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Laboratory workflows in pharmaceutical and biomedical research encode substantial tacit knowledge -- expert judgment about failure conditions, decision branching logic, and contextual dependencies -- that remains inaccessible to protocol…

Evaluating the quality of reasoning traces from large language models remains understudied, labor-intensive, and unreliable: current practice relies on expert rubrics, manual annotation, and slow pairwise judgments. Automated efforts are…

Artificial Intelligence · Computer Science 2026-05-28 Xue Wen Tan , Nathaniel Tan , Galen Lee , Stanley Kok

In contested domains, instruction-tuned language models must balance user-alignment pressures against faithfulness to the in-context evidence. To evaluate this tension, we introduce a controlled epistemic-conflict framework grounded in the…

Computation and Language · Computer Science 2026-03-23 Sai Koneru , Elphin Joe , Christine Kirchhoff , Jian Wu , Sarah Rajtmajer

Misalignment between claims and their cited evidence is a common failure mode in reports generated by large language models, limiting their reliability in scientific and other high-stakes settings. We present DeepSciVerify, a two-stage…

Artificial Intelligence · Computer Science 2026-05-28 Shaghayegh Sadeghi , Khashayar Khajavi , Rise Adhikari , Alexander Tessier

Large Language Models (LLMs) are increasingly entering specialized, safety-critical engineering workflows governed by strict quantitative standards and immutable physical laws, making rigorous evaluation of their reasoning capabilities…

Computation and Language · Computer Science 2026-01-08 Ayesha Gull , Muhammad Usman Safder , Rania Elbadry , Fan Zhang , Veselin Stoyanov , Preslav Nakov , Zhuohan Xie

The proliferation of disinformation demands reliable and scalable fact-checking solutions. We present Dynamic Evidence-based FAct-checking with Multimodal Experts (DEFAME), a modular, zero-shot MLLM pipeline for open-domain, text-image…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Tobias Braun , Mark Rothermel , Marcus Rohrbach , Anna Rohrbach

Large Language Models appear competent when answering general questions but often fail when pushed into domain-specific details. No existing methodology provides an out-of-the-box solution for measuring how deeply LLMs can sustain accurate…

Computation and Language · Computer Science 2026-03-26 Alexander Sheppert

Argument search aims at identifying arguments in natural language texts. In the past, this task has been addressed by a combination of keyword search and argument identification on the sentence- or document-level. However, existing…

Computation and Language · Computer Science 2021-12-02 Michael Färber , Anna Steyer

Multimodal Large Language Models are primarily trained and evaluated on aligned image-text pairs, which leaves their ability to detect and resolve real-world inconsistencies largely unexplored. In open-domain applications visual and textual…

Document-level relation extraction is a challenging task which requires reasoning over multiple sentences in order to predict relations in a document. In this paper, we pro-pose a joint training frameworkE2GRE(Entity and Evidence Guided…

Computation and Language · Computer Science 2020-08-28 Kevin Huang , Guangtao Wang , Tengyu Ma , Jing Huang

Counterfactual generation lies at the core of various machine learning tasks, including image translation and controllable text generation. This generation process usually requires the identification of the disentangled latent…

Machine Learning · Computer Science 2024-02-26 Hanqi Yan , Lingjing Kong , Lin Gui , Yuejie Chi , Eric Xing , Yulan He , Kun Zhang

Drawing meaningful conclusions from inherently multimodal clinical data (including medical imaging) requires coordinating expertise across the clinical specialty, radiology, programming, and biostatistics. This fragmented process…

Multiagent Systems · Computer Science 2026-04-15 Lucas Stoffl , Benedikt Wiestler , Johannes C. Paetzold

Self-evolving agents improve over time by reflecting on past failures, but existing evaluation is limited in two ways: it measures only task scores, leaving reflection quality unknown, and it relies on agents' own episode runs, offering no…

Artificial Intelligence · Computer Science 2026-05-29 Jiahao Huang , Fei Cheng , Junfeng Jiang , Zefan Yu , Akiko Aizawa

The proliferation of AI-generated synthetic media poses a critical threat to the integrity of digital evidence in legal and forensic contexts. Existing deepfake detection systems typically address a single modality and provide no mechanism…

Cryptography and Security · Computer Science 2026-05-29 Naisha Minnah

Detecting evidence within the context is a key step in the process of reasoning task. Evaluating and enhancing the capabilities of LLMs in evidence detection will strengthen context-based reasoning performance. This paper proposes a…

Computation and Language · Computer Science 2024-11-12 Zhouhong Gu , Lin Zhang , Xiaoxuan Zhu , Jiangjie Chen , Wenhao Huang , Yikai Zhang , Shusen Wang , Zheyu Ye , Yan Gao , Hongwei Feng , Yanghua Xiao

Medical foundation models generate narrative explanations but cannot quantify intervention effects, detect evidence conflicts, or validate literature claims, limiting clinical auditability. We propose causal compilation, a paradigm that…

Artificial Intelligence · Computer Science 2026-02-24 Yulong Li , Jianxu Chen , Xiwei Liu , Chuanyue Suo , Rong Xia , Zhixiang Lu , Yichen Li , Xinlin Zhuang , Niranjana Arun Menon , Yutong Xie , Eran Segal , Imran Razzak

We present AutoBencher, a declarative framework for automatic benchmark construction, and use it to scalably discover novel insights and vulnerabilities of existing language models. Concretely, given a few desiderata of benchmarks (e.g.,…

Computation and Language · Computer Science 2025-03-03 Xiang Lisa Li , Farzaan Kaiyom , Evan Zheran Liu , Yifan Mai , Percy Liang , Tatsunori Hashimoto

Safety moderation is pivotal for identifying harmful content. Despite the success of textual safety moderation, its multimodal counterparts remain hindered by a dual sparsity of data and supervision. Conventional reliance on binary labels…

Machine Learning · Computer Science 2026-02-04 Tianle Gu , Kexin Huang , Lingyu Li , Ruilin Luo , Shiyang Huang , Zongqi Wang , Yujiu Yang , Yan Teng , Yingchun Wang

Evidence synthesis has advanced through improved reporting standards, bias assessment tools, and analytic methods, but current workflows remain limited by a single-layer structure in which conceptual, methodological, and procedural…

Methodology · Statistics 2025-12-11 Hung Kuan Lee

Progress in computer-aided synthesis planning (CASP) is obscured by the lack of standardized evaluation infrastructure and the reliance on metrics that prioritize topological completion over chemical validity. We introduce RetroCast, a…

Machine Learning · Computer Science 2025-12-09 Anton Morgunov , Victor S. Batista
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