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Current multimodal survival prediction methods typically rely on pathology images (WSIs) and genomic data, both of which are high-dimensional and redundant, making it difficult to extract discriminative features from them and align…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Chenyu Zhao , Yingxue Xu , Fengtao Zhou , Yihui Wang , Hao Chen

The rapid development of Large Language Models (LLMs) creates new opportunities for recommender systems, especially by exploiting the side information (e.g., descriptions and analyses of items) generated by these models. However, aligning…

Information Retrieval · Computer Science 2025-04-14 Guixian Zhang , Guan Yuan , Debo Cheng , Lin Liu , Jiuyong Li , Shichao Zhang

The advent of Large Language Models (LLMs) has provided unprecedented capabilities for analyzing unstructured text data. However, deploying these models as reliable, robust, and scalable classifiers in production environments presents…

Computation and Language · Computer Science 2025-08-25 Doohee You , Andy Parisi , Zach Vander Velden , Lara Dantas Inojosa

This study presents a comparative methodological analysis of six machine learning models for survival analysis (MLSA). Using data from nearly 45,000 colorectal cancer patients in the Hospital-Based Cancer Registries of S\~ao Paulo, we…

Large language models (LLMs) show promise for extracting clinically meaningful information from unstructured health records, yet their translation into real-world settings is constrained by the lack of scalable and trustworthy validation…

Systematic reviews are crucial for synthesizing scientific evidence but remain labor-intensive, especially when extracting detailed methodological information. Large language models (LLMs) offer potential for automating methodological…

Computation and Language · Computer Science 2025-10-14 Wenqing Zhang , Trang Nguyen , Elizabeth A. Stuart , Yiqun T. Chen

Clinical decision support systems require models that are not only highly accurate but also equitable and sensitive to the implications of missed diagnoses. In this study, we introduce a knowledge-guided in-context learning (ICL) framework…

Machine Learning · Computer Science 2025-07-28 Fatemeh Nazary , Yashar Deldjoo , Tommaso Di Noia , Eugenio di Sciascio

We introduce a new approach for topic modeling that is supervised by survival analysis. Specifically, we build on recent work on unsupervised topic modeling with so-called anchor words by providing supervision through an elastic-net…

Machine Learning · Statistics 2017-12-08 George H. Chen , Jeremy C. Weiss

The existing methods for evaluating the medical knowledge of Large Language Models (LLMs) are largely based on atemporal examination-style benchmarks, while in reality, medical knowledge is inherently dynamic and continuously evolves as new…

Machine Learning · Computer Science 2026-05-14 Zihan Guan , Qiao Jin , Guangzhi Xiong , Fangyuan Chen , Mengxuan Hu , Qingyu Chen , Yifan Peng , Zhiyong Lu , Anil Vullikanti

The rapid proliferation of large language models (LLMs) in healthcare creates an urgent need for scalable and psychometrically sound evaluation methods. Conventional static benchmarks are costly to administer repeatedly, vulnerable to data…

Computation and Language · Computer Science 2026-03-26 Tianpeng Zheng , Zhehan Jiang , Jiayi Liu , Shicong Feng

Safety alignment in large language models (LLMs) is primarily evaluated under open-ended generation, where models can mitigate risk by refusing to respond. In contrast, many real-world applications place LLMs in structured decision-making…

Computation and Language · Computer Science 2026-04-21 Yuheng Chen , Zhiyu Wu , Bowen Cheng , Tetsuro Takahashi

The advancement of large language models (LLMs) has opened new frontiers in natural language processing, particularly in specialized domains like healthcare. In this paper, we propose the Incremental Curriculum-Based Fine-Tuning (ICFT)…

Computation and Language · Computer Science 2025-02-04 Robert Long , Eric Gonzalez , Harrison Fuller

We propose a constraint learning schema for fine-tuning Large Language Models (LLMs) with attribute control. Given a training corpus and control criteria formulated as a sequence-level constraint on model outputs, our method fine-tunes the…

Computation and Language · Computer Science 2024-10-10 Tao Meng , Ninareh Mehrabi , Palash Goyal , Anil Ramakrishna , Aram Galstyan , Richard Zemel , Kai-Wei Chang , Rahul Gupta , Charith Peris

Jailbreak attacks pose a serious threat to the safety of Large Language Models (LLMs) by crafting adversarial prompts that bypass alignment mechanisms, causing the models to produce harmful, restricted, or biased content. In this paper, we…

Machine Learning · Computer Science 2025-08-22 Xiangman Li , Xiaodong Wu , Qi Li , Jianbing Ni , Rongxing Lu

Large language models (LLMs) are increasingly prevalent across diverse applications. However, their enormous size limits storage and processing capabilities to a few well-resourced stakeholders. As a result, most applications rely on…

Computation and Language · Computer Science 2025-11-05 Mohammadsajad Alipour , Mohammad Mohammadi Amiri

This paper explores how large language models can leverage multi-level contextual information to predict group coordination patterns in collaborative mixed reality environments. We demonstrate that encoding individual behavioral profiles,…

Human-Computer Interaction · Computer Science 2025-11-19 Diana Romero , Xin Gao , Daniel Khalkhali , Salma Elmalaki

The current state of evaluation in survival analysis is plagued by the persistent use of evaluation metrics in ways that are misaligned with the stated modeling objective. In addition, many such evaluations are based on censoring…

Large Language Models (LLMs) have demonstrated potential in predicting mental health outcomes from online text, yet traditional classification methods often lack interpretability and robustness. This study evaluates structured reasoning…

Computation and Language · Computer Science 2026-01-09 Avinash Patil , Amardeep Kour Gedhu

Fine-tuning pre-trained language models (PLMs) has demonstrated its effectiveness on various downstream NLP tasks recently. However, in many low-resource scenarios, the conventional fine-tuning strategies cannot sufficiently capture the…

Computation and Language · Computer Science 2021-11-15 Yusheng Su , Xu Han , Yankai Lin , Zhengyan Zhang , Zhiyuan Liu , Peng Li , Jie Zhou , Maosong Sun

Large Language Models (LLMs) have shown strong promise for mining Electronic Health Records (EHRs) by reasoning over longitudinal clinical information to capture context-rich patient trajectories. However, leveraging LLMs for structured…

Computation and Language · Computer Science 2026-04-21 Arya Hadizadeh Moghaddam , Drew Ross , Mohsen Nayebi Kerdabadi , Dongjie Wang , Zijun Yao