Learning · Computer Science 2023-10-31 Daniel Jarrett , Jinsung Yoon , Ioana Bica , Zhaozhi Qian , Ari Ercole , Mihaela van der Schaar

The spatial distributions of different types of cells could reveal a cancer cell growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key hallmarks of cancer. However,…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Shidan Wang , Tao Wang , Lin Yang , Faliu Yi , Xin Luo , Yikun Yang , Adi Gazdar , Junya Fujimoto , Ignacio I. Wistuba , Bo Yao , ShinYi Lin , Yang Xie , Yousheng Mao , Guanghua Xiao

While Large Language Models (LLMs) have demonstrated potential in healthcare, they often struggle with the complex, non-linear reasoning required for accurate clinical diagnosis. Existing methods typically rely on static, linear mappings…

Computation and Language · Computer Science 2026-05-28 Zhuohan Ge , Haoyang Li , Yubo Wang , Nicole Hu , Chen Jason Zhang , Qing Li

Large language models (LLMs) show promise for clinical reasoning and decision support, but evaluation in realistic, electronic health record-congruent settings remains limited. Existing benchmarks often rely on static datasets or…

Computation and Language · Computer Science 2026-05-29 Valentina Bui Muti , Eugénie Dulout , Ziquan Fu

Cancer screening is a reasoning task. A radiologist observes findings, compares them to prior scans, integrates clinical context, and reaches a diagnostic conclusion confirmed by pathology. We present RadThinking, a Visual Question…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Wenxuan Li , Pedro R. A. S. Bassi , Xinze Zhou , Jakob Wasserthal , Alan L. Yuille , Zongwei Zhou

Complex chart understanding tasks demand advanced visual recognition and reasoning capabilities from multimodal large language models (MLLMs). However, current research provides limited coverage of complex chart scenarios and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Duo Xu , Hao Cheng , Xin Lin , Zhen Xie , Hao Wang