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Diabetic Retinopathy (DR) is a leading cause of vision loss globally. Yet despite its prevalence, the majority of affected people lack access to the specialized ophthalmologists and equipment required for assessing their condition. This can…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Alexandros Papadopoulos , Fotis Topouzis , Anastasios Delopoulos

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Background: The lack of explanations for the decisions made by algorithms such as deep learning has hampered their acceptance by the clinical community despite highly accurate results on multiple problems. Recently, attribution methods have…

Image and Video Processing · Electrical Eng. & Systems 2021-03-26 Amitojdeep Singh , J. Jothi Balaji , Mohammed Abdul Rasheed , Varadharajan Jayakumar , Rajiv Raman , Vasudevan Lakshminarayanan

Though deep learning has shown successful performance in classifying the label and severity stage of certain disease, most of them give few evidence on how to make prediction. Here, we propose to exploit the interpretability of deep…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Yuhao Niu , Lin Gu , Feng Lu , Feifan Lv , Zongji Wang , Imari Sato , Zijian Zhang , Yangyan Xiao , Xunzhang Dai , Tingting Cheng

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Diabetic retinopathy (DR) is a leading cause of blindness worldwide, necessitating early detection to prevent vision loss. Current automated DR detection systems often struggle with poor-quality images, lack interpretability, and…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Idowu Paul Okuwobi , Jingyuan Liu , Jifeng Wan , Jiaojiao Jiang

Systemic diseases such as diabetes, hypertension, atherosclerosis are among the leading causes of annual human mortality rate. It is suggested that retinal and conjunctival vascular tortuosity is a potential biomarker for such systemic…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Ashwin De Silva , Malsha V. Perera , Navodini Wijethilake , Saroj Jayasinghe , Nuwan D. Nanayakkara , Anjula De Silva

Diabetic Retinopathy (DR) is a serious and common complication of diabetes, caused by prolonged high blood sugar levels that damage the small retinal blood vessels. If left untreated, DR can progress to retinal vein occlusion and stimulate…

Image and Video Processing · Electrical Eng. & Systems 2025-04-07 Mohammad Reza Yousefi , Ali Bakrani , Amin Dehghani

People with diabetes are at risk of developing an eye disease called diabetic retinopathy (DR). This disease occurs when high blood glucose levels cause damage to blood vessels in the retina. Computer-aided DR diagnosis is a promising tool…

Computer Vision and Pattern Recognition · Computer Science 2020-11-12 Yi Zhou , Boyang Wang , Lei Huang , Shanshan Cui , Ling Shao

This paper presents a multitask deep learning model to detect all the five stages of diabetic retinopathy (DR) consisting of no DR, mild DR, moderate DR, severe DR, and proliferate DR. This multitask model consists of one classification…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Sharmin Majumder , Nasser Kehtarnavaz

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Diabetic retinopathy (DR), a microvascular complication of diabetes and a leading cause of preventable blindness, is projected to affect more than 130 million individuals worldwide by 2030. Early identification is essential to reduce…

Quantitative Methods · Quantitative Biology 2025-11-12 Jophy Lin

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine learning and deep learning models have achieved notable…

Machine Learning · Computer Science 2025-01-09 Qiuhao Lu , Rui Li , Elham Sagheb , Andrew Wen , Jinlian Wang , Liwei Wang , Jungwei W. Fan , Hongfang Liu

Junctions in the retinal vasculature are key points to be able to extract its topology, but they vary in appearance, depending on vessel density, width and branching/crossing angles. The complexity of junction patterns is usually…

Image and Video Processing · Electrical Eng. & Systems 2018-09-06 Fatmatulzehra Uslu , Anil Anthony Bharath

Accurate medical image analysis can greatly assist clinical diagnosis, but its effectiveness relies on high-quality expert annotations Obtaining pixel-level labels for medical images, particularly fundus images, remains costly and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Xi Luo , Shixin Xu , Ying Xie , JianZhong Hu , Yuwei He , Yuhui Deng , Huaxiong Huang

This study aimed to develop a machine learning (ML) algorithm capable of determining cardiovascular risk in multimodal retinal images from patients with type 1 diabetes mellitus, distinguishing between moderate, high, and very high-risk…

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Retinal disease diagnosis is critical in preventing vision loss and reducing socioeconomic burdens. Globally, over 2.2 billion people are affected by some form of vision impairment, resulting in annual productivity losses estimated at $411…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Youssef Sabiri , Walid Houmaidi , Amine Abouaomar

The diabetic retinopathy is timely diagonalized through color eye fundus images by experienced ophthalmologists, in order to recognize potential retinal features and identify early-blindness cases. In this paper, it is proposed to extract…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Ibrahim Sadek , Mohamed Elawady , Abd El Rahman Shabayek

Artificial intelligence applied to retinal images offers significant potential for recognizing signs and symptoms of retinal conditions and expediting the diagnosis of eye diseases and systemic disorders. However, developing generalized…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Boa Jang , Youngbin Ahn , Eun Kyung Choe , Chang Ki Yoon , Hyuk Jin Choi , Young-Gon Kim